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CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17.
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Human CCL18 ELISA Kit für Sandwich ELISA - ABIN2683652
Genin, Clement, Fattaccioli, Raes, Michiels: M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide. in BMC cancer 2015
All patients with NPC1 (zeige NPC1 ELISA Kits) mutations had high ChT (zeige ChT ELISA Kits) activity, high CCL18/PARC concentrations and/or Niemann-Pick disease type C suspicion index scores >/=70.
findings suggest that these pulmonary markers could be useful to assess CAP severity and, especially YKL-40 (zeige CHI3L1 ELISA Kits) and CCL18 by helping predict CAP caused by atypical pathogens
PARC (zeige CUL9 ELISA Kits) activation of neutrophils by sterile immunogenic dying cells drives neutrophil-mediated residual cell killing.
Matrigel invasion assays revealed that tumor ECM (zeige MMRN1 ELISA Kits)-educated macrophages efficiently stimulated cancer cell invasion through a mechanism involving CCL18.
Our results indicate that CCL18 acts in an autocrine manner via Akt (zeige AKT1 ELISA Kits) activation to stimulate oral squamous cell carcinoma cell growth and invasion during disease progression
Our data indicate that hypoxic inhibition of JMJD3 (zeige Kdm6b ELISA Kits) activity reduces demethylation of H3K27me3, nucleosome removal, and hence induction of the STAT6 (zeige STAT6 ELISA Kits) target gene CCL18, while induction of other STAT6 (zeige STAT6 ELISA Kits)-inducible genes such as SPINT2 (zeige SPINT2 ELISA Kits) remained unaffected by JMJD3 (zeige Kdm6b ELISA Kits).
There was no association between serial CCL18 concentrations with tumor response and overall survival.
CCL-18 is a promising biomarker in COPD (zeige ARCN1 ELISA Kits), as it is associated with frequency of exacerbations, particularly with severe COPD (zeige ARCN1 ELISA Kits) exacerbations requiring hospitalization, as well as with functional parameters and symptom scores.
Data suggested that CCL18 upregulated Slug expression to promote epithelial-mesenchymal transition (EMT (zeige ITK ELISA Kits)) and stem cell-like features by activating the mTOR (zeige FRAP1 ELISA Kits) pathway in oral cancer.
An increased lung protein expression of PARC (zeige CUL9 ELISA Kits) in chronic obstructive pulmonary disease patients
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.
C-C motif chemokine 18
, CC chemokine PARC
, CC chemokine ligand 18
, alternative macrophage activation-associated CC chemokine 1
, chemokine (C-C), dendritic
, dendritic cell chemokine 1
, macrophage inflammatory protein 4
, pulmonary and activation-regulated chemokine
, small inducible cytokine A18
, small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated
, small-inducible cytokine A18
, chemokine CCL18/PARC