Coenzyme Q2 Homolog, Prenyltransferase (Yeast) Proteine (COQ2)

COQ2 encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. Zusätzlich bieten wir Ihnen COQ2 Antikörper (10) und COQ2 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
COQ2 27235 Q96H96
Ratte COQ2 COQ2 498332 Q499N4
COQ2 71883  
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Showing 3 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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COQ2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Coenzyme Q2 Homolog, Prenyltransferase (Yeast) (COQ2) Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Coenzyme Q2 Homolog, Prenyltransferase (Yeast) (COQ2) Interaktionspartner

  1. flies defective in CoQ biosynthetic gene coq2 were more susceptible to bacterial and fungal infections, while were more resistant to viruses

  2. sbo is an essential gene for Drosophila development, mutation of which leads to an extension of lifespan most likely by altering endogenous CoQ biosynthesis.

Human Coenzyme Q2 Homolog, Prenyltransferase (Yeast) (COQ2) Interaktionspartner

  1. Recessive causative mutations in COQ2 are very rare in Italian multiple system atrophy patients.

  2. We defined the structure of COQ2 with relevant implications for mutation screening in patients and demonstrated that, contrary to other COQ gene defects such as ADCK3 (zeige COQ8A Proteine), there is a correlation between COQ2 genotype and patient's phenotype.

  3. Findings provide evidence that the previously reported association of COQ2 V393A polymorphism with increased risk of multiple system atrophy in Japanese also applies to Han Chinese, as well as more broadly to other East Asian populations

  4. The V393A variant in the COQ2 gene increases risk of PD.

  5. Results indicated that COQ2 tended to play a population-specific and subtype-depended role in conferring susceptibility to multiple system atrophy

  6. This case-control study shows no evidence for an association between ALS and the V393A variant of COQ2 in Han Chinese.

  7. This study demonstrated that COQ2 gene variants associate with cerebellar subtype of multiple system atrophy in Chinese.

  8. Multiple system atrophy due to recessive COQ2 mutations (including exon dosage) was not observed in our study

  9. The recessive COQ2 mutations recently were nominated to be the genetic cause in a subset of familial and sporadic MSA (zeige TPO Proteine) cases.

  10. A novel homozygous mutation in COQ2 (c.905C>T,p.Ala302Val) found in dizygotic twins is linked to fatal infantile multisystem disease.

Mouse (Murine) Coenzyme Q2 Homolog, Prenyltransferase (Yeast) (COQ2) Interaktionspartner

COQ2 Protein Überblick

Protein Überblick

This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement.

Genbezeichner und Symbole assoziert mit COQ2

  • Coenzyme Q biosynthesis protein 2 (Coq2)
  • coenzyme Q2, polyprenyltransferase (COQ2)
  • coenzyme Q2, polyprenyltransferase (Coq2)
  • coenzyme Q2 4-hydroxybenzoate polyprenyltransferase (coq2)
  • coenzyme Q2 4-hydroxybenzoate polyprenyltransferase (Coq2)
  • 4-hydroxybenzoate polyprenyltransferase, mitochondrial (coq-2)
  • 2310002F18Rik Protein
  • CG9613 Protein
  • CL640 Protein
  • coq2 Protein
  • COQ10D1 Protein
  • Dmel\\CG9613 Protein
  • MSA1 Protein
  • RGD1306722 Protein
  • sbo Protein
  • zgc:162600 Protein

Bezeichner auf Proteinebene für COQ2

CG9613-PA , Coq2-PA , coenzyme Q biosynthesis protein 2 , small boy , 4-hydroxybenzoate polyprenyltransferase, mitochondrial , PHB:polyprenyltransferase , coenzyme Q2 homolog, prenyltransferase , para-hydroxybenzoate-polyprenyltransferase, mitochondrial , para-hydroxybenzoate--polyprenyltransferase, mitochondrial

GENE ID SPEZIES
40988 Drosophila melanogaster
27235 Homo sapiens
498332 Rattus norvegicus
100037331 Danio rerio
478457 Canis lupus familiaris
71883 Mus musculus
504633 Bos taurus
175969 Caenorhabditis elegans
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