Calpain 2 Proteine (CAPN2)

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (By similarity).. Zusätzlich bieten wir Ihnen Calpain 2 Antikörper (59) und Calpain 2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus CAPN2 CAPN2 12334 O08529
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Top Calpain 2 Proteine auf

Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 4 Days
Hefe Plasmodium vivax His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Trypanosoma brucei His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Rind (Kuh) Unkonjugiert   10 μg Anmelden zum Anzeigen 6 Days

CAPN2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Am meisten referenzierte Calpain 2 Proteine

  1. Human Calpain 2 Protein expressed in HEK-293 Cells - ABIN2713061 : Briz, Hsu, Li, Lee, Bi, Baudry: Calpain-2-mediated PTEN degradation contributes to BDNF-induced stimulation of dendritic protein synthesis. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)
    Show all 3 Pubmed References

Weitere Proteine zu Calpain 2 (CAPN2) Interaktionspartnern

Mouse (Murine) Calpain 2 (CAPN2) Interaktionspartner

  1. Results indicate that calpain-1 (zeige CAPN1 Proteine) and calpain-2 are differentially activated in hippocampus following seizure activity, with calpain-1 (zeige CAPN1 Proteine) activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 is widely activated in pyramidal neurons of CA1 (zeige CA1 Proteine) and CA3 (zeige CA3 Proteine), and triggers neurodegenerative cascades.

  2. these findings identify ASAP2 (zeige ASAP2 Proteine) as a new target of Selk (zeige HSP Proteine)-dependent palmitoylation and reveal a new mechanism regulating the efficiency of FcgammaR-mediated phagocytosis.

  3. ENaC (zeige SCNN1A Proteine) activity is regulated by calpain-2 proteolysis of MARCKS (zeige MARCKS Proteine).

  4. calpains and calpastatin (zeige CAST Proteine) in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (zeige TAGLN Proteine)-5HTT (zeige SLC6A4 Proteine)(+) strain) PH, were investigated.

  5. Leukocyte calpain-1 (zeige CAPN1 Proteine)/calpain-2 deficiency reduces angiotensin II-induced inflammation and atherosclerosis but not abdominal Aortic aneurysms in mice.

  6. These results suggest that TRPV1 (zeige TRPV1 Proteine)/Ca(2 (zeige CA2 Proteine)+)/calpain 2-dependent signaling plays a dominant role in capsaicin-induced ablation of nociceptive terminals and further our understanding of the molecular mechanisms underlying the effects of capsaicin on nociceptors.

  7. Calpain-2 modulates pulmonary vascular remodeling in pulmonary arterial hypertension.

  8. LOX-1 (zeige OLR1 Proteine) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (zeige CAPN1 Proteine) and -2.

  9. Dicer is predominantly a Capn2 substrate. Dicer levels were altered in platelets from diabetic mice due to the cleavage of the enzyme by calpain, resulting in loss of function.

  10. Data suggest that vitamin D3 up-regulates skeletal muscle fat deposition, up-regulates muscle m-calpain/Capn2 and u-calpain/Capn1 expression, and down-regulates muscle calpastatin expression.

Calpain 2 (CAPN2) Protein Überblick

Protein Überblick

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (By similarity).

Genbezeichner und Symbole assoziert mit Calpain 2 Proteine (CAPN2)

  • calpain 2 (Capn2)
  • calpain 2, gene2 (capn2.2)
  • calpain 2 (CAPN2)
  • AI326419 Protein
  • Capa-2 Protein
  • Capa2 Protein
  • CAPN2 Protein
  • m-calpain Protein
  • m-calpin Protein

Bezeichner auf Proteinebene für Calpain 2 Proteine (CAPN2)

80 kDa M-calpain subunit , CALP80 , CANP 2 , calcium-activated neutral proteinase 2 , calpain M-type , calpain-2 catalytic subunit , calpain-2 large subunit , cysteine proteinase , m-calpain 80 kDa large subunit , m-calpain large subunit , millimolar-calpain , calpain 2

12334 Mus musculus
448035 Xenopus (Silurana) tropicalis
100127211 Ovis aries
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