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F10 encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. Zusätzlich bieten wir Ihnen Coagulation Factor X Antikörper (247) und Coagulation Factor X Proteine (32) und viele weitere Produktgruppen zu diesem Protein an.
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Mouse (Murine) Coagulation Factor X ELISA Kit für Sandwich ELISA - ABIN2010768
Wang, Braun, Zhang, Norström, Thorlacius: Thrombin generation in abdominal sepsis is Rho-kinase-dependent. in Biochemical and biophysical research communications 2015
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Mouse (Murine) Coagulation Factor X ELISA Kit für Sandwich ELISA - ABIN424065
Wang, Braun, Zhang, Norström, Thorlacius: Monocytes regulate systemic coagulation and inflammation in abdominal sepsis. in American journal of physiology. Heart and circulatory physiology 2015
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This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds\; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
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