Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) ELISA Kits

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Zusätzlich bieten wir Ihnen CHRNA2 Antikörper (31) und CHRNA2 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CHRNA2 170945 P12389
CHRNA2 110902 Q91X60
CHRNA2 1135 Q15822
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Top CHRNA2 ELISA Kits auf antikoerper-online.de

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Ratte
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$875.60
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Maus
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$875.60
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Huhn
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,095.60
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Human
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$875.60
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Weitere ELISA Kits für CHRNA2 Interaktionspartner

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) Interaktionspartner

  1. Chrna2-expressing Martinotti cells selectively target L5 thick-tufted type A pyramidal cells (PCs) but not thin-tufted type B PCs.

  2. Study described Chrna2 expression in the amygdala and propose that this expression is a marker of the medial subpallium-derived amygdala

  3. The results of this study suggested that loss of the mouse nAChR (zeige CHRNA4 ELISA Kits) alpha2 subunit has very limited effects on baseline behavior but does lead to the potentiation of several nicotine-modulated behaviors.

Human Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) Interaktionspartner

  1. The rare variants in CHRNA2 were significantly associated with smoking status.

  2. a heterozygous single-nucleotide substitution in CHRNA2 gene (c.1126 C>T; p. Arg376Trp) in subjects with benign familial infantile seizures

  3. CHRNA2 mutations play a causative role in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE).

  4. Results show that D478E variation in nAChR (zeige CHRNA4 ELISA Kits) alpha2 subunit increases the peak current responses of both alpha2beta2- and alpha2beta4-nAChRs; but the D478N variation in nAChR (zeige CHRNA4 ELISA Kits) alpha2 subunit only increases the peak current responses of alpha2beta2-nAChRs

  5. Level of cigarettes per day during adolescence and young adulthood is associated with CHRNB3A6, CHRNA5A3B4, and CHRNA2

  6. Results indicate that the CHRNA2 signal peptide mutation T22I modulates the function of both alpha2beta2- and alpha2beta4-nAChR (zeige CHRNA4 ELISA Kits) and decreases sensitivities to nicotine and acetylcholine, and quite possibly increasing susceptibility to nicotine dependence

  7. findings indicate that both CHRNA2 and CHRNA6 play a significant role in the etiology of ND in AA and EA smokers

  8. mutations of CHRNB2 (zeige CHRNB2 ELISA Kits) and CHRNA2 genes may be rare in Chinese autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) population.

  9. A new CHRNA2 mutation markedly increases the receptor sensitivity to acetylcholine, indicating that the nicotinic alpha 2 subunit alteration is the underlying cause.

  10. From a panel of 59 single-nucleotide polymorphisms (SNPs) located on 11 candidate genes, we identify four SNPs (one each on CHRNA5 (zeige CHRNA5 ELISA Kits) and CHRNA2 and two on CHAT) that appear to have pharmacogenetic relevance in smokin cessation therapy.

CHRNA2 Antigen-Profil

Beschreibung des Gens

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.

Genbezeichner und Symbole assoziert mit CHRNA2

  • cholinergic receptor nicotinic alpha 2 subunit (CHRNA2) Antikörper
  • cholinergic receptor, nicotinic, alpha 2a (neuronal) (chrna2a) Antikörper
  • cholinergic receptor nicotinic alpha 2 subunit (Chrna2) Antikörper
  • cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) (Chrna2) Antikörper
  • neuronal acetylcholine receptor subunit alpha-2 (CpipJ_CPIJ002436) Antikörper
  • neuronal acetylcholine receptor subunit alpha-4-like (LOC100370261) Antikörper
  • neuronal acetylcholine receptor subunit alpha-2 (Tsp_10995) Antikörper
  • ACHR Antikörper
  • Acra-2 Antikörper
  • Acra2 Antikörper
  • BC011490 Antikörper
  • chrna2 Antikörper
  • NACHRA2 Antikörper
  • zgc:136717 Antikörper

Bezeichner auf Proteinebene für CHRNA2

cholinergic receptor, nicotinic, alpha 2 (neuronal) , alpha-2 subunit, nicotinic acetylcholine receptor , cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) , neuronal acetylcholine receptor subunit alpha-2 , cholinergic receptor, nicotinic, alpha polypeptide 2a , nicotinic acetylcholine receptor , neuronal acetylcholine receptor subunit alpha-2-like , acetylcholine receptor, nicotinic, alpha 2 (neuronal)

GENE ID SPEZIES
486101 Canis lupus familiaris
395607 Gallus gallus
712868 Macaca mulatta
678575 Danio rerio
170945 Rattus norvegicus
110902 Mus musculus
6033618 Culex quinquefasciatus
100370261 Saccoglossus kowalevskii
100403598 Callithrix jacchus
100451356 Pongo abelii
10903459 Trichinella spiralis
1135 Homo sapiens
472725 Pan troglodytes
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