Chorionic Gonadotropin, beta Polypeptide 5 Proteine (CGB5)

CGB5 is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic gonadotropin (CG). Zusätzlich bieten wir Ihnen CGB5 Antikörper (14) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CGB5 93659 P01233
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Human Fc Tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage

CGB5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
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Weitere Proteine zu Chorionic Gonadotropin, beta Polypeptide 5 (CGB5) Interaktionspartnern

Human Chorionic Gonadotropin, beta Polypeptide 5 (CGB5) Interaktionspartner

  1. in mole pregnancy, levels at baseline, first, second, and third weeks post-evacuation predict persistent disease

  2. carriers of minor alleles of CGB had a reduced risk of recurrent miscarriage

  3. the accumulated data indicate that only mutations with neutral or mild functional consequences might be tolerated in the major hCG-beta genes CGB5 and CGB8.

  4. Carriage of particular variants in the promoter of the CGB5 gene seems to protect against recurrent miscarriage.

  5. compared the human (45,165 bp) and chimpanzee (39,876 bp) LHB/CGB regions and hereby present evidence for structural variation resulting in discordant number of CGB genes (6 in human, 5 in chimpanzee)

  6. Data indicate the diagnostic criteria of chorionic gonadotropin beta subunit (beta-hCG) and alpha-Fetoprotein (alphaFP) in CSF and serum, which may advance the early and formal diagnosis of intracranial germ cell tumors (ICGCTs).

  7. Genetic variation within the CGB5 gene is associated with recurrent spontaneous abortion risk in Chinese women.

  8. TGF-beta enhances hCG-beta expression in glioblastoma.

  9. This study showed a link between low maternal serum hCG levels and cryptorchidism in boys from uncomplicated pregnancy.

  10. Elevated serum human chorionic gonadotropin is associated with germ-cell tumours.

  11. The effect of human chorionic gonadotropin (hCG), an LH receptor agonist, on APP beta-cleavage in the SH-SY5Y neuroblastoma cell line.

  12. Down-regulation of MTA3 and up-regulation of CGB5 and Snail are associated with preeclampsia.

  13. Serum hCG concentrations were negatively associated with maternal prepregnancy body mass index.

  14. PGDH activity was low before the ovulatory hCG stimulus, peaked 12-24 h after hCG, and was low again 36 h after hCG administration.

  15. Our finding may represent a novel methylation allelic polymorphism or gain of imprinting in CGB5 promoter leading to expressional silencing of paternal alleles and increasing susceptibility to pregnancy loss.

  16. The ISOBM TD-7 Workshop on hCG and related molecules. Towards user-oriented standardization of pregnancy and tumor diagnosis

  17. Two closely spaced Ets-2 binding sites in the proximal promoter of the human chorionic gonadotropin beta5 (hCGbeta5) gene constitute a major enhancer for hCGbeta gene expression in JAr and JEG-3 human choriocarcinoma cells and in mouse NIH3T3 cells.

  18. Agonists and antagonists will require the presence of other portions of hCGbeta in addition to the determinant loop/seat belt.

  19. Increasing concentrations of Sp1, Sp3, and AP-2alpha enhance transcription of CGbeta in differentiating term trophoblasts, whereas a different combination of factors may control expression in early placentas.

  20. OKL38 may function as an effector for human chorionic gonadotropin protection against mammary carcinogenesis.

CGB5 Protein Überblick

Protein Überblick

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

Genbezeichner und Symbole assoziert mit CGB5

  • chorionic gonadotropin beta subunit 5 (CGB5)
  • HCG Protein

Bezeichner auf Proteinebene für CGB5

chorionic gonadotropin beta 5 subunit

93659 Homo sapiens
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