anti-Coagulation Factor VIII (F8) Antikörper

F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. Zusätzlich bieten wir Ihnen Factor VIII Kits (57) und Factor VIII Proteine (22) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
F8 14069 Q06194
F8 2157 P00451
F8 302470  
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Top anti-Factor VIII Antikörper auf antikoerper-online.de

Showing 10 out of 342 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: F8 <br /> Sample Tissue: 721_B Whole Cell <br /> Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide <br />Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 2 µg/mL Lysate Quantity: 241 µg/laneGel Concentration: 2.12 % 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: Factor VIII antibody (S2194) [ABIN4493381] - in extracts from HuvEc cells. Immunocytochemistry/Immunofluorescence: Factor VIII Antibody [ABIN4493381] - Factor VIII antibody was tested 1:50 in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$473.81
Details
Hund Kaninchen Unkonjugiert WB Western blot analysis of Factor VIII expression in HeLa (A), HepG2 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged F8 is approximately 3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Hund Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded rat tibia tissue labeled with Anti-Factor VIII (FVIII) Polyclonal Antibody (ABIN668601) , Unconjugated at 1:300, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed : Mouse C57 cells labeled with Anti- Factor VIII (FVIII) Polyclonal Antibody (ABIN668601) , Unconjugated at 1:300, followed by conjugation to the secondary antibody was Goat Anti-Rabbit IgG, PE conjugated  at 1:200 for 40 minutes at 37 °C DAPI (5 µg/mL, blue) was used to stain the cell nuclei 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$307.45
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded human skin labeled with Anti-Factor VIII Polyclonal Antibody, Unconjugated (ABIN872493) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$307.45
Details
Human Kaninchen Unkonjugiert IF (cc), IF (p), IHC (p) Formalin-fixed and paraffin embedded:human colon carcinoma labeled with Anti-factor VIII(FVIII) (human) Polyclonal Antibody (ABIN728000), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded:human colon carcinoma labeled with Anti-factor VIII(FVIII)(human) Polyclonal Antibody , Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$307.45
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HuvEc cells, using Factor VIII Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 10 bis 11 Tage
$464.29
Details

F8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Factor VIII Antikörper

  1. Human Polyclonal Factor VIII Primary Antibody für WB - ABIN3042924 : Wu, Chen, Guo, He, Hu: Effects of transforming growth factor-?2 on myocilin expression and secretion in human primary cultured trabecular meshwork cells. in International journal of clinical and experimental pathology 2014 (PubMed)
    Show all 15 Pubmed References

  2. Dog (Canine) Polyclonal Factor VIII Primary Antibody für IF (p), IHC (p) - ABIN668601 : Yu, Zhang, Jiang, Wang, Zhang: Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction. in Molecular medicine reports 2015 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal Factor VIII Primary Antibody für ELISA, WB - ABIN969123 : Shovlin, Sulaiman, Govani, Jackson, Begbie: Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism. in Thrombosis and haemostasis 2007 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal Factor VIII Primary Antibody für ICC, IF - ABIN449338 : Zhu, Liu, Miao, Qu, Chi: Enhanced plasma factor VIII activity in mice via cysteine mutation using dual vectors. in Science China. Life sciences 2012 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal Factor VIII Primary Antibody für IF (cc), IF (p) - ABIN728000 : Zhou, Zhu, Zou, Wang: Changes in number and biological function of endothelial progenitor cells in hypertension disorder complicating pregnancy. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2008 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal Factor VIII Primary Antibody für IF (p), IHC (p) - ABIN872493 : Tang, Liu, Dong, Li, Li, Hou, Zheng, Lin, Ren: Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts. in Inflammation 2014 (PubMed)
    Show all 2 Pubmed References

  7. Dog (Canine) Polyclonal Factor VIII Primary Antibody für IHC, ELISA - ABIN1582291 : Shen, Li, Chung, Gillies: Retinal vascular changes after glial disruption in rats. in Journal of neuroscience research 2010 (PubMed)

  8. Human Monoclonal Factor VIII Primary Antibody für ELISA, WB - ABIN966113 : Venceslá, Corral-Rodríguez, Baena, Cornet, Domènech, Baiget, Fuentes-Prior, Tizzano: Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites. in Blood 2008 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Factor VIII Interaktionspartner

Zebrafish Coagulation Factor VIII (F8) Interaktionspartner

  1. gene is flanked by factor VII (zeige TH Antikörper) and factor X genes; gene encodes a protein homologous to factor VII (zeige TH Antikörper), but lacks critical residues for factor VII (zeige TH Antikörper) activity; functions as an inhibitor of blood coagulation in biochemical assays using zebrafish or human plasmas

Mouse (Murine) Coagulation Factor VIII (F8) Interaktionspartner

  1. Cytokine release was quantified from FVIII(-/-) splenocytes restimulated with FVIII in the absence or presence of different anti-FcgammaRIIB (CD32) Antibodies (anti-CD32 mAbs) over 6 days.

  2. results revealed localized vascular expression of FVIII and von Willebrand factor (zeige VWF Antikörper) and identified lymphatic endothelial cell as a major cellular source of FVIII in extrahepatic tissues.

  3. the results indicate that residues in the C1 and/or C2 domains of factor VIII are implicated in immunogenic factor VIII uptake, at least in vitro Conversely, in vivo, the binding to endogenous von Willebrand factor (zeige VWF Antikörper) masks the reducing effect of mutations in the C domains on factor VIII immunogenicity.

  4. data demonstrate that infusion of platelets containing FVIII triggers neither primary nor memory anti-FVIII immune response in FVIII(null) mice

  5. Both platelet-VWF (zeige VWF Antikörper) and plasma-VWF (zeige VWF Antikörper) are required for optimal platelet-derived FVIII gene therapy for hemophilia A in the presence of inhibitors.

  6. These data support the investigation of FVIII orthologs as treatment modalities in both the congenital and acquired FVIII inhibitor settings.

  7. Activatable bioengineered FIX molecules with FVIII-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.

  8. This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (zeige LRP1 Antikörper) cluster III.

  9. a fragment containing only approximately 20% of the VWF (zeige VWF Antikörper) sequence is sufficient to support FVIII stability in vivo

  10. Endothelial cells from multiple, but not all, tissues contribute to the plasma FVIII pool in the mouse.

Human Coagulation Factor VIII (F8) Interaktionspartner

  1. FVIII endocytosis is driven by interaction with LRP1 (zeige LRP1 Antikörper)

  2. A coagulation initiating pathway is revealed in which the TF-FVIIa-nascent FXa (zeige F10 Antikörper) complex activates FVIII apart from thrombin (zeige F2 Antikörper) feedback.

  3. An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII by thrombin (zeige F2 Antikörper) has been presented.

  4. Of special importance is the sequential formation of disulfide bonds with different functions in structural support of VWF (zeige VWF Antikörper) multimers, which are packaged, stored and further processed after secretion. Here, all these processes are being reviewed in detail including background information on the occurring biochemical reactions. [review]

  5. The FVIII C1 domain contributes significantly to the immune response against FVIII in acquired and congenital hemophilia inhibitor patients.

  6. the existing epidemiologic investigations with an overview of the range of possible biochemical and immunologic mechanisms that may contribute to the different immune outcomes observed with plasma-derived and recombinant FVIII products.

  7. discuss potential mechanisms through which these intronic SNPs regulate ST3GAL4 (zeige ST3GAL4 Antikörper) biosynthesis and the activity that affects VWF (zeige VWF Antikörper) and FVIII

  8. the half-life of VWF (zeige VWF Antikörper) ( approximately 15 hours) appears to be the limiting factor that has confounded attempts to extend the half-life of rFVIII.

  9. results revealed localized vascular expression of FVIII and von Willebrand factor (zeige VWF Antikörper) and identified lymphatic endothelial cell as a major cellular source of FVIII in extrahepatic tissues.

  10. the results indicate that residues in the C1 and/or C2 domains of factor VIII are implicated in immunogenic factor VIII uptake, at least in vitro Conversely, in vivo, the binding to endogenous von Willebrand factor (zeige VWF Antikörper) masks the reducing effect of mutations in the C domains on factor VIII immunogenicity.

Pig (Porcine) Coagulation Factor VIII (F8) Interaktionspartner

  1. It was concluded that VEGF and factor VIII are important growth factors associated with fetal development in pigs and are identified in all uterine segments.

  2. thrombin (zeige F2 Antikörper) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (zeige UGDH Antikörper) and by receptor-mediated up-regulation of factor XIII (zeige UGDH Antikörper) synthesis

  3. cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant

Cow (Bovine) Coagulation Factor VIII (F8) Interaktionspartner

  1. Factor VIIIc (zeige COX7A2 Antikörper) is responsible for tissue invasion during tumor progression.

Factor VIII (F8) Antigen-Profil

Protein Überblick

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Genbezeichner und Symbole assoziert mit F8

  • coagulation factor VIIi (f7i) Antikörper
  • coagulation factor VIII (F8) Antikörper
  • coagulation factor VIII, procoagulant component (F8) Antikörper
  • AHF Antikörper
  • Cf-8 Antikörper
  • Cf8 Antikörper
  • DXS1253E Antikörper
  • F8B Antikörper
  • F8C Antikörper
  • fb61d02 Antikörper
  • FVIII Antikörper
  • HEMA Antikörper
  • wu:fb61d02 Antikörper

Bezeichner auf Proteinebene für F8

Factor VIII , procoagulant component , antihemophilic factor , coagulation factor VIII , coagulation factor VIIIc , factor VIII F8B , coagulation factor VIII, procoagulant component (hemophilia A) , factor VIII , coagulation co-factor

GENE ID SPEZIES
282671 Danio rerio
14069 Mus musculus
2157 Homo sapiens
397339 Sus scrofa
403875 Canis lupus familiaris
100271720 Bos taurus
100303761 Oryctolagus cuniculus
302470 Rattus norvegicus
100359363 Ovis aries
422199 Gallus gallus
Ausgewählte Anbieter für anti-Factor VIII (F8) Antikörper
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