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CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Zusätzlich bieten wir Ihnen CCL22 Antikörper (245) und CCL22 Proteine (61) und viele weitere Produktgruppen zu diesem Protein an.
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Human CCL22 ELISA Kit für Sandwich ELISA - ABIN625044
Shi, Song, Xiong, Cao, Liao, Ma, Zhang, Zeng, Liu, Wang, Cui, Huang, Liu: Disease-specific T-helper cell polarizing function of lesional dendritic cells in different types of chronic rhinosinusitis with nasal polyps. in American journal of respiratory and critical care medicine 2014
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Human CCL22 ELISA Kit für Sandwich ELISA - ABIN365803
García, Cidoncha, Bote, Hinchado, Ortega: Altered profile of chemokines in fibromyalgia patients. in Annals of clinical biochemistry 2014
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Human CCL22 ELISA Kit für Sandwich ELISA - ABIN411323
Godiska, Chantry, Raport, Sozzani, Allavena, Leviten, Mantovani, Gray: Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. in The Journal of experimental medicine 1997
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blood CCL22 levels were positively associated with IgE sensitization at age 2. A high cord blood CCL22/CXCL10 (zeige CXCL10 ELISA Kits) chemokine (zeige CCL1 ELISA Kits) ratio was significantly associated with a higher risk of allergic sensitization at age 3.
Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22-CCR4 (zeige CCR4 ELISA Kits) signaling axis.
Elevations in serum MDC (zeige ADAM11 ELISA Kits) and BLC (zeige CXCL13 ELISA Kits) were independently associated with the significant risk of early stage lung adenocarcinoma, even in non-smokers and in stage IA patients.
These results showed that the higher levels of CXCL10 (zeige CXCL10 ELISA Kits), CCL20 (zeige CCL20 ELISA Kits) and CCL22 were associated with ischemic heart disease. The serum levels of chemokines may influence by the certain traditional risk factors of IHD and some studied SNPs, but did not influence by treatment and gender of patients.
CCL22 plays an important role in supporting gastric cancer development presumably by increasing the percentage of regulatory T cells in the tumor microenvironments. CCL22 levels in sera have a predictive value for gastric cancer peritoneal metastasis and the early recurrence.
The CCL22-mediated enhancement of antitumor responses is however not due to conversion, but rather to redirection of existing regulatory T cells to the site of cutaneous overexpression.
CCL22 and IL-37 with a co-localization in non-small cell lung cancer A549 cells inhibited the proliferation and epithelial-mesenchymal transition process
Data suggest that Th1 (zeige TH1L ELISA Kits) (IFN-gamma (zeige IFNG ELISA Kits)-inducible protein-10 IP-10/CXCL10 (zeige CXCL10 ELISA Kits)) and Th2 (thymus and activation regulated chemokine TARC/CCL17 (zeige CCL17 ELISA Kits)) and (macrophage derived chemokine MDC/CCL22) cooperatively play a role in the development of ankylosing spondylitis (AS).
Our results demonstrate that CCL22 is expressed in human placenta. Decidual expression was only observed in miscarriage conditions and correlates with Treg infiltration.
Distinctive Treg associated CCR4 (zeige CCR4 ELISA Kits)-CCL22 expression profile with altered frequency of Th17/Treg cell in the immunopathogenesis of Pemphigus Vulgaris (zeige DSG3 ELISA Kits).
Intratumoral administration of anti-CCL22 antibody inhibited B16F10 melanoma growth.
this study shows that intravenous injection of apoptotic cells induces a subsequent increase in CCL22 expression and CCR4+ Treg cells, which contribute to the maintenance of immune homeostasis at least partially by splenic CD8alpha+ CD103+ dendritic cells
CCL22-specific antibodies reveal that engagement of two distinct binding domains on CCL22 is required for CCR4 (zeige CCR4 ELISA Kits)-mediated function.
CCL22 was localised mainly on the cell surface and or in the cytoplasm. Within sections of omental milky spot micrometastases, CCR4 (zeige CCR4 ELISA Kits) was recognised on or in gastric cancer cells, constituent cells milky spots, blood cells and blood endothelial cells
results show that the IL-4 (zeige IL4 ELISA Kits)/CCL22/CCR4 (zeige CCR4 ELISA Kits) axis is involved in the migration of Tregs to osteolytic lesion sites, and attenuates development of lesions by inhibiting inflammatory migration and the production of proinflammatory and osteoclastogenic mediators
CCL22 has a role in Treg skin homing to suppress depigmentation
CCL22 is a novel mediator of lung inflammation following hemorrhage and resuscitation
The immunomodulatory properties of CCL22 could be harnessed for prevention of graft rejection and type 1 diabetes as well as other autoimmune disorders.
Data indicate macrophage-derived chemokine CCL22 as an adjuvant could enhance the immune protective effect of NTHi-P6 protein vaccine to an extent.
islet expression of CCL22 recruits Tregs and attenuates autoimmune destruction of beta cell
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
C-C motif chemokine 22
, CC chemokine STCP-1
, macrophage-derived chemokine
, small inducible cytokine A22
, small inducible cytokine subfamily A (Cys-Cys), member 22
, small-inducible cytokine A22
, stimulated T cell chemotactic protein 1
, stimulated T-cell chemotactic protein 1
, CC chemokine ABCD-1
, SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED)
, activated B and dendritic cell-derived
, dendritic cell and B cell derived chemokine
, small inducible cytokine subfamily A, member 22
, small inducible cytokine subfamily A22
, small inducible cytokine subfamily A (Cys-Cys) member 22
, chemokine (C-C motif) ligand 22