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Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Zusätzlich bieten wir Ihnen CXCL16 Antikörper (198) und CXCL16 Proteine (45) und viele weitere Produktgruppen zu diesem Protein an.
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Mouse (Murine) CXCL16 ELISA Kit für Sandwich ELISA - ABIN625119
Zeng, See, Phallen, Jackson, Belcaid, Ruzevick, Durham, Meyer, Harris, Albesiano, Pradilla, Ford, Wong, Hammers, Mathios, Tyler, Brem, Tran, Pardoll, Drake, Lim: Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. in International journal of radiation oncology, biology, physics 2013
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Mouse (Murine) CXCL16 ELISA Kit für Sandwich ELISA - ABIN2683996
Matloubian, David, Engel, Ryan, Cyster: A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. in Nature immunology 2001
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Data indicate that chemokine (zeige CCL1 ELISA Kits) C-X-C ligand 16 (CXCL16) is a critical regulator of liver immune response to acetaminophen (APAP)-induced hepatotoxicity, suggesting a potential strategy for the treatment of drug-induced acute liver failure by targeting CXCL16.
CXCL16 plays a crucial role in the pathogenesis of cisplatin-induced acute kidney injury through regulation of apoptosis and inflammation.
These findings suggest that the CXCL16 gene product promotes inflammatory factors and cell infiltration factors, and inhibits the expression of antioxidant factors to accelerate the development of DN, and CXCL16 deficiency attenuates DN may be involved in the AKT (zeige AKT1 ELISA Kits) signaling pathway.
Results indicate that CXCL16 plays a pivotal role in the pathogenesis of renal artery stenosis-induced renal injury and fibrosis through regulation of bone marrow-derived fibroblast accumulation and macrophage and T-cell infiltration.
Simvastatin exerts a protective effect on renal function and structure in mice with ADR nephropathy which related to the decreasing expression of CXCL16 in glomerular podocytes followed by the decreasing endocytosis of ox-LDL in podocytes and inhibition of NF-kappaB (zeige NFKB1 ELISA Kits) pathway activation.
These results indicate that MEK (zeige MDK ELISA Kits) inhibitor diminishes Nasopharyngeal carcinoma cell proliferation and NPC (zeige NPC1 ELISA Kits)-induced osteoclastogenesis via modulating CCL2 (zeige CCL2 ELISA Kits) and CXCL16 expressions.
Serum CXCL16 is increased in severe pancreatitis with infected pancreatic necrosis and identifies patients who benefit from surgical necrosectomy
injured hepatocytes up-regulated CXCL16 expression, indicating that scavenging functions of CXCL16 might be additionally involved in the pathogenesis of NAFLD (zeige TSC2 ELISA Kits).
role of IFN-gamma (zeige IFNG ELISA Kits), CXCL16, and ADAM10 (zeige ADAM10 ELISA Kits) in oxLDL-induced lipid accumulation in glomerular podocytes
CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-alpha (zeige TNF ELISA Kits)-induced apoptosis by tumor-associated macrophages.
Women with gestational diabetes mellitus and preeclampsia had a dysregulated CXC chemokine ligand 16 during pregnancy, and in gestational diabetes mellitus, the increase in CXC chemokine ligand 16 early in pregnancy and after 5 years was strongly associated with their lipid profile.
Data suggest that primary cells from papillary renal cell carcinoma secrete the chemokines IL8 (zeige IL8 ELISA Kits), CXCL16, and chemerin (zeige RARRES2 ELISA Kits); these chemokines attract primary human monocytes and induce shift/transdifferentiation in monocytes toward M2 macrophage/foam cell phenotype. (IL8 (zeige IL8 ELISA Kits) = interleukin-8 (zeige IL8 ELISA Kits); CXCL16 = C-X-C motif chemokine (zeige CCL1 ELISA Kits) ligand 16)
Our study demonstrated that CXCL16-CXCR6 (zeige CXCR6 ELISA Kits) mediates CD8 (zeige CD8A ELISA Kits)(+) T-cell skin trafficking under oxidative stress in patients with vitiligo (zeige MITF ELISA Kits), and CXCL16 expression in human keratinocytes induced by ROS (zeige ROS1 ELISA Kits) is, at least in part, caused by unfolded protein response activation
eGFR (zeige EGFR ELISA Kits) and serum albumin (zeige ALB ELISA Kits) had an independent and significant negative correlation with plasma CXCL16 in diabetic kidney disease.
The expression of CXCL16 and and its receptor, CXCR6 (zeige CXCR6 ELISA Kits), their immunolocalization in disc tissue and their presence following exposure of cultured human annulus fibrosus cells to proinflammatory cytokines are reported.
Inflammation contributed to foam cell formation in the radial arteries of ESRD patients via activation of the CXCL16/CXCR6 (zeige CXCR6 ELISA Kits) pathway, which may be regulated by P2X7R (zeige P2RX7 ELISA Kits).
CXCL16 single nucleotide polymorphisms significantly impacted myocardial infarction risk in a Chinese Han population.
Transmembrane-CXCL16 specifically acts as a receptor for soluble-CXCL16 in human meningioma cells.
Higher levels CXCL16 may be a biomarker for predicting stroke incidence and might contribute to plaque destabilization.
CXCL16 is released into the circulation as a result of cardiac surgery and that high post-operative CXCL16 levels are associated with an increased severity of post-operative organ dysfunctions.
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
chemokine (C-X-C motif) ligand 16
, C-X-C motif chemokine 16
, Transmembrane chemokine CXCL16
, Cxc chemokine ligand 16
, scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
, small-inducible cytokine B16
, transmembrane chemokine CXCL16
, zinc finger, MYND-type containing 15
, CXC chemokine ligand 16