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Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity). Zusätzlich bieten wir Ihnen Chaperonin GroEL Antikörper (25) und viele weitere Produktgruppen zu diesem Protein an.
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HSP60 (zeige HSPD1 Proteine) showed pro-inflammatory properties in bronchial epithelial cells mediated by activation of TLR-4 (zeige TLR4 Proteine)-related molecules.
HSP60 (zeige HSPD1 Proteine) silencing deactivates the mTOR (zeige FRAP1 Proteine) pathway to suppress glioblastoma progression
the effect of Hsp60 (zeige HSPD1 Proteine) on differentiation and invasion of hepatocellular carcinoma cells might be associated with mitochondrial biogenesis
The results demonstrate that HSP60 (zeige HSPD1 Proteine) participates in mitochondrial progesterone synthesis. These findings provide novel insights into progesterone synthesis in the human placenta and its role in maintaining pregnancy.
Clinical data showed that upregulation of miR (zeige MLXIP Proteine)-382/3-NT and downregulation of HSPD1 (zeige HSPD1 Proteine)/Trx (zeige VAC14 Proteine) were also observed in IgA nephropathy patients with renal interstitial fibrosis. These data supported a novel mechanism in which miR (zeige MLXIP Proteine)-382 targets HSPD1 (zeige HSPD1 Proteine) and contributes to the redox imbalance in the development of renal fibrosis.
Low HSP60 (zeige HSPD1 Proteine) expression is associated with beta-cell hypertrophy and dysfunction.
high level of ROS (zeige ROS1 Proteine) is needed for tumorigenesis and progression in tumors with low HSP60 (zeige HSPD1 Proteine) expression
HSP60 (zeige HSPD1 Proteine) regulation of SOX9 (zeige SOX9 Proteine) ubiquitination mitigates the development of knee osteoarthritis.
These findings shed some light on how a tumor cell may avert apoptosis using Hsp60 (zeige HSPD1 Proteine) and point to the anti-cancer potential of drugs, such as CubipyOXA, which interfere with Hsp60 (zeige HSPD1 Proteine)/pC3 (zeige PCSK1 Proteine) complex formation, and thus allow the apoptotic cascade to proceed.
The associations of diabetes, combined with the polymorphisms in the genes of fat mass and obesity-associated (zeige FTO Proteine) gene (FTO (zeige FTO Proteine)), interleukin 6 (IL-6 (zeige IL6 Proteine)), and heat shock protein 60 (HSPD1 (zeige HSPD1 Proteine)), with breast cancer risk and survival in a Chinese Han population, was evaluated.
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
60 kDa chaperonin
, 60 kDa heat shock protein, mitochondrial
, P60 lymphocyte protein
, chaperonin 60
, heat shock protein 65
, mitochondrial matrix protein P1
, short heat shock protein 60 Hsp60s1
, chaperonin GroEL
, molecular chaperone GroEL