anti-Coiled-Coil and C2 Domain Containing 2A (CC2D2A) Antikörper

CC2D2A encodes a coiled-coil and calcium binding domain protein that appears to play a critical role in cilia formation. Zusätzlich bieten wir Ihnen CC2D2A Kits (13) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CC2D2A 57545 Q9P2K1
CC2D2A 231214 Q8CFW7
Anti-Ratte CC2D2A CC2D2A 498386  
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Top anti-CC2D2A Antikörper auf antikoerper-online.de

Showing 6 out of 6 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Meerschweinchen Kaninchen Unkonjugiert WB WB Suggested Anti-CC2D2A Antibody Titration: 1.0 ug/ml Positive Control: MDA-MB-435S Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry-Paraffin: CC2D2A Antibody [NBP1-93673] - Staining of human placenta shows strong nuclear and cytoplasmic positivity in trophoblastic cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemical staining of human placenta with CC2D2A polyclonal antibody  shows strong nuclear and cytoplasmic positivity in trophoblastic cells. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$460.00
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB   100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$380.00
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Human Kaninchen Unkonjugiert ELISA, IF/ICC, IHC, WB   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$497.47
Details

Am meisten referenzierte anti-CC2D2A Antikörper

  1. Human Polyclonal CC2D2A Primary Antibody für IHC, IHC (p) - ABIN4288475 : Wang, Tay, Soni, Perumal, Goll, Macaluso, Asara, Amack, Tsou: CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base. in Nature cell biology 2013 (PubMed)

Weitere Antikörper gegen CC2D2A Interaktionspartner

Human Coiled-Coil and C2 Domain Containing 2A (CC2D2A) Interaktionspartner

  1. Mutations in CC2D2A were the most common cause of an antenatal cystic kidney disease and a suspected ciliopathy in Saudi Arabian cohort.

  2. Using a dedicated bioinformatics algorithm for TE detection, we identified an exonic retrotransposon insertion of L1 to the CC2D2A locus in a patient with Meckel-Gruber syndrome, the most severe form of the ciliopathy phenotypes.

  3. these data support a model where CC2D2A associates with NINL (zeige NINL Antikörper) to provide a docking point for cilia-directed cargo vesicles, suggesting a mechanism by which transition zone proteins can control the protein content of the ciliary compartment.

  4. CC2D2A testing should be prioritised in patients with JS and ventriculomegaly and/or seizures. Patients with CC2D2A-related JS should be monitored for hydrocephalus and seizures.

  5. Results suggest the involvement of CC2D1A and CC2D2A in mental retardation in the Han Chinese population, and some specific haplotypes may be susceptible or protective.

  6. Mutations in MKS3 (zeige TMEM67 Antikörper) are responsible for the majority of COACH syndrome, with minor contributions from CC2D2A and RPGRIP1L (zeige RPGRIP1L Antikörper).

  7. Mutations within the CC2D2A gene are associated with Meckel and Joubert syndromes.

  8. A homozygous splice-site mutation segregating in the family with autosomal-recessive mental retardation, within a coiled-coil and C2 domain-containing gene, CC2D2A was identified.

  9. CC2D2A appears to have at least two cilia-related functions: the molecule seems to be a part of the basal body complex where the cilium is assembled from and also seems to act as a sensor for the intracellular calcium.

  10. CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290 (zeige CEP290 Antikörper).

Mouse (Murine) Coiled-Coil and C2 Domain Containing 2A (CC2D2A) Interaktionspartner

  1. CC2D2A is essential for the assembly of subdistal appendages, which anchor cytoplasmic microtubules and prime the mother centriole for axoneme biogenesis

Zebrafish Coiled-Coil and C2 Domain Containing 2A (CC2D2A) Interaktionspartner

  1. Results support participation of Rab8 (zeige RAB8A Antikörper) in OCV trafficking and identify a novel role for the TZ protein Cc2d2a in fusion of incoming ciliary-directed vesicles, through organization of the vesicle fusion machinery at the periciliary membrane.

  2. Cc2d2a, localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8 (zeige RAB8A Antikörper)-dependent vesicle trafficking and fusion.

CC2D2A Antigen-Profil

Protein Überblick

This gene encodes a coiled-coil and calcium binding domain protein that appears to play a critical role in cilia formation. Mutations in this gene cause Meckel syndrome type 6, as well as Joubert syndrome type 9. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit CC2D2A

  • coiled-coil and C2 domain containing 2A (CC2D2A) Antikörper
  • coiled-coil and C2 domain containing 2A (Cc2d2a) Antikörper
  • coiled-coil and C2 domain containing 2A L homeolog (cc2d2a.L) Antikörper
  • coiled-coil and C2 domain containing 2A (cc2d2a) Antikörper
  • 5730509K17Rik Antikörper
  • b2b1035Clo Antikörper
  • fc03c12 Antikörper
  • JBTS9 Antikörper
  • MKS6 Antikörper
  • RGD1561042 Antikörper
  • wu:fc03c12 Antikörper

Bezeichner auf Proteinebene für CC2D2A

coiled-coil and C2 domain-containing protein 2A , coiled-coil and C2 domain containing 2A , sentinel , LOW QUALITY PROTEIN: coiled-coil and C2 domain-containing protein 2A

GENE ID SPEZIES
57545 Homo sapiens
231214 Mus musculus
422830 Gallus gallus
446234 Xenopus laevis
471148 Pan troglodytes
517240 Bos taurus
570250 Danio rerio
722845 Macaca mulatta
779450 Xenopus (Silurana) tropicalis
100015780 Monodelphis domestica
100388890 Callithrix jacchus
100456809 Pongo abelii
100543518 Meleagris gallopavo
100604938 Nomascus leucogenys
100734220 Cavia porcellus
101105915 Ovis aries
498386 Rattus norvegicus
100510970 Sus scrofa
479086 Canis lupus familiaris
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