anti-CREB Regulated Transcription Coactivator 1 (CRTC1) Antikörper

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Zusätzlich bieten wir Ihnen CRTC1 Proteine (8) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CRTC1 23373 Q6UUV9
CRTC1 382056 Q68ED7
CRTC1 684527 Q157S1
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Top anti-CRTC1 Antikörper auf antikoerper-online.de

Showing 10 out of 87 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB L1 rat brain, L2 human colon carcinoma lysates probed (ABIN746558) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band and observed band size: 73kDa HeLa cells probed with Rabbit Anti-Torc1 (Ser151) Polyclonal Antibody . 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$328.90
Details
Rind (Kuh) Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$619.30
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: TORC1 Antibody [ABIN250744] - Section of human breast carcinoma. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of Torc1/Crtc1 (Phospho-Ser151) using PMA treated Jurkat whole cell lysates 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$450.00
Details
Human Maus Unkonjugiert ELISA, FACS, ICC, WB Figure 1: Western blot analysis using CRTC1 mouse mAb against CRTC1(AA: 1-353)-hIgGFc transfected HEK293 cell lysate. Dilution: 1/500 - 1/2000 Figure 2: Immunofluorescence analysis of U251 (left) and NTERA2 (right) cells using CRTC1 mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye. Dilution: 1/200 - 1/1000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$475.29
Details
Human Maus Unkonjugiert ELISA, FACS, IHC, IHC (p) Human Liver, Hepatocytes: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Maus Unkonjugiert ELISA, FACS, IF/ICC, WB 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details
Rind (Kuh) Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with CRTC1 antibody ABIN214337 at 1:500 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-CRTC1 / MECT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Maus Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Maus Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

Am meisten referenzierte anti-CRTC1 Antikörper

  1. Human Monoclonal CRTC1 Primary Antibody für ICC, FACS - ABIN969066 : Winnes, Mölne, Suurküla, Andrén, Persson, Enlund, Stenman: Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas. in Genes, chromosomes & cancer 2007 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen CRTC1 Interaktionspartner

Human CREB Regulated Transcription Coactivator 1 (CRTC1) Interaktionspartner

  1. Pharmacological inhibition of mTORC1 by rapamycin in PHA (zeige LBR Antikörper)-stimulated PBL reduced viral replication to the level found in unstimulated lymphocytes, indicating that mTORC1 activity supports MV replication as a proviral host factor.

  2. SNP located in CRTC1 has been shown in GWAS studies to be significantly associated with the risk of Barrett's esophagus.

  3. This work reveals a regulatory circuit in which SIK1 (zeige SIK1 Antikörper) suppresses gluconeogenic gene transcription by inducing ubiquitination and degradation of CRTC1.

  4. CRTC1 negatively regulates lipogenic gene expression in liver.

  5. findings suggest further characterization of MECs is needed before considering the CRTC1/3-MAML2 (zeige MAML2 Antikörper) gene fusion as a prognostic biomarker

  6. modulation of rDNA transcription initiation, elongation and rRNA processing is an immediate, co-regulated response to altered amino acid abundance, dependent on both mTORC1 activation of S6K1 (zeige RPS6KB1 Antikörper) and MYC (zeige MYC Antikörper) activity

  7. High TORC1 expression is associated with meningioma and schwannoma.

  8. MECT1-MAML2 (zeige MAML2 Antikörper) fusion transcript is a driver genetic event in the pathogenesis of primary bronchopulmonary mucoepidermoid carcinoma

  9. CRTC1 as new mediator of PGE2 signaling

  10. Consistent with our findings in Drosophila, through the characterization of a wdr24-/- knockout HeLa cell line we determined that Wdr24 promotes lysosome acidification and autophagic flux in mammalian cells

Mouse (Murine) CREB Regulated Transcription Coactivator 1 (CRTC1) Interaktionspartner

  1. Collectively, these findings highlight the male-specific involvement of CRTC1 in the central control of energy balance and circadian locomotor activity.

  2. CRTC1 selectively plays protective role against nonalcoholic fatty liver disease development.CRTC1 also mediates anti-lipogenic effects of bile acid signaling, whereas it is negatively regulated by miR (zeige MLXIP Antikörper)-34a.

  3. the HDAC3 (zeige HDAC3 Antikörper)-N-CoR (zeige NCOR1 Antikörper) corepressor complex leaves the Fgf1b (zeige FGF1 Antikörper) promoter and a complex involving the translocated CRTC1, phosphorylated CREB (zeige CREB1 Antikörper), and histone acetyltransferase (zeige HAT Antikörper) CBP (zeige CREBBP Antikörper) induces transient transcription.

  4. Deletion of Raptor (zeige RPTOR Antikörper) reduced the size of limb bud cells, resulting in overall diminution of the limb bud without affecting skeletal patterning. We then examined the potential role of mTORC1 in chondrogenic differentiation in vitro.

  5. Three mouse CRTCs (Crtc1, Crtc2 (zeige CRTC2 Antikörper) and Crtc3 (zeige CRTC3 Antikörper)) exhibit distinct patterns of 14-3-3 (zeige YWHAQ Antikörper) binding at three conserved sites corresponding to S70, S171 (zeige NUMB Antikörper), and S275 (in CRTC2 (zeige CRTC2 Antikörper)).

  6. The NR2B (zeige GRIN2B Antikörper)-CREB (zeige CREB1 Antikörper)-miR212/132-CRTC1-CREB (zeige CREB1 Antikörper) signal network plays an important role in the regulation of pain.

  7. Findings reveal a critical role of CREB-regulated transcription coactivator 1 (CRTC1) in the hippocampus during associative memory, and provide evidence that CRTC1 deregulation underlies memory deficits during neurodegeneration.

  8. Analysis of the successful model also elucidates two dynamical motifs: neutralization of a negative regulator, which characterizes how Akt (zeige AKT1 Antikörper) indirectly activates mTORC1, and seesaw enzyme regulation, which describes how activated and inhibited states of mTORC1 are controlled in concert to produce a nonlinear, ultrasensitive response

  9. Study suggests that CRTC1 is a key regulator of behavioral and molecular response to antidepressant: CRTC1 is required for complete behavioral antidepressant response and for desipramine-induced expression of Bdnf (zeige BDNF Antikörper) and Nr4a1 (zeige NR4A1 Antikörper)-2. By acting downstream of CRTC1, the HDAC (zeige HDAC3 Antikörper) inhibitor SAHA improves the depressive-like behavior of Crtc1-/- mice.

  10. IL-4 (zeige IL4 Antikörper) signaling co-opts the Akt (zeige AKT1 Antikörper)-mTORC1 pathway to regulate Acly (zeige ACLY Antikörper), a key enzyme in acetyl-CoA (zeige LPCAT1 Antikörper) synthesis, leading to increased histone acetylation and macrophage gene induction.

CRTC1 Antigen-Profil

Protein Überblick

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells (By similarity). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons.

Genbezeichner und Symbole assoziert mit CRTC1

  • CREB regulated transcription coactivator 1 (CRTC1) Antikörper
  • CREB regulated transcription coactivator 1 (Crtc1) Antikörper
  • CREB regulated transcription coactivator 1 (crtc1) Antikörper
  • CREB regulated transcription coactivator 1b (crtc1b) Antikörper
  • AI413414 Antikörper
  • crtc1 Antikörper
  • fc68c05 Antikörper
  • Mect1 Antikörper
  • mKIAA0616 Antikörper
  • pde4cb Antikörper
  • R74955 Antikörper
  • si:ch211-255d18.1 Antikörper
  • si:ch211-255d18.8 Antikörper
  • TORC-1 Antikörper
  • TORC1 Antikörper
  • WAMTP1 Antikörper
  • wu:fc68c05 Antikörper

Bezeichner auf Proteinebene für CRTC1

CREB-regulated transcription coactivator 1 , mucoepidermoid carcinoma translocated protein 1 , transducer of regulated cAMP response element-binding protein (CREB) 1 , TORC-1 , mucoepidermoid carcinoma translocated 1 , mucoepidermoid carcinoma translocated protein 1 homolog , transducer of CREB protein 1 , transducer of regulated cAMP response element-binding protein 1 , CREB regulated transcription coactivator 1 , CREB-regulated transcription coactivator 1-like , CH211-255D18.10 , CH211-255D18.9 , CREB regulated transcription coactivator 1b , cAMP-specific 3',5'-cyclic phosphodiesterase 4C , phosphodiesterase 4C, cAMP-specific b , zfTorc1

GENE ID SPEZIES
23373 Homo sapiens
382056 Mus musculus
510465 Bos taurus
684527 Rattus norvegicus
720274 Macaca mulatta
735806 Pan troglodytes
771015 Gallus gallus
100036611 Xenopus (Silurana) tropicalis
100385682 Callithrix jacchus
100479645 Ailuropoda melanoleuca
100523662 Sus scrofa
100548464 Meleagris gallopavo
571344 Danio rerio
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