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CACNA1I encodes the pore-forming alpha subunit of a voltage gated calcium channel. Zusätzlich bieten wir Ihnen CACNA1I Antikörper (19) und viele weitere Produktgruppen zu diesem Protein an.
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Extracellular pressure increases [Ca(2 (zeige CA2 Proteine)+)]i via Cav3.3, driving a PKC-beta (zeige PRKCB Proteine)- IKK (zeige CHUK Proteine)- IkB (zeige NFKBIB Proteine)-NF-kB pathway that stimulates cancer cell proliferation
using Ca(V)3.3(-/-) mice we found that Ca(V)3.3 channels trigger synaptic plasticity in reticular thalamic neurons
data identify a central role for Ca(V)3.3 channels in the rhythmogenic properties of the sleep-spindle generator and provide a molecular target to elucidate the roles of sleep spindles for brain function and development.
human Cav3.1, Cav3.2, and Cav3.3 T-type channels specifically associate with CaM at helix 2 of the gating brake in the I-II linker of the channels.
significant association exists between the CACNA1I gene and schizophrenia in the Uighur Chinese population
CACNA1I variant is associated with differential antiepileptic drug response in childhood absence epilepsy.
CaV3.1 (zeige CACNA1G Proteine), CaV3.2 (zeige CACNA1H Proteine) and CaV3.3 channels, are best recognized for their negative voltage of activation and inactivation thresholds that allow them to operate near the resting membrane potential of neurons.
Ethanol primarily affects the CaV3.2 isoform of T-type Ca(2)+ channels, acting through protein kinase C.
Specific contribution of human T-type calcium channel isotypes (alpha(1G (zeige CACNA1G Proteine)), alpha(1H) and alpha(1I)) to neuronal excitability.
intracellular regions after repeats I and IV play a role in gating interdependently, suggesting a direct interaction, and splice variation of Cav3.3 channels provides a mechanism for fine-tuning latency and duration of low-threshold spikes.
CatSper1 (zeige CATSPER1 Proteine) and CatSper2 (zeige CATSPER2 Proteine) can associate with and modulate the function of the Ca(v)3.3 channel, which might be important in the regulation of sperm function.
two distinct regions of the Cav3.3 channel are necessary and sufficient for complete M1 receptor-mediated channel inhibition
This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants.
alpha1I T-type calcium channel subunit
, calcium channel, voltage-dependent, T type, alpha 1I subunit
, voltage-dependent T-type calcium channel alpha-1I subunit
, voltage-dependent T-type calcium channel subunit alpha-1I-like
, low voltage-activated T-type calcium channel alpha-1 subunit (CACNA1I)
, low-voltage-activated calcium channel alpha13.3
, calcium channel, voltage-dependent, alpha 1I subunit
, voltage-dependent T-type calcium channel subunit alpha-1I
, voltage-gated calcium channel subunit alpha Cav3.3
, hypothetical gene supported by NM_020084
, voltage-dependent calcium channel