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CHTOP encodes a small nuclear protein that is characterized by a arginine and glycine rich region. Zusätzlich bieten wir Ihnen CHTOP Proteine (6) und und viele weitere Produktgruppen zu diesem Protein an.
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the cellular level of Chtop is autoregulated via Int2 retention of its own mRNA, which subsequently undergoes NMD.
Results suggest that 5hmC plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex to selective sites on the chromosome, where it methylates H4R3 and activates the transcription of cancer-related genes.
a spatial map is produced in living cells of the sites for the interaction of two TREX subunits, Alyref and Chtop, with Nxf1.
Chtop is a component of the dynamic TREX mRNA export complex that, along with Alyref, activates the ATPase and RNA helicase activities of Uap56.
The recently identified chromatin factor Friend of Prmt1 (FOP) is a critical modulator of gamma-globin gene expression.
Fop is tightly associated with chromatin, and that it is modified by both asymmetric and symmetric arginine methylation in vivo. Fop plays an important role in the ligand-dependent activation of estrogen receptor target genes, including TFF1 (pS2).
The reduction in SRAG protein that occurs in proliferating cells was mapped with inhibitors to the G(2)/M phase of the cell cycle. As expected, the overexpression of SRAG reduced the percentage of cells in the G(2)/M phase and increased cell death.
This gene encodes a small nuclear protein that is characterized by a arginine and glycine rich region. The encoded protein may be involved in cell cycle progression. This protein interacts with protein arginine methyltransferases and plays a role in the activation of estradiol-dependent transcription. Alternate splicing results in multiple transcript variants.
chromatin target of PRMT1 protein
, friend of PRMT1 protein
, small protein rich in arginine and glycine
, Friend of PRMT1 protein
, small arginine- and glycine-rich protein
, chromatin target of PRMT1 S homeolog
, chromatin target of PRMT1b