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The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases.
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calpain 12 plays an essential role during epidermal ontogenesis and normal hair follicle cycling.
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family.
, calcium-activated neutral proteinase 12