anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) Antikörper

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Zusätzlich bieten wir Ihnen CCAR2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CCAR2 57805 Q8N163
CCAR2    
CCAR2    
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Showing 10 out of 50 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of KIAA1967 expression in A549 (A), HeLa (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using CCAR2 antibody (ABIN5974285) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human kidney using CCAR2 antibody (ABIN5974285) at dilution of 1/100 (40x lens). 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from Jurkat cells, using KIAA1967 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to KIAA1967 on HeLa cell (antibody concentration 10 µg/mL). KIAA1967 monoclonal antibody (M04), clone 4E6 Western Blot analysis of KIAA1967 expression in A-549. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details
Human Kaninchen Unkonjugiert IF, IP, WB Immunoprecipitation of KIAA1967 transfected lysate using anti-KIAA1967 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with KIAA1967 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of KIAA1967 expression in transfected 293T cell line by KIAA1967 MaxPab polyclonal antibody.<br><br>Lane 1: KIAA1967 transfected lysate(102.9 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cell lines, using CCAR2 antibody. Immunohistochemistry of paraffin-embedded rat kidney using CCAR2 antibody. 120 μL Anmelden zum Anzeigen 12 bis 14 Tage
$251.90
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of KIAA1967 expression in transfected 293T cell line by KIAA1967 MaxPab polyclonal antibody.<br><br>Lane 1: KIAA1967 transfected lysate(101.53 KDa).<br>Lane 2: Non-transfected lysate.<br> KIAA1967 MaxPab polyclonal antibody. Western Blot analysis of KIAA1967 expression in Jurkat. 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB <b>Western blot</b> analysis of KIAA1967 / DBC-1 in A549 whole cell lysate using KIAA1967 antibody . 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB   100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details

CCAR2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,
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Mouse (Murine) ,
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Rat (Rattus)
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Weitere Antikörper gegen CCAR2 Interaktionspartner

Human Cell Cycle and Apoptosis Regulator 2 (CCAR2) Interaktionspartner

  1. conclude, these findings demonstrated that DBC1 was essential in tumorigenesis and proliferation. Moreover, it was identified as a potential therapeutic target for HCC (zeige FAM126A Antikörper).

  2. Long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 (zeige TP53 Antikörper) acetylation.

  3. Data suggest that DBC1 has a dual function in regulating beta-catenin (zeige CTNNB1 Antikörper)-PROX1 (zeige PROX1 Antikörper) signaling axis: as a coactivator for both beta-catenin (zeige CTNNB1 Antikörper) and PROX1 (zeige PROX1 Antikörper).

  4. important role for CCAR2 in maintaining cell cycle progression and promoting squamous cell carcinoma (SCC (zeige CYP11A1 Antikörper)) tumorigenesis.

  5. Data show that the interaction between cell cycle and apoptosis regulator 2 (CCAR2) and heat shock protein 60 (Hsp60 (zeige HSPD1 Antikörper)) increases in the presence of rotenone.

  6. Results found transcriptional levels of DBC1,a negative regulator of HDAC3 (zeige HDAC3 Antikörper) significantly reduced in type 2 diabetes mellitus patients.

  7. DBC1 protein could be a prognostic marker of shorter recurrence-free survival in hepatocellular carcinoma patients after hepatectomy and human hepatocarcinogenesis was a multistep process accompanied by a stepwise increase in high DBC1 expression from low-grade dysplastic nodules, through high-grade dysplastic nodules, to hepatocellular carcinoma.

  8. Results suggest that DBC1 is integral to the maintenance of the circadian molecular clock.

  9. loss of DBC1 expression plays a role in tumorigenesis and tumor progression in gallbladder carcinoma.

  10. Proteosome-mediated degradation and poly-ubiquitination of AR were increased with the knock-down of DBC1.

CCAR2 Antigen-Profil

Protein Überblick

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.

Genbezeichner und Symbole assoziert mit CCAR2

  • cell cycle and apoptosis regulator 2 (CCAR2) Antikörper
  • DBC-1 Antikörper
  • DBC1 Antikörper
  • KIAA1967 Antikörper
  • NET35 Antikörper
  • p30 DBC Antikörper
  • p30DBC Antikörper

Bezeichner auf Proteinebene für CCAR2

DBIRD complex subunit KIAA1967 , deleted in breast cancer 1 , p30 DBC protein

GENE ID SPEZIES
57805 Homo sapiens
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