Calcineurin (CAN) ELISA Kits

Calcium-dependent, calmodulin-stimulated protein phosphatase. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CAN 5530 Q08209
CAN 19055 P63328
CAN 24674 P63329
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Top Calcineurin ELISA Kits auf

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Human 0.055 ng/mL 0.156 ng/mL - 10 ng/mL 96 Tests 15 bis 17 Tage
Ratte 0.064 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Maus 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Ratte < 0.064 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 bis 18 Tage

Am meisten referenzierte Calcineurin ELISA Kits

  1. Mouse (Murine) CAN ELISA Kit für Sandwich ELISA - ABIN424751 : Krenzien, Quante, Heinbokel, Seyda, Minami, Uehara, Biefer, Schuitenmaker, Gabardi, Splith, Schmelzle, Petrides, Azuma, Pratschke, Li, ElKhal, Tullius: Age-Dependent Metabolic and Immunosuppressive Effects of Tacrolimus. in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2016 (PubMed)

Weitere ELISA Kits für Calcineurin Interaktionspartner

Human Calcineurin (CAN) Interaktionspartner

  1. Gln442Ter mutation causes epilepsy, constitutive enzyme activation and downregulation of protein expression.

  2. Loss-of-function and gain-of-function mutations in PPP3CA cause two distinct disorders.

  3. The underlying mechanism forAT1-autoantibody induced podocyte damage might involve activation of the TRPC6 -calcium/calcineurin pathway.

  4. A short-linear interaction motif between residues 337-343 of AKAP79 is the sole PP2B-anchoring determinant sustaining these diverse topologies.

  5. Mutation in PPP3CA gene is associated with Severe Neurodevelopmental Disease with Seizures.

  6. identify a distinct C-terminal autoinhibitory four-residue sequence in CNAbeta1, (462)LAVP(465), which competitively inhibits substrate dephosphorylation. In vitro and cell-based assays revealed that the CNAbeta1-containing holoenzyme, CNbeta1, is autoinhibited at a single site by either of two inhibitory regions, CBD and LAVP, which block substrate access to the substrate-binding groove.

  7. Studies indicate the importance of the AKAP79/PP2B/protein kinase A complex's role in synaptic long-term depression in the CA1 region of the hippocampus.

  8. Ca(2+)/calcineurin (CaN)/nuclear factor of activated T-cells (NFAT) c4 axis is required for neuritin-induced Kv4.2 transcriptional expression and potentiation of IA densities in cerebellum granule neurons.

  9. CN-A and nephrin were clearly reduced in the kidneys of a 10-year-old boy who had relapsing steroid-resistant nephrotic syndrome.

  10. that KIF1Bbeta affects mitochondrial dynamics through calcineurin-dependent dephosphorylation of Dynamin-related protein 1 (DRP1), causing mitochondrial fission and apoptosis

  11. for Aspergillus fumigatus, activation of macrophage calcineurin-NFAT occurs via a phagosomal TLR9-dependent and Bruton's tyrosine kinase-dependent signalling pathway that is independent of MyD88

  12. Data indicate that both nuclear factors of activated T cells (NFATs) motifs partially compete for binding but do not fully displace each other on the calcineurin (Cn) epitope.

  13. Lysosomal calcium signaling regulates autophagy through calcineurin and TFEB.

  14. Human herpesvirus 6B U54 binds the calcineurin (CaN) phosphatase enzyme, causing improper dephosphorylation and nuclear translocation of NFAT (nuclear factor of activated T cells) proteins, resulting in suboptimal IL-2 gene transcription.

  15. KSR2 deficiency affects stromal interaction molecule 1 (STIM1)/ORAI1 puncta formation, which is correlated with cytoskeleton disorganization.

  16. These findings therefore provide initial support for the novel mechanistic hypothesis that oxidation-induced global and/or local conformational changes within calcineurin

  17. PKCepsilon may negatively regulate adverse myocardial remodeling by cooperating with calcineurin to downregulate fibrosis and induce transcription of cardioprotective wound healing genes, including COX-2

  18. Mutations on the hydrophobic face of Calcineurin distal helix disrupt the structure gained upon CaM binding.

  19. Bile-induced NF-kappaB activation and acinar cell injury are mediated by calcineurin.

  20. Dephosphorylation of Aly1 by calcineurin serves as a regulatory switch to promote Aly1-mediated trafficking to the vacuole.

Fruit Fly (Drosophila melanogaster) Calcineurin (CAN) Interaktionspartner

  1. results suggest a key role for calcineurin in cardiac remodeling during long-term hypoxia with implications for diseases of chronic hypoxia, and it likely contributes to mechanisms underlying these disease states.

  2. upregulation of Nebula/DSCR1 is neuroprotective in the presence of APP upregulation and provides evidence for calcineurin inhibition as a novel target for therapeutic intervention in preventing axonal transport impairments associated with AD.

  3. results indicate a role for Cn and calcium-dependent signal transduction in sleep and memory regulation.

  4. calcineurin, upon activation by Ca(2+)-calmodulin, cooperates with other factors to negatively regulate Egf receptor signaling at the level of sprouty and the GTPase-activating protein Gap1

Mouse (Murine) Calcineurin (CAN) Interaktionspartner

  1. IFNG utilizes the PPP3-TFEB signaling axis for inducing autophagy and regulating mycobacterial growth.

  2. within interneurons, Calcineurin, a calcium-dependent protein phosphatase, plays a critical role in sequentially linking activity to maturation (E15-P5) and survival (P5-P20).

  3. calcineurin in astrocytes may be activated in response to neuronal activity.

  4. calcineurin is a key regulator of Wnt5a-induced AQP2 activation without affecting intracellular cAMP level and PKA activity.

  5. Redirected splicing of calcineurin A to the fetal isoforms in adult muscle and in differentiated C2C12 slows the timing of muscle relaxation, promotes nuclear localization of calcineurin target Nfatc3, and/or affects expression of Nfatc transcription targets.

  6. these results demonstrate that increased susceptibility to Aspergillus fumigatus is dependent on calcineurin signaling in myeloid cells

  7. the CaN-Nfat pathway regulates development and function of IFN-gamma-producing gammadelta T cells.

  8. the expression of the full-length 60-kDa calcineurin protein is down-regulated due to over-activated calpain that cleaves calcineurin to form a 45-kDa fragment.

  9. Ca(2+)/calcineurin (CaN)/nuclear factor of activated T-cells (NFAT) c4 axis is required for neuritin-induced Kv4.2 transcriptional expression and potentiation of IA densities in cerebellum granule neurons.

  10. AKAP150-calcineurin signaling dyad is essential for the activation of the phosphatase and the subsequent down-regulation of Kv channel currents following myocardial infarction.

  11. Calcineurin inhibitor tacrolimus ameliorated proteinuria in nephrotic model by inhibiting the redistribution of CN-A and nephrin at the slit diaphragm.

  12. global deficiency of catalytic subunit Ppp3cb, and tissue-specific ablation of regulatory subunit Ppp3r1 from skeletal muscle, but not adipose tissue or liver, led to protection from high-fat-diet-induced obesity

  13. Overexpression of the phosphatase calcineurin A prevents the development of a capillary/myocyte mismatch despite progressive myocardial hypertrophy.

  14. Catalytic subunits of the phosphatase calcineurin interact with NF-kappaB-inducing kinase (NIK) and attenuate NIK-dependent gene expression

  15. Data indicate that calcineurin (CnAalpha-/- or CnAbeta-/-) is required for pathological but not compensatory renal hypertrophy.

  16. We also confirmed that overexpression of RCAN1-1L could inhibit the transcriptional activation of an NFAT-dependent promoter in response to PMA and ionomycin by inhibiting Calcineurin activity in HEK293T cells

  17. A calcineurin- and NFAT-dependent pathway is involved in alpha-synuclein-induced degeneration of midbrain dopaminergic neurons in a Parkinson's disease mouse model.

  18. Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion.

  19. KSR2 deficiency affects stromal interaction molecule 1 (STIM1)/ORAI1 puncta formation, which is correlated with cytoskeleton disorganization.

  20. Data indicate that reduction in connexin43 (Cx43) and sodium channel NaV1.5 expression coincided with overexpression of transgene calcineurin A (CnA) and hypertrophy development and preceded significant presence of fibrosis.

Pig (Porcine) Calcineurin (CAN) Interaktionspartner

  1. molecular cloning and characterization of expression in skeletal muscle

Calcineurin (CAN) Antigen-Profil

Beschreibung des Gens

catalytic subunit of Calcineurin (CaN), ubiquitously expressed Ca2+/CaM-dependent protein phosphatase\; mediates activities of transcription factors and ion channels\; involved in regulation of T-cell activation

Genbezeichner und Symbole assoziert mit Calcineurin (CAN) ELISA Kits

  • protein phosphatase 3 catalytic subunit alpha (PPP3CA) Antikörper
  • Calcineurin A1 (CanA1) Antikörper
  • protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca) Antikörper
  • protein phosphatase 3 catalytic subunit alpha (Ppp3ca) Antikörper
  • 2900074D19Rik Antikörper
  • AI841391 Antikörper
  • AW413465 Antikörper
  • Caln Antikörper
  • Calna Antikörper
  • Calna1 Antikörper
  • Can Antikörper
  • canA Antikörper
  • Cana1 Antikörper
  • CAN A1/PP2B Antikörper
  • CCN1 Antikörper
  • CG1455 Antikörper
  • CN Antikörper
  • CnA Antikörper
  • CNA1 Antikörper
  • CnnA21EF Antikörper
  • D14 Antikörper
  • DmCanA1-100B Antikörper
  • Dmel\\CG1455 Antikörper
  • pMY4 Antikörper
  • PP2B Antikörper
  • PP2B 21EF Antikörper
  • PpD14 Antikörper
  • PPP2B Antikörper

Bezeichner auf Proteinebene für Calcineurin (CAN) ELISA Kits

CAM-PRP catalytic subunit , calcineurin A alpha , calmodulin-dependent calcineurin A subunit alpha isoform , protein phosphatase 2B, catalytic subunit, alpha isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform , serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform , CG1455-PA , CG1455-PB , CG1455-PD , CanA1-PA , CanA1-PB , CanA1-PD , calcineurin , calcineurin A , calcineurin A1 , protein phosphatase D14 , protein phosphatase from PCR fragment D14 , PP2B alpha 1 , PP2BA alpha , Calcineurin subunit A alpha , protein phosphatase 3, catalytic subunit, alpha isoform , protein phosphatase-2Ba , calcineurin catalytic subunit delta isoform

5530 Homo sapiens
43670 Drosophila melanogaster
19055 Mus musculus
24674 Rattus norvegicus
397241 Sus scrofa
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