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CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Zusätzlich bieten wir Ihnen Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteine (35) und Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Kits (31) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal CEACAM1 Primary Antibody für EIA, FACS - ABIN114594
Hammarström: The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. in Seminars in cancer biology 1999
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Human Monoclonal CEACAM1 Primary Antibody für FACS - ABIN2689373
Kuroki, Arakawa, Matsuo, Oikawa, Misumi, Nakazato, Matsuoka: Molecular cloning of nonspecific cross-reacting antigens in human granulocytes. in The Journal of biological chemistry 1991
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Human Monoclonal CEACAM1 Primary Antibody für FACS - ABIN2689374
Siler, Eggensperger, Hand, Milenic, Miller, Houchens, Hinkle, Schlom: Therapeutic efficacy of a high-affinity anticarcinoembryonic antigen monoclonal antibody (COL-1). in Biotechnology therapeutics 1994
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Human Monoclonal CEACAM1 Primary Antibody für CyTOF, FACS - ABIN4900284
Rahmoun, Molès, Pedretti, Mathieu, Fremaux, Raison-Peyron, Lecron, Yssel, Pène: Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils. in The Journal of investigative dermatology 2009
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Human Monoclonal CEACAM1 Primary Antibody für IHC (p), WB - ABIN3043635
Li, Chen, Zeng, Li, Zhang, Lin, Zhang, Xie, He, Shu, Yang, Tang, Fu: Matrigel basement membrane matrix induces eccrine sweat gland cells to reconstitute sweat gland-like structures in nude mice. in Experimental cell research 2015
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Human Monoclonal CEACAM1 Primary Antibody für FACS - ABIN4897487
Gebauer, Wicklein, Tachezy, Grob, Steinemann, Manukjan, Göhring, Schlegelberger, Maar, Izbicki, Bockhorn, Schumacher: Establishment and Characterization of a Pair of Patient-derived Human Non-small Cell Lung Cancer Cell Lines from a Primary Tumor and Corresponding Lymph Node Metastasis. in Anticancer research 2016
we show here that Human Metapneumovirus (HMPV)-infected cells upregulates CEACAM1 to restrict HMPV infection
Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1, CEACAM3 (zeige CEACAM3 Antikörper), CEACAM5 (zeige CEACAM5 Antikörper) or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA (zeige S100A8 Antikörper) into host cells.
Here, the authors identify members of the carcinoembryonic antigen (zeige CEACAM5 Antikörper)-related cell adhesion molecule (zeige MCAM Antikörper) (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1, CEACAM3 (zeige CEACAM3 Antikörper), CEACAM5 (zeige CEACAM5 Antikörper) and CEACAM6.
Data show that SOX9 (zeige SOX9 Antikörper) regulates CEACAM1 primarily via Sp1 (zeige PSG1 Antikörper) and ETS1 (zeige ETS1 Antikörper).
short cytoplasmic domain isoforms at the primary lesion invasion front associated with recurrence and prognosis of patients with colorectal liver metastasis after curative hepatectomy; expression of CEACAM1-4S enhances the tumor-initiating property of colorectal cancer cells
Results report that CEACAM1 was uniquely expressed at high levels in both human neoplastic mast cells (mastocytosis) and medullary thyroid carcinoma cell (MTC (zeige MT1A Antikörper)) lines, and suggest that the dominantly interacting proteins SHP1 (zeige PTPN6 Antikörper) or SFK determine whether CEACAM1-L displays a positive or negative role in tumor cells. .
SASH1 (zeige SASH1 Antikörper) acts through NOTCH1 (zeige NOTCH1 Antikörper) and its inhibitor DLK1 (zeige DLK1 Antikörper) in a three-dimensional model of lumenogenesis involving CEACAM1.
CEACAM1 also inhibits viral spread in ex vivo human decidua organ culture.
In enterocytic C2BBe1 cells, Candida albicans caused a transient tyrosine phosphorylation of CEACAM1 and induced higher expression of membrane-bound CEACAM1 and soluble CEACAM6.
REVIEW: summarizes the vascular effects of CEACAM1 and focuses on its role in vascular morphogenesis and endothelial barrier regulation
A 30-day high fat feeding regimen demonstrated that white adipose tissue-derived fatty acids repressed hepatic CEACAM1-dependent regulation of insulin (zeige INS Antikörper) and lipid metabolism in 3-month-old male C57BL/6J mice.
CEACAM1 exacerbates hypoxic cardiomyocyte injury and post-infarction cardiac remodeling by enhancing cardiomyocyte mitochondrial dysfunction and endoplasmic reticulum stress-induced apoptosis.
The increase in total fat mass in Cc1 (zeige RB1CC1 Antikörper)(-/-) mice is mainly attributed to hyperphagia and reduced spontaneous physical activity. Although the contribution of the loss of CEACAM1 from anorexigenic proopiomelanocortin (zeige POMC Antikörper) neurons in the arcuate nucleus is unclear, leptin (zeige LEP Antikörper) resistance and elevated hypothalamic fatty-acid synthase (zeige FASN Antikörper) activity could underlie altered energy balance in these mice.
Ceacam1 is essential for normal integrin aIIbb3-mediated platelet function; the disruption of mouse Ceacam1 induced moderate integrin aIIbb3-mediated functional defects.
hepatic CEACAM1 expression at fasting is mediated by Pparalpha (zeige PPARA Antikörper)-dependent mechanisms.
Gram-positive bacteria promote the mRNA expression of CEACAM1 or CEACAM20 in the small intestine. Inflammatory cytokines or butyrate likely participates in such effects of commensal bacteria.
CEACAM1 is a crucial regulator of B-cell survival, influencing B-cell numbers and protective antiviral antibody responses
High-fat diet amplifies the permissive effect of Ceacam1 deletion on renal expression of all renin (zeige REN Antikörper)-angiotensin system components, PI3K phosphorylation, inflammation, and fibrosis.
Ceacam1L acts as a crucial factor in glioblastoma-initiating cell maintenance and tumorigenesis by activating c-Src (zeige SRC Antikörper)/STAT3 (zeige STAT3 Antikörper) signaling. Monomers of the cytoplasmic domain of Ceacam1L bound to c-Src (zeige SRC Antikörper) and STAT3 (zeige STAT3 Antikörper) and induced their phosphorylation.
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
, antigen CD66
, carcinoembryonic antigen-related cell adhesion molecule 1
, ATP-dependent taurocolate-carrier protein
, C-CAM 105
, CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin)
, bone gamma-carboxyglutamic acid (Gla) protein
, cell-CAM 105
, CEA-related cell adhesion molecule 1
, biliary glycoprotein 1
, biliary glycoprotein D
, carcinoembryonic antigen 1
, carcinoembryonic antigen 7
, hepatitis virus (MHV-4) susceptibility
, hepatitis virus receptor
, murine hepatitis virus receptor
, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
, carcinoembryonic antigen-related cell adhesion molecule 6