CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 Proteine (CTDSP1)

CTDSP1 encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. Zusätzlich bieten wir Ihnen CTDSP1 Antikörper (109) und CTDSP1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte CTDSP1 CTDSP1 363249  
CTDSP1 58190 Q9GZU7
CTDSP1 227292 P58466
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Top CTDSP1 Proteine auf antikoerper-online.de

Showing 5 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$492.31
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CTDSP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Weitere Proteine zu CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) Interaktionspartnern

Human CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) Interaktionspartner

  1. Our results provide a novel mechanistic insight into the activation of Myc by 27-HC via transcriptional repression of PP2A, SCP1 and FBW7 to increase Myc protein stability in breast cancer cells.

  2. SCP1 is the phosphatase that counterregulates the MAPK-mediated phosphorylation of Ser(68)-Twist1.

  3. SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Serine-62.

  4. hSCP1 may be an beta-O-linked N-acetylglucosamine modified protein in vivo.

  5. CTDSP1 activity stabilizes REST in stem cells and ERK-dependent phosphorylation combined with Pin1 activity promotes REST degradation in neural progenitors.

  6. SCP1 phosphatase substrate specificity: CdcA3 could be an enzymatic substrate for SCP1.

  7. Captured the phosphoryl-aspartate intermediate in the crystal structure of a Scp1D206A mutant soaked with para-nitrophenyl phosphate (pNPP), providing strong evidence for the proposed mechanism.

  8. Polymorphisms vary significantly between races; Not associated with TB susceptibility in Caucasians.

  9. SCP1 may play a role in the regulation of gene expression, possibly by controlling the transition from initiation/capping to processive transcript elongation

  10. results show that REST/NRSF recruits SCPs to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells

  11. SCP1 acts as a phosphatase for regulatory phosphorylations in the linker region of Smad1 and Smad2.

Mouse (Murine) CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) Interaktionspartner

  1. Consistently, the authors observed increased AKT phosphorylation and angiogenesis followed by enhanced tumorigenesis in Ctdsp1 (which encodes SCP1) gene - knockout mice. Importantly, they discovered that the membrane localization of SCP1 is crucial for impeding angiogenesis and tumor growth, and this localization depends on palmitoylation of a conserved cysteine motif within its NH2 terminus.

  2. Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas PKCalpha-phosphorylated BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP.

  3. Findings suggest that SCP1 may inhibit the osteoblastic differentiation induced by the BMP-Smad axis via Runx2 by suppressing downstream effector(s).

  4. Expression and purification of the active variant of recombinant murine Golli-interacting protein (GIP) and its characterization

CTDSP1 Protein Überblick

Protein Überblick

This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit CTDSP1

  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (CTDSP1)
  • CTD small phosphatase 1 (CTDSP1)
  • CTD small phosphatase 1 (Ctdsp1)
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (ctdsp1)
  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (HCAG_04820)
  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTRG_06220)
  • CTD small phosphatase 1 (ctdsp1)
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (Ctdsp1)
  • CTDSP1 Protein
  • fj83f12 Protein
  • GIP Protein
  • im:7141428 Protein
  • Nif3 Protein
  • NLI-IF Protein
  • NLIIF Protein
  • SCP1 Protein
  • wu:fj83f12 Protein
  • zgc:113169 Protein

Bezeichner auf Proteinebene für CTDSP1

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 , CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 , NLI-interacting factor 3 , nuclear LIM interactor-interacting factor 3 , small C-terminal domain phosphatase 1 , golli-interacting protein , small CTD phosphatase 1

GENE ID SPEZIES
608466 Canis lupus familiaris
516199 Bos taurus
459943 Pan troglodytes
363249 Rattus norvegicus
58190 Homo sapiens
553744 Danio rerio
5447218 Ajellomyces capsulatus NAm1
8301559 Candida tropicalis MYA-3404
100350904 Oryctolagus cuniculus
100380164 Xenopus (Silurana) tropicalis
227292 Mus musculus
100726065 Cavia porcellus
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