Collagen, Type III Proteine (COL3)

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. Zusätzlich bieten wir Ihnen Collagen, Type III Antikörper (188) und Collagen, Type III Kits (69) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
COL3 2147 P00734
Maus COL3 COL3 14061 P19221
COL3 29251  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Human Unkonjugiert Western Blot of COLLAGEN III Lane 1: Human Collagen III Load: 100 ng per lane Primary antibody: Collagen III Antibody at 1:1000 o/n at 4°C Secondary antibody: 649 Goat anti-rabbit at 1:20,000 for 30 min at RT Block: ABIN925618 for 30 min at RT Predicted/Observed size: 138 kDa, 138 kDa 500 μg Anmelden zum Anzeigen 7 bis 9 Tage
Cow Rind (Kuh) Unkonjugiert   500 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Human Unkonjugiert Lane 1: Human Collagen III. Load: 100 ng per lane. Primary antibody: Collagen III antibody at 1:1000 ON at 4 deg C. Secondary antibody: Dylight (TM) 649 Goat anti-rabbit at 1:20, 000 for 30 min at RT. Block for 30 min at RT. 500 μg Anmelden zum Anzeigen 9 bis 11 Tage
Ratte Ratte Unkonjugiert   10 mg Anmelden zum Anzeigen 6 bis 8 Tage
Cow Rind (Kuh) Unkonjugiert   10 mg Anmelden zum Anzeigen 6 bis 8 Tage
Yeast (Pichia pastoris) Human Unkonjugiert   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
Human Human Unkonjugiert   0.5 mg Anmelden zum Anzeigen 2 bis 3 Tage
Human Human Unkonjugiert   0.5 mg Anmelden zum Anzeigen 11 bis 16 Tage
Yeast (Pichia pastoris) Human Unkonjugiert   10 mg Anmelden zum Anzeigen 2 bis 3 Tage
Cow Rind (Kuh) Unkonjugiert   0.5 mg Anmelden zum Anzeigen 3 bis 4 Tage

COL3 Proteine nach Spezies und Herkunft

Origin Exprimiert in
Human ,
Rat (Rattus)

Weitere Proteine zu Collagen, Type III (COL3) Interaktionspartnern

Human Collagen, Type III (COL3) Interaktionspartner

  1. digestion of thrombin (zeige F2 Proteine) by P. aeruginosa elastase leads to the release of the C-terminal thrombin (zeige F2 Proteine)-derived peptide FYT21, which inhibits pro-inflammatory responses to several pathogen-associated molecular patterns.

  2. Prothrombin (zeige F2 Proteine) gene mutation is rare in Budd-Chiari syndrome patients in India.

  3. In HBV-related cirrhosis, the combination of miR (zeige MLXIP Proteine)-122, AFP (zeige AFP Proteine) and PIVKA-II enables the identification of patients at higher risk of hepatocellular carcinoma development.

  4. Data, including data using network analysis, suggest that angiotensinogen (AGT (zeige AGT Proteine)), mitogen-activated protein kinase-14 (MAPK14 (zeige MAPK14 Proteine)), and prothrombin (zeige F2 Proteine) (F2) in placental villous tissues are core factors in early embryonic development; these studies involved proteomics and bioinformatics analysis of altered protein expression in placental villous tissue from early recurrent miscarriage patients in comparison to control tissues.

  5. Arg596Gln mutation is a risk factor for Chinese patients with venous thromboembolism due to its moderately decreased clotting activity but strong resistance to antithrombin (zeige SERPINC1 Proteine) inhibition.

  6. The induction of TG by BXPC3 cells was mainly driven by the TF pathway while TG generation triggered by MCF7 cells was also driven by FXII (zeige F12 Proteine) activation.

  7. we were not able to confirm the association between the polymorphisms of f5, f2, and mthfr (zeige MTHFR Proteine) and pregnancy loss in Bosnian women

  8. Platelets were activated in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients, and such activation was at least partially attributed to the thrombin (zeige F2 Proteine)-protease-activated receptors (PARs (zeige EPRS Proteine)) pathway.

  9. The meta-analysis enabled us to underline the importance of DCP (zeige ACE Proteine) in the refinement of the eligibility criteria of hepatocellular cancer (HCC (zeige FAM126A Proteine))patients for liver transplant (LT). This information, based on Japanese studies performed in the setting of living-donor LT only, needs further validation in the Western world both in the setting of post-mortem and living-donor LT.

  10. HCC (zeige FAM126A Proteine) [hepatocellular carcinoma] patients who are sero-positive for DCP (zeige ACE Proteine) [Des (zeige DES Proteine)-gamma-carboxyprothrombin] and sero-negative for AFP (zeige AFP Proteine)[Alpha-fetoprotein (zeige AFP Proteine)] have significantly higher levels of serum ALT[alanine aminotransferase (zeige ALT Proteine)]; serum ALT levels may be of diagnostic importance in AFP (zeige AFP Proteine)-negative, HBV-related HCC (zeige FAM126A Proteine) [hepatitis B virus-related hepatocellular carcinoma] patients.

Mouse (Murine) Collagen, Type III (COL3) Interaktionspartner

  1. Platelet derived microparticles formed in sepsis are a potent inducer of thrombin (zeige F2 Proteine) generation via phosphatidylserine exposure, and activation of both the intrinsic and extrinsic pathway of coagulation.

  2. These findings imply that a thrombin (zeige F2 Proteine)-pericyte interaction in the brain could be a significant mechanism responsible for blood-brain barrier dysfunction under obesity-associated diabetic conditions and thus could represent a therapeutic target for central nervous system complications of diabetes.

  3. mutations were introduced into the endogenous fII gene, resulting in expression of prothrombin (zeige F2 Proteine) carrying 3 amino acid substitutions (R157A, R268A, and K281A) to limit activation events to yield only fIIa(Meizothrombin) Homozygous fII(MZ) mice are viable, express fII levels comparable with fII(Wild type) mice, and have reproductive success.

  4. Biglycan (zeige BGN Proteine) plays a protective role during the progression of atherosclerosis in ApoE (zeige APOE Proteine)-deficient mice by inhibiting thrombin (zeige F2 Proteine) generation.

  5. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha (zeige GP1BA Proteine)-binding and heparin-binding site of thrombin (zeige F2 Proteine)

  6. thrombin (zeige F2 Proteine)/PAR-1 (zeige MARK2 Proteine) interaction regulated MCP-1 (zeige CPT1B Proteine), TF, MCSF (zeige CSF1 Proteine) and IL-6 (zeige IL6 Proteine) production.

  7. Observations illustrate the role of thrombin (zeige F2 Proteine) as a pleiotropic atherogenic molecule under conditions of hypercholesterolemia and suggest the utility of its inhibition with locally acting antithrombin (zeige SERPINC1 Proteine) nanoparticle therapeutics.

  8. Thrombin (zeige F2 Proteine)-PAR1 (zeige F2R Proteine) signaling, via nitric oxide and EPCR (zeige PROCR Proteine), promotes hematopoietic stem cell (HSC (zeige FUT1 Proteine)) mobilization.

  9. Primary tumor growth by colon cancer cells was reduced by reduction of circulating prothrombin. There were lower mitotic indices and invasiveness. This growth relied upon 2 targets of thrombin-mediated proteolysis, protease: PAR-1 and fibrinogen.

  10. Thrombin (zeige F2 Proteine) promotes sustained signaling and inflammatory gene expression through the CDC25 (zeige CDC25C Proteine) and Ras-associating domains of phospholipase C epsilon (zeige PLCE1 Proteine).

Collagen, Type III (COL3) Protein Überblick

Protein Überblick

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Genbezeichner und Symbole assoziert mit Collagen, Type III Proteine (COL3)

  • coagulation factor II, thrombin (F2)
  • coagulation factor II (F2)
  • Cf-2 Protein
  • Cf2 Protein
  • FII Protein
  • prothrombin Protein
  • PT Protein
  • RPRGL2 Protein
  • THPH1 Protein
  • thrombin Protein

Bezeichner auf Proteinebene für Collagen, Type III Proteine (COL3)

prepro-coagulation factor II , prothrombin , prothrombin B-chain , serine protease , coagulation factor 2 , thrombin

2147 Homo sapiens
14061 Mus musculus
29251 Rattus norvegicus
395306 Gallus gallus
Ausgewählte Anbieter für Collagen, Type III Proteine (COL3)
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