anti-Chromobox Homolog 1 (CBX1) Antikörper

CBX1 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . Zusätzlich bieten wir Ihnen Chromobox Homolog 1 Proteine (8) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CBX1 10951 P83916
CBX1 12412 P83917
CBX1 360609  
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Top anti-Chromobox Homolog 1 Antikörper auf

Showing 10 out of 93 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CBX1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  OVCAR-3 cell lysate CBX1 is supported by BioGPS gene expression data to be expressed in OVCAR3 WB Suggested Anti-CBX1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: OVCAR-3 cell lysate <br /> CBX1 is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185492 (0.3µg/ml) staining of A431 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185492 (2.5µg/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
Human Kaninchen Unkonjugiert ChIPSeq, IF, WB 50 μg Anmelden zum Anzeigen 9 bis 11 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE antibody diluted at 1:1000 IHC-P Image CBX1 / HP1 beta antibody detects CBX1 protein at nucleus on C2C12 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded C2C12 xenograft. CBX1 / HP1 beta antibody , dilution: 1:500. 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CBX1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Maus Unkonjugiert ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 2:Western blot analysis using CBX1 mAb against human CBX1 (AA: 1-185) recombinant protein. (Expected MW is 47.3 kDa) Dilution: 1/500 - 1/2000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of CBX1 Antibody (C-term) (ABIN652861) in MCF-7, A2058, Y79 cell line lysates (35 µg/lane). CBX1 (arrow) was detected using the purified polyclonal antibody. CBX1 Antibody (C-term) (ABIN652861) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Fledermaus Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with CBX1 antibody ABIN337122 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-CBX1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage

Am meisten referenzierte anti-Chromobox Homolog 1 Antikörper

  1. Human Polyclonal CBX1 Primary Antibody für ChIPSeq, IF - ABIN2452034 : Kametaka, Takagi, Hayakawa, Haraguchi, Hiraoka, Yoneda: Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins. in Genes to cells : devoted to molecular & cellular mechanisms 2002 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal CBX1 Primary Antibody für ICC, IF - ABIN2668549 : Leshner, Wang, Lewis, Zheng, Chen, Santy, Wang: PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures. in Frontiers in immunology 2012 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal CBX1 Primary Antibody für WB - ABIN2775787 : Ayoub, Jeyasekharan, Bernal, Venkitaraman: HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response. in Nature 2008 (PubMed)

  4. Human Polyclonal CBX1 Primary Antibody für IHC (p), IHC - ABIN250825 : Sharma, Hwang, Pandita, Gupta, Dhar, Parenteau, Agarwal, Worman, Wellinger, Pandita: Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. in Molecular and cellular biology 2003 (PubMed)

Weitere Antikörper gegen Chromobox Homolog 1 Interaktionspartner

Human Chromobox Homolog 1 (CBX1) Interaktionspartner

  1. the prolyl residue of the PXXVXL motif appears to play a role distinct from that of Pro in the known HP1beta CSD (zeige TGFBI Antikörper)-PXVXL complexes.

  2. Data show that heterochromatin protein 1-beta (HP1beta) is a prototypic HP1 (zeige DEFA1 Antikörper) protein exemplifying most basal chromatin binding and effects.

  3. increased HP1beta expression is associated with the poor prognosis in breast cancer

  4. In this review, we summarize the current knowledge about targeting and functional mechanisms of PRCs, emphasizing the recent breakthroughs related to CBX proteins under a number of physiological and pathological conditions.

  5. Data suggest the reduction of Heterochromatin Protein 1 isoforms HP1beta followed by a decrease in HP1alpha (zeige CBX5 Antikörper) contributes to the pathogenesis of thyroid carcinomas, and their loss is a potential marker of thyroid malignancy and metastatic potential, respectively.

  6. Phosphorylation at Ser89 and Ser175 results in localized conformational changes in HP1beta that do not compromise the ability of the protein to bind chromatin.

  7. HP1 (zeige DEFA1 Antikörper) isoforms distinctly augment AR signaling and cell growth in prostate cancer. Therefore, silencing of HP1beta and HP1gamma (zeige CBX3 Antikörper) may be a promising therapeutic strategy for treatment of prostate cancer.

  8. The structural plasticity of HP1beta supports its ability to bind and connect a wide variety of binding partners in epigenetic processes.

  9. HP1beta which is associated with PCNA (zeige PCNA Antikörper) in regions of DNA repair, is bound and does not exchange with the mobile pool, suggesting that HP1beta in association with PCNA (zeige PCNA Antikörper) may be a component of a DNA repair complex.

  10. The HP1beta interactome is enriched with Lys (zeige LYZ Antikörper) methylated proteins.Role of HP1beta in DNA damage response.

Mouse (Murine) Chromobox Homolog 1 (CBX1) Interaktionspartner

  1. We demonstrate an unexpected duality in the role of HP1b: it is essential in ESCs (zeige NR2E3 Antikörper) for maintaining pluripotency, while it is required for proper differentiation in differentiated cells.

  2. The N-terminal portion of LBR (zeige LBR Antikörper) is probably responsible for the binding to HP1b.

  3. HP1b negatively regulates MMP2 (zeige MMP2 Antikörper) expression in a transcriptional level and prevents MMP2 (zeige MMP2 Antikörper) activation through reducing the expression of MT1MMP (zeige MMP14 Antikörper).

  4. Study concludes that only the 53BP1 (zeige TP53BP1 Antikörper) status in DNA lesions, induced by UVA or gamma-rays, is affected by A-type lamin (zeige LMNA Antikörper) deficiency, which was not observed for heterochromatin-related proteins HP1beta and BMI1 (zeige BMI1 Antikörper).

  5. SUV39h1 (zeige SUV39H1 Antikörper) associated with HP1 beta in fibrillarin (zeige FBL Antikörper)-positive nucleolar regions.

  6. demonstrate that a green fluorescent protein-HP1beta fusion protein is highly mobile within both the euchromatin and heterochromatin of ex vivo resting T cells; T cell activation greatly increased this mobility

  7. HP1 (zeige CBX5 Antikörper) isotypes have specific nonredundant functions; HP1 beta plays an essential role in the shuttling of corepressor transcriptional intermediary factor (TIF)1 (zeige TRIM24 Antikörper) beta from eu- to heterochromatin during cell differentiation in vivo.

  8. The localization, dynamics, and mobility of HP1beta in the in mouse preimplantation embryos (pro)nucleus were examined.

  9. HP1alpha (zeige CBX5 Antikörper) and HP1beta proteins on the heterochromatin of transcriptionally active oocytes and their absence in transcriptionally silent oocytes suggest that they are necessary for the repression of RNA synthesis in heterochromatin domains.

  10. HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions

Chromobox Homolog 1 (CBX1) Antigen-Profil

Protein Überblick

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Genbezeichner und Symbole assoziert mit CBX1

  • chromobox 1 (CBX1) Antikörper
  • chromobox 1 (Cbx1) Antikörper
  • chromobox homolog 1a (HP1 beta homolog Drosophila) (cbx1a) Antikörper
  • chromobox 1 S homeolog (cbx1.S) Antikörper
  • chromobox homolog 1b (HP1 beta homolog Drosophila) (cbx1b) Antikörper
  • Cbx Antikörper
  • Cbx-rs2 Antikörper
  • cbx1 Antikörper
  • E430007M08Rik Antikörper
  • HP1-BETA Antikörper
  • HP1B Antikörper
  • Hp1beta Antikörper
  • HP1Hs-beta Antikörper
  • HP1Hsbeta Antikörper
  • M31 Antikörper
  • MOD1 Antikörper
  • p25beta Antikörper
  • wu:fe14b09 Antikörper
  • zgc:55739 Antikörper
  • zgc:86924 Antikörper

Bezeichner auf Proteinebene für CBX1

HP1 beta homolog , chromobox homolog 1 (HP1 beta homolog Drosophila ) , chromobox protein homolog 1 , heterochromatin protein 1 homolog beta , heterochromatin protein 1-beta , heterochromatin protein p25 beta , modifier 1 protein , HP1 beta , chromobox homolog 1 , heterochromatin protein p25 , chromobox homolog 1 (HP1 beta homolog) , chromobox-like protein 1

10951 Homo sapiens
12412 Mus musculus
360609 Rattus norvegicus
326746 Danio rerio
444708 Xenopus laevis
374237 Gallus gallus
491051 Canis lupus familiaris
616506 Bos taurus
100716439 Cavia porcellus
415180 Danio rerio
Ausgewählte Anbieter für anti-Chromobox Homolog 1 (CBX1) Antikörper
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