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C9orf86 encodes a member of the Ras superfamily of small GTPases. Zusätzlich bieten wir Ihnen Chromosome 9 Open Reading Frame 86 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal C9orf86 Primary Antibody für IF, ELISA - ABIN565902
Li, Fu, Wang, Wang, Zeng, Shao: Down-regulation of c9orf86 in human breast cancer cells inhibits cell proliferation, invasion and tumor growth and correlates with survival of breast cancer patients. in PLoS ONE 2013
RBEL1A appears to function as a novel p53 negative regulator that facilitates MDM2-dependent p53 ubiquitylation and degradation.
Rb knockdown reversed RBEL1 depletion-induced tumor suppressive effects. In conclusion, the present results suggest that RBEL1 modulates cell proliferation and G1S transition by inhibiting Rb in osteosarcoma
work identifies RABL6A as a novel negative regulator of Rb1
Breast cancer patients with high levels of C9orf86 expression showed a significant trend towards worse survival compared to patients with low C9orf86 expression.
RBEL1A and RBEL1B are novel Rab-like proteins that localize in the nucleus and cytosol and may play an important role in breast tumorigenesis
characterization of all four RBEL1 splice variants in terms of their GTPase activities, subcellular localizations, regulations & potential functions; results indicate RBEL1 proteins are linked to cell growth & survival & possess unique characteristics
This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
hypothetical protein LOC100135091
, GTP-binding protein Parf
, putative GTP-binding protein Parf
, rab-like protein 1
, rab-like protein 6
, Rab-like GTP-binding protein 1C
, partner of ARF
, Rab-like GTP-binding protein 1A