Calpastatin (CAST) ELISA Kits

The protein encoded by CAST is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. Zusätzlich bieten wir Ihnen Calpastatin Antikörper (86) und Calpastatin Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CAST 831 P20810
CAST 12380  
CAST 25403 P27321
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Top Calpastatin ELISA Kits auf

Showing 6 out of 18 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.39 ng/mL 1.56-100 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Rind (Kuh) 7.81 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Maus 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Schwein 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
Maus 18.75 pg/mL 31.25 pg/mL - 2000 pg/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für Calpastatin Interaktionspartner

Human Calpastatin (CAST) Interaktionspartner

  1. Kaposi sarcoma-associated herpesvirus reduces CAST (calpastatin) and consequently decreases ATG5 (zeige ATG5 ELISA Kits) expression in both THP-1 (zeige GLI2 ELISA Kits) monocytoid cells and primary monocytes.

  2. calpains and calpastatin in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (zeige TAGLN ELISA Kits)-5HTT (zeige SLC6A4 ELISA Kits)(+) strain) PH, were investigated.

  3. Loss of CAST in angiogenic ECs facilitates mu (zeige JAK3 ELISA Kits)-calp (zeige STAT1 ELISA Kits)ain-induced SOCS3 degradati (zeige SOCS3 ELISA Kits)on, which amplifies p (zeige VEGFC ELISA Kits)athological angiogenesis through interleukin-6/STAT3/VEGF-C axis.

  4. We describe PLACK syndrome, as a clinical entity of defective epidermal adhesion, caused by loss-of-function mutations in calpastatin.

  5. Calpastatin binds with Cav1.2 (zeige CACNA1C ELISA Kits) amino acid motifs in a calcium dependent manner.

  6. Calpastatin gene (CAST) is not associated with late onset sporadic Parkinson's disease in the Han Chinese population.

  7. HER2 (zeige ERBB2 ELISA Kits) inhibited calpain-1 (zeige CAPN1 ELISA Kits) activity through upregulating calpastatin, an endogenous calpain inhibitor.

  8. The results suggest that calpain-2 (zeige CAPN2 ELISA Kits) and calpastatin expression is important in pancreatic cancers, influencing disease progression

  9. Neuronal overexpression of calpastatin modulates amyloid precursor protein (zeige APP ELISA Kits) processing in brains of transgenic beta-amyloid depositing mice.

  10. Calpastatin overexpression reduces calpain-mediated proteolysis and behavioral impairment after traumatic brain injury.

Mouse (Murine) Calpastatin (CAST) Interaktionspartner

  1. calpains and calpastatin in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (zeige TAGLN ELISA Kits)-5HTT (zeige SLC6A4 ELISA Kits)(+) strain) PH, were investigated.

  2. Defective scar formation after myocardial infarction in calpastatin transgenic mice was associated with blunted CD4 (zeige CD4 ELISA Kits)(+) T-cell and M2-macrophage recruitment.

  3. Over-expression of Cast inhibits calpain activation and attenuates post-infarction myocardial remodeling.

  4. EC-specific transgenic CAST downregulated JAK (zeige JAK3 ELISA Kits)/STAT (zeige STAT1 ELISA Kits) signals, upregulated SOCS3 (zeige SOCS3 ELISA Kits), and depleted VEGF-C (zeige VEGFC ELISA Kits), counteracting unstable pathological neovessels and disease progression in tumors and oxygen-induced retinopathy lesions in mice.

  5. Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-synuclein processing, aggregation and synaptic impairment in transgenic mice.

  6. We observed that ischemia induction results in increased expression of CaN, Calp and Calpn.

  7. Over-expression of calpastatin enhances doxorubicin-induced cardiac injuries through calpain inhibition.

  8. The calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma.

  9. Data show that genetic deficiency of calpastatin (CS) augmented Abeta (zeige APP ELISA Kits) amyloidosis, tau phosphorylation, microgliosis, and somatodendritic dystrophy, and increased mortality in amyloid precursor protein (APP (zeige APP ELISA Kits)) transgenic mice.

  10. PIN1 apparently restrains the ability of calpastatin to inhibit calpain, maintaining calpain activity in endothelial cells.

Cow (Bovine) Calpastatin (CAST) Interaktionspartner

  1. The calpastatin gene (CAST), which is located on bovine chromosome 7 (BTAU7), is considered a strong functional candidate for meat tenderness in livestock species.

  2. The suppression of calpastatin resulted in the increased expression of mu-calpain (zeige CAPNL1 ELISA Kits), caspases, and HSPs which in turn regulate apoptotic cell death.

  3. This work is supportive of the importance of CAPN1 (zeige CAPNL1 ELISA Kits) and CAST for mean tenderness in beef.

  4. bovine CAPN-CAST interaction were well reflected in the geometry between the pharmacophore features and its shape constraints identified using our modeled bovine CAPN1 (zeige CAPNL1 ELISA Kits)/CAST4 complex structures

  5. CAST binds and inhibits CAPN via its CAPN-inhibitor domains(CAST1-4) .CAST4 docks near the flexible active site of CAPN1 (zeige CAPNL1 ELISA Kits), conformational changes at the interaction site after binding could be directly related to CAST4 inhibitory activity.

  6. This work confirms the importance of CAPN1 (zeige CAPNL1 ELISA Kits) and CAST for tenderness in beef, provides a new effect of CAST on beef tenderness, and questions the utility of GHR (zeige GHR ELISA Kits) as a selection marker for beef quality.

  7. The association of single nucleotide polymorphisms in calpastatin with muscle tenderness was studied.

  8. Association of polymorphisms in calpain 1 (zeige CAPN1 ELISA Kits), (mu/I) large subunit, calpastatin, and cathepsin D (zeige CTSD ELISA Kits) genes with meat quality traits in double-muscled Piemontese cattle.

  9. The CAST28 genotypes showing allele frequencies of C (0.429) and T (0.571) were significantly associated with calpastatin activity and Warner-Bratzler Shear Force in beef.

  10. The association of polymorphisms in calpastatin and mu-calpain (zeige CAPNL1 ELISA Kits) genes with meat tenderness in 3 French beef breeds is reported.

Pig (Porcine) Calpastatin (CAST) Interaktionspartner

  1. CT1 (zeige SLC6A8 ELISA Kits) decreases cell death through a mechanism related to Stat3 (zeige STAT3 ELISA Kits) and Akt (zeige AKT1 ELISA Kits) phosphorylation and activation of calpastatin in D-galactosamine-treated hepatocytes.

  2. CAST gene affected post-mortem activation time of calpain and drip loss.

  3. The quality of meat influenced by RYR1 (zeige RYR1 ELISA Kits) genotype may be modified by the simultaneous influence of genotype as regards the CAST locus

  4. The effect of the beta-adrenergic agonist clenbuterol and porcine ST (pST (zeige SULT1A1 ELISA Kits)) treatment on calpastatin promoter usage in vivo and in vitro are reported.

  5. The Decreased expression of calpastatin mRNA during development is highly correlated with muscle protein accumulation in neonatal Sus scrofa.

Calpastatin (CAST) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit Calpastatin (CAST) ELISA Kits

  • calpastatin (CAST) Antikörper
  • calpastatin (Cast) Antikörper
  • calpastatin S homeolog (cast.S) Antikörper
  • calpastatin (cast) Antikörper
  • calpastatin (VDBG_09182) Antikörper
  • Calpastatin (ical) Antikörper
  • BS-17 Antikörper
  • calp3 Antikörper
  • cast Antikörper
  • DKFZp469E0716 Antikörper
  • sb:cb966 Antikörper
  • zgc:194249 Antikörper

Bezeichner auf Proteinebene für Calpastatin (CAST) ELISA Kits

calpain inhibitor , sperm BS-17 component , calpastatin type III , calpastatin isoform III , calpastatin type I , calpastatin type II , calpastatin , Calpastatin , calpastatin-like

831 Homo sapiens
12380 Mus musculus
25403 Rattus norvegicus
281039 Bos taurus
397135 Sus scrofa
398115 Xenopus laevis
427121 Gallus gallus
443364 Ovis aries
462348 Pan troglodytes
479148 Canis lupus familiaris
563084 Danio rerio
703623 Macaca mulatta
9528399 Verticillium alfalfae VaMs.102
100009098 Oryctolagus cuniculus
100073225 Equus caballus
100136674 Oncorhynchus mykiss
100145371 Xenopus (Silurana) tropicalis
100174647 Pongo abelii
100380407 Salmo salar
100391897 Callithrix jacchus
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