anti-Chromosome 6 Open Reading Frame 25 (C6orf25) Antikörper

C6orf25 is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. Zusätzlich bieten wir Ihnen C6orf25 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
C6orf25 406865 Q6MG59
C6orf25 80739 O95866
C6orf25 106722  
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Top anti-C6orf25 Antikörper auf antikoerper-online.de

Showing 10 out of 27 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-C6orf25 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB 100 μg 11 bis 14 Tage
$507.83
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using C6orf25 antibody. Western blot analysis of extracts of various cell lines, using C6orf25 antibody (ABIN4903093) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s. 100 μL 11 bis 13 Tage
$366.77
Details
Human Kaninchen Unkonjugiert WB 100 μg 11 bis 14 Tage
$507.83
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Mouse Testis lysates probed with Anti-C6orf25 Polyclonal Antibody, Unconjugated (ABIN2171807) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 90min in 37˚C 100 μL 14 bis 21 Tage
$317.90
Details
Human Maus Unkonjugiert WB Western Blot analysis of C6orf25 expression in transfected 293T cell line by C6orf25 MaxPab polyclonal antibody.Lane1:C6orf25 transfected lysate(26.07 KDa).Lane2:Non-transfected lysate. 50 μL 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB C6ORF25 antibody used at 1 ug/ml to detect target protein. 50 μg 9 bis 11 Tage
$449.29
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL 3 bis 7 Tage
$416.90
Details

Weitere Antikörper gegen C6orf25 Interaktionspartner

Human Chromosome 6 Open Reading Frame 25 (C6orf25) Interaktionspartner

  1. Case report of a novel MPIG6B gene mutation in a Chinese boy with pancytopenia and splenomegaly.

  2. Autosomal recessive loss-of-function mutations in G6b-B (MPIG6B) cause congenital macrothrombocytopenia with focal myelofibrosis. G6b-B has orthologous physiological functions in human and mice regulating megakaryocyte and platelet production and function.

  3. G6B seems to act through an autosomal recessive mode of disease transmission in this family and regarded as the gene responsible for the observed hematological disorder.

  4. Heparin might modulate the interaction of G6b with its as yet unidentified protein ligand

  5. G6B represents a novel inhibitory receptor found on the surface of platelets

  6. G6b-B expression is highly restricted to peripheral CD4+ T cells and up-regulated by the IL-4-induced STAT6 pathway, suggesting that G6b-B is involved in regulation of the immune response by CD4+ T cell-mediated and IL-4 induced regulatory mechanisms.

  7. G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2.

Mouse (Murine) Chromosome 6 Open Reading Frame 25 (C6orf25) Interaktionspartner

  1. Uncoupling of G6b-B from Shp1 and Shp2 results in severe macrothrombocytopenia and aberrant platelet function.

  2. these findings establish G6b-B as a major inhibitory receptor regulating megakaryocyte activation, function, and platelet production.

C6orf25 Antigen-Profil

Protein Überblick

This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit C6orf25

  • megakaryocyte and platelet inhibitory receptor G6b (Mpig6b) Antikörper
  • megakaryocyte and platelet inhibitory receptor G6b (MPIG6B) Antikörper
  • C6orf25 Antikörper
  • G6B Antikörper
  • LOC745085 Antikörper
  • NG31 Antikörper

Bezeichner auf Proteinebene für C6orf25

protein G6b , immunoglobulin receptor , G6B protein , G6b protein , ITIM-receptor G6b-B

GENE ID SPEZIES
406865 Rattus norvegicus
80739 Homo sapiens
745085 Pan troglodytes
106722 Mus musculus
617577 Bos taurus
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