Chemokine (C-C Motif) Ligand 15 Proteine (CCL15)

CCL15 is located in a cluster of similar genes in the same region of chromosome 17. Zusätzlich bieten wir Ihnen CCL15 Antikörper (100) und CCL15 Kits (49) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CCL15 6359 Q16663
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Top CCL15 Proteine auf

Showing 10 out of 35 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Escherichia coli (E. coli) Human Unkonjugiert   10 μg Anmelden zum Anzeigen 10 bis 12 Tage
Escherichia coli (E. coli) Human Unkonjugiert Validation with Western Blot 25 μg Anmelden zum Anzeigen 8 bis 11 Tage
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 14 bis 16 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human MIP5 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
Escherichia coli (E. coli) Human Unkonjugiert   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
Escherichia coli (E. coli) Human Unkonjugiert   0.005 mg Anmelden zum Anzeigen 2 bis 3 Tage
Escherichia coli (E. coli) Human Unkonjugiert   25 μg Anmelden zum Anzeigen 9 bis 11 Tage

CCL15 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,

Weitere Proteine zu Chemokine (C-C Motif) Ligand 15 (CCL15) Interaktionspartnern

Human Chemokine (C-C Motif) Ligand 15 (CCL15) Interaktionspartner

  1. CCL15 secreted from SMAD4-deficient xenografted human colorectal cancer cells recruited CCR1(+) cells, promoting their metastatic activities to the lung. Lung metastases from colorectal cancer patients revealed that CCL15 expression correlated with loss of SMAD4. CCL15-positive metastases recruited approximately 1.9 times more numbers of CCR1(+) cells than CCL15-negative metastases.

  2. CCL15 activation of CCR1 plays critical roles in hepatocellular carcinoma metastasis.

  3. Orthotopic animal models of HCC were established to investigate the role of CCL15 in hMSCs migration toward HCC in vivo. Both histological and flow cytometric analysis showed that significantly fewer hMSCs localized within 97H-CCL15-shRNA xenografts compared with 97H-green fluorescent protein xenografts after intravenous delivery

  4. Loss of SMAD4 was significantly associated with CCL15 expression.

  5. follicular thyroid carcinoma (FTC) might induce tumor associated macrophages (TAMs) infiltration by producing CCL15. Measurement of TAMs and CCL15 in follicular thyroid lesions may be applied clinically to differentiate FTC from follicular adenoma

  6. two inflammatory cytokines, MIP-1delta and MIP-3alpha, are able to increase mesenchymal stromal cells migration in vitro

  7. we investigated a role of CCL15 in upregulating ICAM-1 in endothelial cells

  8. CCL15 is elevated in human asthma and correlates with disease severity .

  9. Data show that Only three of these proteins EGF, PDGF-BB and MIP-1delta (CCL15) differed significantly in plasma between controls and Alzheimer's disease (AD).

  10. PKCdelta activation due to Lkn-1 is involved in migration, as well as the butyric acid-induced differentiation.

  11. increased secretion by macrophages during Mycobacterium tuberculosis infection

  12. enhanced expression in intestinal epithelium in inflammatory bowel disease and display of antibacterial activity

  13. truncation of NH2-terminal amino acid residues increases agonistic potency on CC chemokine receptors 1 and 3

  14. Lkn-1 activates the ERK pathway by transducing the signal through G(i)/G(o) protein, PLC, PKC delta and Ras, and it may play a role for cell proliferation, differentiation, and regulation of gene expression for other cellular processes

  15. These observations demonstrate that the two NF-kappaB binding sites are essential for phorbol myristate acetate-induced leukotactin-1 (Lkn-1)/CCL15 expression in human monocytes.

  16. CCL15(25-92) has in vitro and in vivo angiogenic activity

  17. alanine-aspartic acid residues preceding the first cysteine at the NH(2)-terminus are essential for the binding and biological activity of leukotactin-1

  18. Compared with full-length CCL15, proteolytically processed CCL15 isoforms with N-terminal deletions display increased potency to induce calcium fluxes and chemotactic activity on monocytes and to induce adhesiveness of mononuclear cells to fibronectin.

  19. Transcription of the CCL15 gene is regulated by AP-1 and NF-kappaB through MEK and JNK MAPK pathways in monocytoid cells.

  20. Results point to an involvement of the CCL15-CCR1 axis in the pathophysiology of chronic renal failure.

CCL15 Protein Überblick

Protein Überblick

This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14).

Genbezeichner und Symbole assoziert mit CCL15

  • C-C motif chemokine ligand 15 (CCL15)
  • HCC-2 Protein
  • HMRP-2B Protein
  • LKN-1 Protein
  • LKN1 Protein
  • MIP-1 delta Protein
  • MIP-1D Protein
  • MIP-5 Protein
  • MRP-2B Protein
  • NCC-3 Protein
  • NCC3 Protein
  • SCYA15 Protein
  • SCYL3 Protein
  • SY15 Protein

Bezeichner auf Proteinebene für CCL15

C-C motif chemokine 15 , chemokine CC-2 , leukotactin 1 , macrophage inflammatory protein 5 , new CC chemokine 3 , small inducible cytokine subfamily A (Cys-Cys), member 15 , small-inducible cytokine A15

6359 Homo sapiens
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