Chemokine (C-C Motif) Receptor 9 Proteine (CCR9)

The protein encoded by CCR9 is a member of the beta chemokine receptor family. Zusätzlich bieten wir Ihnen Chemokine (C-C Motif) Receptor 9 Antikörper (182) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CCR9 10803 P51686
CCR9 12769 Q9WUT7
Ratte CCR9 CCR9 282832  
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,493.38
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,262.31
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Wheat germ Human Unkonjugiert   2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$469.02
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Escherichia coli (E. coli) Maus Unkonjugiert   50 μg Anmelden zum Anzeigen 9 bis 11 Tage
$310.00
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CCR9 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Mouse (Murine) ,

Weitere Proteine zu Chemokine (C-C Motif) Receptor 9 (CCR9) Interaktionspartnern

Human Chemokine (C-C Motif) Receptor 9 (CCR9) Interaktionspartner

  1. There were significantly increased CCR9 protein levels in failing human hearts.

  2. this study showed that CCR7 are overexpressed in CD4(-) CD8(-) thymocytes of myasthenia gravis patients.

  3. Results indicated that the expression levels of CCR9 in lesional skin may be a useful biologic marker of the clinical efficacy of infliximab therapy in psoriasis patients.

  4. Xray crystal structure of the CCR9 receptor in complex with vercirnon at 2.8 A resolution

  5. It plays a pathogenic role in liver diseases and it will be a therapeutic target of the diseases.

  6. that CCL25/CCR9 signal may provide cancer cells with chemotactic abilities through influencing several epithelial-mesenchymal transitionmarkers

  7. Studies indicate important roles played by chemokine ligand 25 (CCL25)/chemokine receptor 9 (CCR9) in tumorigenesis, tumor chemoresistance and metastasis.

  8. CCR9 and Integrin-beta7 expression has a differential effect on graft fate during acute graft-versus-host disease (GVHD) of the liver depending on the GVHD target tissue.

  9. CCR9 mRNA and protein levels were significantly increased in the nasopharyngeal carcinoma group compared with the control group.

  10. CCR9-CCL25 interaction promoted proliferation and suppressed apoptosis of non-small cell lung cancer cells by activating the PI3K/Akt pathway.

  11. CCR9 could be beneficial in predicting lymph node metastasis, and it might act as a novel prognostic biomarker for lung adenocarcinoma.

  12. We also show that primary tumors can be modeled in immunocompetent mice by microinjecting CCR9-expressing cancer cell lines into early-stage mouse blastocysts, which induces central immune tolerance

  13. High CCR9 expression is associated with the pathogenesis of ulcerative colitis.

  14. Expression of CCR9 and CCL25, the only natural ligand of CCR9, was significantly higher (p<0.0001) in NSCLC tissues and serum respectively, compared to their respective controls.

  15. activation of Notch1 has a dominant-negative effect on Ccr9 transcription and that Notch1 and E proteins control the dynamic expression of Ccr9 during T cell development.

  16. The results show the potential of the 91R monoclonal antibody as a therapeutic agent for treatment of CCR9-expressing tumors.

  17. results suggest that CCR9 can act as a novel prognostic marker and therapeutic target for hepatocellular carcinoma

  18. CCR9 expression is elevated in the nodal lymphomas of patients with GI involvement

  19. Only rotavirus specific CD4 T cells expressed intestinal homing receptors alpha4beta7 and CCR9.

  20. Data suggest that P-glycoprotein associate with the F-actin cytoskeleton through ezrin/radixin/moesin (ERM) in CCR9/CCL25 induced multidrug resistance of acute T-lymphocytic leukemia (T-ALL) cells.

Mouse (Murine) Chemokine (C-C Motif) Receptor 9 (CCR9) Interaktionspartner

  1. these results showed a site- and cell-specific expressions of Ccl25 and its receptor Ccr9 within both maternal and embryonic compartments of implantation sites and suggested a role in inducing specific Ccr9+ leukocytes at the maternal-fetal interface during the initial steps of embryo implantation in the mouse model

  2. Abrogation of CCR9 improved the post-myocardial infarction survival rate and left ventricular (LV) dysfunction and decreased the infarct size. The data reveal that CCR9 serves as a novel modulator of pathological progression following myocardial infarction through NF-kappaB and MAPK signaling.

  3. Pressure overload-induced hypertrophy was greatly attenuated by CCR9 deficiency in cardiac-specific CCR9 knockout mice, whereas CCR9 overexpression in cardiac-specific transgenic mice strikingly enhanced cardiac hypertrophy.

  4. CCR9 and CCL25 expressions are induced in the early stages of airway inflammation and they have an important role modulating eosinophils and lymphocytes recruitment at the first stages of inflammatory process

  5. CCR9 and Integrin-beta7 expression has a differential effect on graft fate during acute graft-versus-host disease (GVHD) of the liver depending on the GVHD target tissue.

  6. data indicate that in addition to acting as a gut-homing molecule, CCR9 signaling shapes immune responses by inhibiting Treg cell development

  7. Data suggest that blocking CC chemokine receptor 9 (CCR9) may represent a novel safe therapy for rheumatoid arthritis (RA).

  8. activation of Notch1 has a dominant-negative effect on Ccr9 transcription and that Notch1 and E proteins control the dynamic expression of Ccr9 during T cell development.

  9. CCR9/CCL25 is involved in acute skin transplantation rejection and anti-CCL25 strategies might be useful in preventing acute rejection.

  10. Accumulated CD11b(+) macrophages are critical for activating hepatic stellate cells through the CCR9/CCL25 axis and therefore promote liver fibrosis.

  11. CCR9-expressed plasmacytoid dendritic cells are possibly small intestine regulatory, antigen-presenting cells that suppress intestinal inflammation.

  12. CCR9 is required for recruitment of peritoneal macrophages in the steady state to control systemic sepsis during early phases of peritoneal infection.

  13. Data show that chemokine receptor CCR9(-/-) knockout mice developed a chronic inflammatory response with over-expression of the cytokines and chemokines.

  14. characterization of expression and thymus-expressed chemokine responsiveness of the murine thymus, spleen and mesenteric lymph node

  15. CCR9(+) macrophages contribute to the induction of acute liver inflammation in mouse models of hepatitis.

  16. CCL25/CCR9 interactions regulate inflammatory immune responses in the large intestinal mucosa by balancing different subsets of dendritic cells.

  17. Three chemokine receptors, Ccr9, Ccr7, and Cxcr4, cooperatively regulate homing of hematopoietic progenitors to the embryonic mouse thymus.

  18. Signaling of the chemokine CCL25 through its receptor CCR9 induces Tregs to migrate to the intestine.

  19. CCR9+ Th cells are a subset of IL-21-producing T helper cells that influence regional specification of autoimmune diseases that affect accessory organs of the digestive system

  20. Critical role of chemokine receptor signaling in thymic settling.

Chemokine (C-C Motif) Receptor 9 (CCR9) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CCR9

  • C-C motif chemokine receptor 9 (CCR9)
  • chemokine (C-C motif) receptor 9 (Ccr9)
  • C-C motif chemokine receptor 9 (Ccr9)
  • A130091K22Rik Protein
  • CC-CKR-9 Protein
  • CDw199 Protein
  • Cmkbr10 Protein
  • GPR-9-6 Protein
  • GPR28 Protein

Bezeichner auf Proteinebene für CCR9

C-C chemokine receptor type 9 , G protein-coupled receptor 28 , C-C CKR-9 , CC-CKR-9 , CCR-9 , chemokine C-C receptor 10 , chemokine C-C motif receptor 9

GENE ID SPEZIES
10803 Homo sapiens
12769 Mus musculus
484793 Canis lupus familiaris
100065535 Equus caballus
530951 Bos taurus
678667 Ovis aries
282832 Rattus norvegicus
713934 Macaca mulatta
414377 Sus scrofa
Ausgewählte Anbieter für Chemokine (C-C Motif) Receptor 9 Proteine (CCR9)
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