anti-Coiled-Coil Domain Containing 99 (CCDC99) Antikörper

Required for the localization of dynein and dynactin to the mitotic kintochore. Zusätzlich bieten wir Ihnen Coiled-Coil Domain Containing 99 Proteine (5) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CCDC99 54908 Q96EA4
CCDC99 70385 Q923A2
CCDC99 303037 Q3KR99
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Top anti-Coiled-Coil Domain Containing 99 Antikörper auf antikoerper-online.de

Showing 10 out of 58 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: CCDC99 Sample Type: Hela Whole cell lysates Antibody Dilution: 1.0ug/ml  SPDL1 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB CCDC99 Antibody (C-term) (ABIN657427) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the CCDC99 antibody detected the CCDC99 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen Verfügbar
$363.46
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Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis of extracts from 3T3 cells, using CCDC99 antibody.,The lane on the left is treated with the antigen-specific peptide. ABIN6275028 staining NIH-3T3 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin-embedded human rectal carcinoma labeled with Anti-Spindly/CCDC99 Polyclonal Antibody, Unconjugatedused at 1:200 dilution for 40 minutes at 37°C. 100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$317.90
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC 200 μL Anmelden zum Anzeigen 12 bis 14 Tage
$438.90
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$416.90
Details

Am meisten referenzierte anti-Coiled-Coil Domain Containing 99 Antikörper

  1. Human Polyclonal CCDC99 Primary Antibody für IP, WB - ABIN253247 : Santaguida, Tighe, DAlise, Taylor, Musacchio: Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. in The Journal of cell biology 2010 (PubMed)

Weitere Antikörper gegen Coiled-Coil Domain Containing 99 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Coiled-Coil Domain Containing 99 (CCDC99) Interaktionspartner

  1. Spindly is a novel regulator of mitotic dynein, functioning specifically to target dynein to kinetochores.

Arabidopsis thaliana Coiled-Coil Domain Containing 99 (CCDC99) Interaktionspartner

  1. posttranslational modification of TCP14/15 by SPY inhibits their proteolysis.

  2. The study revealed that SPY-dependent protein O-fucosylation plays a key role in regulating plant development.

  3. SPINDLY regulates cortex proliferation by maintaining cellular redox homeostasis

  4. SPY plays a negative role in plant abiotic stress tolerance, probably by integrating environmental stress signals via gibberellic acid and Cytokinins cross talk.

  5. Data suggest that responses of leaves and flowers to CK are mediated by SPY-dependent TCP14 and TCP15 activities.

  6. spy-4 partially suppressed the reduced abundance of CONSTANS and FLOWERING LOCUS T RNA and the late flowering of gigantea mutant plants

  7. Our results demonstrate that SPY acts as both a repressor of GA responses and a positive regulator of cytokinin signaling. Hence, SPY may play a central role in the regulation of GA/cytokinin cross talk during plant development.

  8. SPY acts in the cytosol to suppress gibberellin responses and to promote cytokinin signaling.

Human Coiled-Coil Domain Containing 99 (CCDC99) Interaktionspartner

  1. Farnesylation of Spindly is essential for its localization, & thus for proper localization of dynein & dynactin, to prometaphase kinetochores. Both Spindly and CENP-E farnesylation are required for efficient chromosome congression

  2. hSpindly is farnesylated in vivo and farnesylation is essential for its interaction with the RZZ complex and hence Kinetochore localization.

  3. Spindly is not only required for kinetochore localization of dynein but is a functional component of a mechanism that couples dynein-dependent poleward movement of chromosomes to their efficient attachment to microtubules.

  4. dynein-mediated removal of Spindly from microtubule-attached kinetochores, rather than poleward transport per se, is the critical reaction in checkpoint silencing

  5. [hSpindly] Localization of human Spindly (hSpindly) to kinetochores is controlled by the Rod/Zw10/Zwilch (RZZ) complex and Aurora B.

Mouse (Murine) Coiled-Coil Domain Containing 99 (CCDC99) Interaktionspartner

  1. Overexpression of mSpindly failed to enhance inactivation of SAC and acceleration of the meiotic process.

Coiled-Coil Domain Containing 99 (CCDC99) Antigen-Profil

Protein Überblick

Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex (By similarity).

Genbezeichner und Symbole assoziert mit CCDC99

  • CG15415 gene product from transcript CG15415-RB (Spindly) Antikörper
  • Tetratricopeptide repeat (TPR)-like superfamily protein (SPY) Antikörper
  • spindle apparatus coiled-coil protein 1 (spdl1) Antikörper
  • spindle apparatus coiled-coil protein 1 (SPDL1) Antikörper
  • spindle apparatus coiled-coil protein 1 (Spdl1) Antikörper
  • spindle apparatus coiled-coil protein 1 L homeolog (spdl1.L) Antikörper
  • 1700018I02Rik Antikörper
  • 2600001J17Rik Antikörper
  • 2810049B11Rik Antikörper
  • AA409762 Antikörper
  • Ccdc99 Antikörper
  • ccdc99-a Antikörper
  • ccdc99-b Antikörper
  • CG15415 Antikörper
  • Dmel\\CG15415 Antikörper
  • RGD1306908 Antikörper
  • spdl1 Antikörper
  • spdl1-a Antikörper
  • SPINDLY Antikörper

Bezeichner auf Proteinebene für CCDC99

spindly , CG15415-PB , Spindly-PB , coiled-coil domain containing 99 , coiled-coil domain-containing protein 99 , protein Spindly , spindle apparatus coiled-coil domain-containing protein 1 , arsenite-related gene 1 protein , hSpindly , rhabdomyosarcoma antigen MU-RMS-40.4A , rrhabdomyosarcoma antigen protein MU-RMS-40.4A , spindly homolog , Coiled-coil domain-containing protein 99-A , protein Spindly-A , spindle apparatus coiled-coil domain-containing protein 1-A

GENE ID SPEZIES
33578 Drosophila melanogaster
820327 Arabidopsis thaliana
100170491 Xenopus (Silurana) tropicalis
515158 Bos taurus
54908 Homo sapiens
70385 Mus musculus
303037 Rattus norvegicus
734358 Xenopus laevis
568360 Danio rerio
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