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Receptor for the C-X-C chemokine CXCL16.
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The expression of CXCR6 in tumor tissue may serve as a potential prognostic biomarker to refine clinical prognosis prediction combined with traditional clinical and pathological analysis for patients with clear cell renal cell carcinoma (ccRCC) after surgery.
Data showed that reverse signaling via CXCL16 (zeige CXCL16 ELISA Kits) promotes migration in CXCL16 (zeige CXCL16 ELISA Kits)-expressing melanoma and glioblastoma cells, but does not affect proliferation or protection from chemically-induced apoptosis.
Our results demonstrated that CXCR6 is an independent prognostic factor for poor survival in gastric cancer patients, and may promote gastric cancer metastasis through epithelial-mesenchymal transition.
In this study, we undertook a comprehensive comparison of CXCR6 gene variation in two South African populations (black and Caucasian) and investigated the possible association between two CXCR6 SNPs and different phenotypes of HIV-1 control in HIV-1-infected black South African individuals.
Our study demonstrated that CXCL16 (zeige CXCL16 ELISA Kits)-CXCR6 mediates CD8 (zeige CD8A ELISA Kits)(+) T-cell skin trafficking under oxidative stress in patients with vitiligo (zeige MITF ELISA Kits).
the DRF (zeige MPO ELISA Kits) motif of CXCR6 may display a receptor adaptation allowing adhesion and cell retention by transmembrane CXCL16 (zeige CXCL16 ELISA Kits) but reducing the chemotactic response to soluble CXCL16 (zeige CXCL16 ELISA Kits).
this study shows that CXCR6 mRNA levels in osteosarcoma tissues are higher than those in normal bone tissues
CXCR6 rs2234358 was associated with HCV spontaneous clearance and response to IFN-alpha/RBV therapy in Chinese Han population.
The expression level of CXCR6 was increased in gastric cancer.
The expression of CXCL16 (zeige CXCL16 ELISA Kits) and and its receptor, CXCR6, their immunolocalization in disc tissue and their presence following exposure of cultured human annulus fibrosus cells to proinflammatory cytokines are reported.
these results demonstrate an important role of CXCR6 in the regulation of pathological Th17 and IL-17A (zeige IL17A ELISA Kits)(+)TCRgammadelta(+) T-cell recruitment into atherosclerotic lesions.
CXCR6 has a role in the circulation of innate lymphoid cell precursors and their progeny
CXCR6 is essential for pressure overload-mediated myocardial recruitment of monocytes, which contributes to cardiac fibrosis through TNF-alpha (zeige TNF ELISA Kits)-dependent MMP9 (zeige MMP9 ELISA Kits) activation and collagen synthesis.
CXCR6 appears to influence long-term survival and tissue distribution of activated T cells.
CXCR6 deficiency inhibited total collagen deposition and suppressed the expression of collagen I and fibronectin (zeige FN1 ELISA Kits) in obstructed kidneys.
Intestinal ILC3s expressed CXCR6 and its ablation generated a selective loss of the NKp46 (zeige NCR1 ELISA Kits)(+) ILC3 subset, a depletion of intestinal IL-22 (zeige IL22 ELISA Kits), and the inability to control C. rodentium infection.
CXCR6 plays important roles in the pathogenesis of arthritis through its effects on both T cell cytokine polarization and homing of T cells to inflamed joints.
critical for the development and maintenance of protective memory CD8 (zeige CD8A ELISA Kits)+ T cells in the liver
CXCR6 plays a pivotal role in the development of Ang II (zeige AGT ELISA Kits)-induced renal injury and fibrosis through regulation of macrophage and T-cell infiltration and bone marrow-derived fibroblast accumulation.
CXCR6, the receptor for CXCL16 (zeige CXCL16 ELISA Kits), is critically involved in the pathogenesis of myocardial remodeling and development of heart failure following ischemia/reperfusion injury.
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
C-X-C chemokine receptor type 6
, chemokine C-X-C motif receptor 6
, G protein-coupled receptor TYMSTR
, chemokine (C-X-C motif) receptor 6
, G protein-coupled receptor
, G-protein coupled receptor STRL33
, G-protein coupled receptor bonzo
, chemokine receptor CXCR6
, G protein-coupled receptor STRL33
, chemokine receptor bonzo