anti-Chloride Channel Kb (CLCNKB) Antikörper

The protein encoded by CLCNKB is a member of the family of voltage-gated chloride channels. Zusätzlich bieten wir Ihnen CLCNKB Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CLCNKB 56365 Q9WUB6
CLCNKB 1188 P51801
CLCNKB 79430 P51802
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Top anti-CLCNKB Antikörper auf antikoerper-online.de

Showing 10 out of 57 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CLCNKB Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CLCNKB Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB <span>CLCNKB Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35µg/lane).This demonstrates the CLCNKB antibody detected the CLCNKB protein (arrow).</span> 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Maus Kaninchen Unkonjugiert WB CLCNKB Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the CLCNKB antibody detected the CLCNKB protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert WB CLCNKB antibody used at 0.5 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Kaninchen Unkonjugiert WB CLCNKB antibody used at 0.25 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details

Weitere Antikörper gegen CLCNKB Interaktionspartner

Mouse (Murine) Chloride Channel Kb (CLCNKB) Interaktionspartner

  1. Loss of ClC-K2 compromises TAL (zeige TALDO1 Antikörper) function and abolishes salt reabsorption in the distal convoluted tubule. Our data suggest that ClC-K2 is crucial for renal salt reabsorption and concentrating ability. ClC-K2-deficient mice in most aspects mimic patients with Bartter's syndrome type 3.

  2. Through the combined effects of pHi and pHo on ClC-K2, might be a key regulator of NaCl absorption.

  3. IGF-1 (zeige IGF1 Antikörper), by stimulating ClC-K2 channels, promotes net Na(+) and Cl(-) reabsorption, thus reducing driving force for potassium secretion by the cortical collecting duct.

Human Chloride Channel Kb (CLCNKB) Interaktionspartner

  1. Taking advantage of the largest number of functional results of CLCNKB mutations, we reveal the functionally important domains and severe mutational spots of the hClC-Kb channel and establish the genotype-phenotype association in classic Bartter's Syndrome.

  2. Five patients had 1 (zeige SLC35A2 Antikörper) or more mutations in CLCNKB, of whom 3 had homozygous mutations and 2 had single heterozygous mutations and only in CLCNKB had hypocalciuria.

  3. Single loci of tag Single Nucleotide Polymorphisms of CLCNKA_B are not enough to increase the Essential Hypertension susceptibility, the combination of CLCNKA (zeige CLCNKA Antikörper) SNP, salt, marine products, meat, edible oil consumption is associated with elevated risk

  4. results demonstrate that the carboxyl terminus of hClC-Kb is not part of the binding site for barttin (zeige BSND Antikörper), but functionally modifies the interplay with barttin (zeige BSND Antikörper).

  5. These results demonstrate that mutations in a cluster of hydrophobic residues within transmembrane domain 1 affect barttin (zeige BSND Antikörper)-CLC-K interaction and impair gating modification by the accessory subunit

  6. we report here for the first time that ClC-Kb disease-causing mutations located around the selectivity filter can result in both reduced surface expression and hyperactivity in heterologous expression systems

  7. Case Report: 2 mutations in the CLCNKB gene, leading to a molecular diagnosis of Bartter syndrome type III in case of sudden infant death.

  8. R8W and G47R, two naturally occurring barttin (zeige BSND Antikörper) mutations identified in patients with Bartter syndrome type IV, reduce barttin (zeige BSND Antikörper) palmitoylation and CLC-K/barttin (zeige BSND Antikörper) channel activity.

  9. HEK293 cells the potentiating effect of niflumic acid (NFA) on CLC-Ka/barttin (zeige BSND Antikörper) and CLC-Kb/barttin (zeige BSND Antikörper) channels seems to be absent while the blocking efficacy of niflumic acid and benzofuran derivatives observed in oocytes is preserved

  10. study investigated the functional consequences of seven mutations; four mutants carried no current whereas others displayed a 30-60 percent reduction in conductance as compared with wild-type ClC-Kb

Xenopus laevis Chloride Channel Kb (CLCNKB) Interaktionspartner

  1. The open probability and mean open time of ClC-2 (zeige CLCN2 Antikörper) was voltage dependent, decreasing dramatically as the patches were depolarized. ClC-2 (zeige CLCN2 Antikörper) is uniquely suitable to promote anion secretion with little anion reabsorption.

CLCNKB Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CLCNKB

  • chloride voltage-gated channel Kb (CLCNKB) Antikörper
  • chloride channel Kb (CLCNKB) Antikörper
  • chloride channel K (clcnk) Antikörper
  • chloride channel protein ClC-Ka (LOC100017912) Antikörper
  • chloride channel protein ClC-Kb (LOC100400180) Antikörper
  • chloride channel protein ClC-Kb (LOC100590605) Antikörper
  • chloride channel Ka (CLCNKA) Antikörper
  • chloride channel, voltage-sensitive Kb (Clcnkb) Antikörper
  • chloride channel, voltage-sensitive Ka (CLCNKA) Antikörper
  • chloride voltage-gated channel Ka (CLCNKA) Antikörper
  • chloride voltage-gated channel Kb (Clcnkb) Antikörper
  • chloride channel, voltage-sensitive Kb L homeolog (clcnkb.L) Antikörper
  • ClC-k Antikörper
  • ClC-K2 Antikörper
  • ClC-K2L Antikörper
  • Clc-Ka Antikörper
  • clc-kb Antikörper
  • Clck2 Antikörper
  • clckb Antikörper
  • Clcnk1l Antikörper
  • CLCNKA Antikörper
  • clcnka-A Antikörper
  • CLCNKB Antikörper
  • clk-k2 Antikörper
  • DKFZp469N0132 Antikörper
  • x6clck Antikörper
  • xCIC-K Antikörper
  • xClC-K Antikörper
  • zgc:64141 Antikörper

Bezeichner auf Proteinebene für CLCNKB

chloride channel Kb , chloride channel Ka , CIC-K , chloride channel protein ClC-Kb-like , chloride channel K1-like; putative basolateral cTAL chloride channel ClC-Ka , chloride channel protein ClC-Kb , clC-K2 , putative basolateral mTAL chloride channel ClC-Ka , Chloride channel protein ClC-Kb , chloride channel protein ClC-Ka , clC-K1 , chloride channel, kidney, B , chloride channel K2

GENE ID SPEZIES
703476 Macaca mulatta
428190 Gallus gallus
456470 Pan troglodytes
100171573 Pongo abelii
393353 Danio rerio
100017912 Monodelphis domestica
100400180 Callithrix jacchus
100590605 Nomascus leucogenys
538145 Bos taurus
56365 Mus musculus
100009213 Oryctolagus cuniculus
1188 Homo sapiens
487422 Canis lupus familiaris
79430 Rattus norvegicus
378616 Xenopus laevis
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