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CCL15 is located in a cluster of similar genes in the same region of chromosome 17. Zusätzlich bieten wir Ihnen CCL15 Antikörper (104) und CCL15 Kits (50) und viele weitere Produktgruppen zu diesem Protein an.
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CCL15 secreted from SMAD4 (zeige SMAD4 Proteine)-deficient xenografted human colorectal cancer cells recruited CCR1(+) cells, promoting their metastatic activities to the lung. Lung metastases from colorectal cancer patients revealed that CCL15 expression correlated with loss of SMAD4 (zeige SMAD4 Proteine). CCL15-positive metastases recruited approximately 1.9 times more numbers of CCR1(+) cells than CCL15-negative metastases.
CCL15 activation of CCR1 plays critical roles in hepatocellular carcinoma metastasis.
Orthotopic animal models of HCC (zeige FAM126A Proteine) were established to investigate the role of CCL15 in hMSCs migration toward HCC (zeige FAM126A Proteine) in vivo. Both histological and flow cytometric analysis showed that significantly fewer hMSCs localized within 97H-CCL15-shRNA xenografts compared with 97H-green fluorescent protein xenografts after intravenous delivery
Loss of SMAD4 (zeige SMAD4 Proteine) was significantly associated with CCL15 expression.
follicular thyroid carcinoma (FTC (zeige FUT2 Proteine)) might induce tumor associated macrophages (TAMs) infiltration by producing CCL15. Measurement of TAMs and CCL15 in follicular thyroid lesions may be applied clinically to differentiate FTC (zeige FUT2 Proteine) from follicular adenoma
two inflammatory cytokines, MIP (zeige TNPO1 Proteine)-1delta and MIP-3alpha (zeige CCL20 Proteine), are able to increase mesenchymal stromal cells migration in vitro
we investigated a role of CCL15 in upregulating ICAM-1 (zeige ICAM1 Proteine) in endothelial cells
CCL15 is elevated in human asthma and correlates with disease severity .
Data show that Only three of these proteins EGF (zeige EGF Proteine), PDGF (zeige PDGFA Proteine)-BB and MIP (zeige TNPO1 Proteine)-1delta (CCL15) differed significantly in plasma between controls and Alzheimer's disease (AD).
PKCdelta (zeige PKCd Proteine) activation due to Lkn-1 is involved in migration, as well as the butyric acid-induced differentiation.
This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14).
C-C motif chemokine 15
, chemokine CC-2
, leukotactin 1
, macrophage inflammatory protein 5
, new CC chemokine 3
, small inducible cytokine subfamily A (Cys-Cys), member 15
, small-inducible cytokine A15