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Cadherins are calcium dependent cell adhesion proteins.
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Our study supports the concept that the CDHR3 variant is an important susceptibility factor for severe adult asthma in individuals who develop the disease in early life.
CDHR3 is a susceptibility locus for early childhood Asthma with severe exacerbations.
the asthma susceptibility gene product CDHR3 mediates RV-C entry into host cells, and suggest that rs6967330 mutation could be a risk factor for RV-C wheezing illnesses.
the role of CDHR3 variants in the development of asthma with severe exacerbations based on genome-wide association study in Denmark
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells\; cadherins may thus contribute to the sorting of heterogeneous cell types.
cadherin-like protein 28