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Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Zusätzlich bieten wir Ihnen Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antikörper (106) und Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteine (24) und viele weitere Produktgruppen zu diesem Protein an.
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Human CHI3L1 ELISA Kit für Sandwich ELISA - ABIN414711
Erfan, Guzel, Alpsoy, Rifaioglu, Kaya, Kucukyalc?n, Topcu, Kulac: Serum YKL-40: a potential biomarker for psoriasis or endothelial dysfunction in psoriasis? in Molecular and cellular biochemistry 2015
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Human CHI3L1 ELISA Kit für Sandwich ELISA - ABIN577524
Zhang, Peng, Cheng, Shi, Zhang, Xu: Paeoniflorin Atttenuates Amyloidogenesis and the Inflammatory Responses in a Transgenic Mouse Model of Alzheimer's Disease. in Neurochemical research 2015
The mouse model was used to validate the function of CHI3L1 in cancer metastasis in vivo
CHI3L1-mediated cell proliferation/survival involves partial downregulation of the pro-apoptotic S100A9 (zeige S100A9 ELISA Kits) protein that is highly expressed during the acute phase of colitis, by binding to the S100A9 (zeige S100A9 ELISA Kits) receptor, RAGE (zeige AGER ELISA Kits) (Receptor for Advanced Glycation End products).
IL-18 (zeige IL18 ELISA Kits) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (zeige IL18 ELISA Kits)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.
CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.
Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.
Results do not support a role of BRP (zeige GDF5 ELISA Kits)-39 in the pathogenesis of experimental autoimmune encephalitis.
CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.
mechanism of BRP (zeige GDF5 ELISA Kits)-39 in bleomycin-induced pulmonary fibrosis
Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis
Data show that IL-1 (zeige IL1A ELISA Kits)-induced transcriptin factor RelB (zeige RELB ELISA Kits)/NF-kappa B p50 (zeige NFKB1 ELISA Kits) Subunit complex formation was further promoted by oncostatin M (zeige OSM ELISA Kits) and that these complexes directly bound to the secreted protein cartilage glycoprotein 39 (YKL-40) promoter.
Study suggests that YKL-40 is associated with hypertension incidence only among men.
In HCT donors with YKL-40 plasma concentrations, a trend toward increased grade II-IV acute GvHD in recipients was observed with no significant associations with overall survival, treatment-related mortality or relapse
Review of evidence for the role of YKL-40 in the diagnosis, prognosis and cause of cardiovascular and alcoholic liver disease.
the level of CHI3L1 protein in the sera of patients with gastric or breast cancer was significantly elevated compared with those of healthy donors. M2 macrophage-secreted CHI3L1 promoted the metastasis of gastric and breast cancer cells in vitro and in vivo
Besides being associated with tau pathology, CSF (zeige CSF2 ELISA Kits) YKL-40 adds to the growing array of biomarkers reflecting distinct molecular brain mechanisms potentially useful for stratifying individuals for biomarker-guided, targeted anti-inflammatory therapies emerging from precision medicine.
SNPs in CHI3L1 and cord blood YKL-40 were not associated with lung function measurements at 5 weeks and 6 years, respiratory symptoms in the first year, and allergic sensitisation at 6 years. Genetic variation in CHI3L1 might be related to the development of milder forms of asthma.
Increased serum YKL-40 was related with poor collateral development and high SYNTAX score in patients with coronary artery disease.
Plasma YKL-40 and IL-6 (zeige IL6 ELISA Kits) had less diagnostic impact than CA 19.9
Findings show high level of both YKL-40 and GAP-43 (zeige GAP43 ELISA Kits) in CSF (zeige CSF2 ELISA Kits) of older women with suicidal ideation which suggest that a disrupted synaptic glial functioning and inflammation may be related to the aetiology of suicidal ideation in older adults.
fibroblast-derived Chi3L1 as a novel key player in the complex reciprocal interactions of stromal cells that facilitate tumor progression and metastasis.
chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
, cartilage glycoprotein 39
, chitinase-3-like protein 1
, 39 kDa synovial protein
, 38 kDa heparin-binding glycoprotein
, signal-processing protein
, 39 kDa whey protein
, 40 kDa secretory signalling glycoprotein
, cartilage glycoprotein-39
, chitinase-like protein 1
, signal processing protein
, chitinase 3-like 1 protein
, mammary gland protein 40