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CDHR2 is a member of the protocadherin family, which represents a subset of the larger cadherin superfamily. Zusätzlich bieten wir Ihnen CDHR2 Proteine (8) und und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal CDHR2 Primary Antibody für IHC, IHC (p) - ABIN4344085
McConnell, Benesh, Mao, Tabb, Tyska: Proteomic analysis of the enterocyte brush border. in American journal of physiology. Gastrointestinal and liver physiology 2011
Human Polyclonal CDHR2 Primary Antibody für ELISA, WB - ABIN565780
Ose, Oharaa, Nagase: Galectin-1 and Galectin-3 Mediate Protocadherin-24-Dependent Membrane Localization of ?-catenin in Colon Cancer Cell Line HCT116. in Current chemical genomics 2012
Study found that brush border assembly is driven by the formation of Ca(2+)-dependent adhesion links between adjacent microvilli. Intermicrovillar links are composed of protocadherin-24 and mucin-like protocadherin, which target to microvillar tips and interact to form a trans-heterophilic complex.
CDHR24 is directly involved in cell and tissue morphogenesis
suppression of beta-catenin signaling by PCDH24 leads to contact inhibition
This gene is a member of the protocadherin family, which represents a subset of the larger cadherin superfamily. The members of the protocadherin family encode non-classical cadherins that function as calcium-dependent cell-cell adhesion molecules. This protocadherin represents a new candidate for tumor suppression. Alternatively spliced transcript variants that encode the same protein have been identified.