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CXCR5 encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family.
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Human CXCR5 ELISA Kit für Sandwich ELISA - ABIN417542
Og?odek, Szota, Just, Mo?, Araszkiewicz: Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression. in Pharmacological reports : PR 2014
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The A allele of rs613791 and G allele of rs523604 located in CXCR5 were observed to be significantly associated with vitiligo in the Chinese Han population.
These results provide clear evidence that CXCR4- or CCR5-beta-arrestin complexes induce receptor endocytosis and signaling in the absence of G protein coupling and ligand-induced conformational changes of the receptor.
these findings demonstrate that CXCR5 overexpression increases the ability of MSCs to respond to migratory stimuli and highly intensifies their immunomodulatory effects in vivo. This strategy for enhancing targeted stem/progenitor cell homing may improve the efficacy of MSC (zeige MSC ELISA Kits)-based therapies.
all three p53 (zeige TP53 ELISA Kits) family members mediate the effects of genotoxic stress on the CXCR5 promoter using the same mechanism associated with attenuation of NFkB activity.
identified the miR (zeige MLXIP ELISA Kits)-19a/CXCR5 pathway as a candidate p53 (zeige TP53 ELISA Kits)-induced migration mechanism
CXCL13 (zeige CXCL13 ELISA Kits)/CXCR5 mediated the aggregation of B cells, that directed the aberrant humoral immune responses via the formation of ectopic germinal centers, which suggests a molecular mechanism of neurological damage in neurosyphilis.
the data demonstrate that CXCR5(+)CD8 (zeige CD8A ELISA Kits)(+) T cells represent a significant CD8 (zeige CD8A ELISA Kits)(+) T cell subset in colorectal tumors and have the potential to contribute to antitumor immunity, but their specific roles require further studies in vivo.
we demonstrate that PKCepsilon (zeige PRKCE ELISA Kits) cooperates with the loss of the tumor suppressor Pten for the development of prostate cancer in a mouse model. Mechanistic analysis revealed that PKCe (zeige PRKCE ELISA Kits) overexpression and Pten loss individually and synergistically upregulate the production of the chemokine (zeige CCL1 ELISA Kits) CXCL13 (zeige CXCL13 ELISA Kits), which involves the transcriptional activation of the CXCL13 (zeige CXCL13 ELISA Kits) gene
Levels of CXCR5 mRNA and protein levels were up-regulated in brain from temporal lobe epilepsy patients.
Neoplastic cells of PCSM-TCL are medium- to-large-sized T cells with cerebriform nuclei, which lack the expression of TFH-cell defining chemokine receptor CXCR5. These features are highly distinctive and can be invaluable in separating this rather indolent cutaneous T-cell lymphoid neoplasm from more aggressive lymphomas of TFH-cell phenotype, including primary cutaneous TFH-cell lymphoma and skin involvement of AITL
CXCL13 (zeige CXCL13 ELISA Kits) acts on CXCR5 to increase p38 (zeige CRK ELISA Kits) activation and further contributes to the pathogenesis of orofacial neuropathic pain
Cxcr5(CreERT2)R26(Tomato) mice are a useful tool for studying the cell fate of differentiated follicular helper T cells in vivo
CXCL13 (zeige CXCL13 ELISA Kits) and CXCR5 contribute to orofacial pain via ERK (zeige EPHB2 ELISA Kits)-mediated proinflammatory cytokines production.
Cxcr5 role in the protection of retinal pigment epithelium and retinal cells during aging and Cxcr5 loss may lead to age-related macular degeneration like pathological changes in aged mice.
These data suggest that CXCR5-expressing conventional dendritic cells play an important role in the efficient propagation of orally administered prions toward follicular dendritic cells within Peyer's patches in order to establish host infection.
CXCR5 is involved critically in B cell trafficking and germinal cell formation in murine lupus and in guiding pathogenic double-negative T cells into lymphoid organs and kidneys.
The importance of CXCR5 in autoimmune arthritis varies depending on environmental circumstances.
findings reveal a neuronal/astrocytic interaction in the spinal cord by which neuronally produced CXCL13 (zeige CXCL13 ELISA Kits) activates astrocytes via CXCR5 to facilitate neuropathic pain.
IL-33 (zeige IL33 ELISA Kits) enhances humoral immunity against chronic hbv infection through activating CD4 (zeige CD4 ELISA Kits)(+)CXCR5(+) helper-Inducer T-Lymphocytes.
Results identify p66Shc (zeige SHC1 ELISA Kits) as a negative regulator of B-cell chemotaxis and suggest a role for this adaptor in the control of B-cell homing via CXCR4 (zeige CXCR4 ELISA Kits)/5.
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
, C-X-C chemokine receptor type 5
, chemokine receptor
, Burkitt lymphoma receptor 1
, chemokine (C-X-C motif) receptor 5
, c-X-C chemokine receptor type 5-like
, Burkitt lymphoma receptor 1, GTP-binding protein
, monocyte-derived receptor 15
, burkitt lymphoma receptor 1 homolog
, chemochine (C-X-C motif) receptor 5
, neurolymphatic receptor