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Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (By similarity).. Zusätzlich bieten wir Ihnen Calpain 2 Antikörper (59) und Calpain 2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Calpain 2 Protein expressed in HEK-293 Cells - ABIN2713061
Briz, Hsu, Li, Lee, Bi, Baudry: Calpain-2-mediated PTEN degradation contributes to BDNF-induced stimulation of dendritic protein synthesis. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Show all 3 Pubmed References
Results indicate that calpain-1 (zeige CAPN1 Proteine) and calpain-2 are differentially activated in hippocampus following seizure activity, with calpain-1 (zeige CAPN1 Proteine) activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 is widely activated in pyramidal neurons of CA1 (zeige CA1 Proteine) and CA3 (zeige CA3 Proteine), and triggers neurodegenerative cascades.
these findings identify ASAP2 (zeige ASAP2 Proteine) as a new target of Selk (zeige HSP Proteine)-dependent palmitoylation and reveal a new mechanism regulating the efficiency of FcgammaR-mediated phagocytosis.
ENaC (zeige SCNN1A Proteine) activity is regulated by calpain-2 proteolysis of MARCKS (zeige MARCKS Proteine).
calpains and calpastatin (zeige CAST Proteine) in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (zeige TAGLN Proteine)-5HTT (zeige SLC6A4 Proteine)(+) strain) PH, were investigated.
Leukocyte calpain-1 (zeige CAPN1 Proteine)/calpain-2 deficiency reduces angiotensin II-induced inflammation and atherosclerosis but not abdominal Aortic aneurysms in mice.
These results suggest that TRPV1 (zeige TRPV1 Proteine)/Ca(2 (zeige CA2 Proteine)+)/calpain 2-dependent signaling plays a dominant role in capsaicin-induced ablation of nociceptive terminals and further our understanding of the molecular mechanisms underlying the effects of capsaicin on nociceptors.
Calpain-2 modulates pulmonary vascular remodeling in pulmonary arterial hypertension.
LOX-1 (zeige OLR1 Proteine) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (zeige CAPN1 Proteine) and -2.
Dicer is predominantly a Capn2 substrate. Dicer levels were altered in platelets from diabetic mice due to the cleavage of the enzyme by calpain, resulting in loss of function.
Data suggest that vitamin D3 up-regulates skeletal muscle fat deposition, up-regulates muscle m-calpain/Capn2 and u-calpain/Capn1 expression, and down-regulates muscle calpastatin expression.
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (By similarity).
80 kDa M-calpain subunit
, CANP 2
, calcium-activated neutral proteinase 2
, calpain M-type
, calpain-2 catalytic subunit
, calpain-2 large subunit
, cysteine proteinase
, m-calpain 80 kDa large subunit
, m-calpain large subunit
, calpain 2