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CDHR2 is a member of the protocadherin family, which represents a subset of the larger cadherin superfamily.
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Human Polyclonal CDHR2 Primary Antibody für ELISA, WB - ABIN565780
Ose, Oharaa, Nagase: Galectin-1 and Galectin-3 Mediate Protocadherin-24-Dependent Membrane Localization of ?-catenin in Colon Cancer Cell Line HCT116. in Current chemical genomics 2012
Human Polyclonal CDHR2 Primary Antibody für IHC, IHC (p) - ABIN4344085
McConnell, Benesh, Mao, Tabb, Tyska: Proteomic analysis of the enterocyte brush border. in American journal of physiology. Gastrointestinal and liver physiology 2011
Study found that brush border assembly is driven by the formation of Ca(2 (zeige CA2 Antikörper)+)-dependent adhesion links between adjacent microvilli. Intermicrovillar links are composed of protocadherin-24 and mucin-like protocadherin (zeige CDHR5 Antikörper), which target to microvillar tips and interact to form a trans-heterophilic complex.
suppression of beta-catenin (zeige CTNNB1 Antikörper) signaling by PCDH24 leads to contact inhibition
This gene is a member of the protocadherin family, which represents a subset of the larger cadherin superfamily. The members of the protocadherin family encode non-classical cadherins that function as calcium-dependent cell-cell adhesion molecules. This protocadherin represents a new candidate for tumor suppression. Alternatively spliced transcript variants that encode the same protein have been identified.