Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
CMTM6 belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. Zusätzlich bieten wir Ihnen CMTM6 Antikörper (18) und CMTM6 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 31 products:
CMTM6 is present at the cell surface, associates with the PD-L1 (zeige CD274 ELISA Kits) protein, reduces its ubiquitination and increases PD-L1 (zeige CD274 ELISA Kits) protein half-life; CMTM6 enhances the ability of PD-L1 (zeige CD274 ELISA Kits)-expressing tumour cells to inhibit T cells; collectively, our data reveal that PD-L1 (zeige CD274 ELISA Kits) relies on CMTM6/4 to efficiently carry out its inhibitory function, and suggest potential new avenues to block this pathway
CMTM6 depletion, via the reduction of PD-L1 (zeige CD274 ELISA Kits), significantly alleviates the suppression of tumour-specific T cell activity in vitro and in vivo; findings provide insights into the biology of PD-L1 (zeige CD274 ELISA Kits) regulation, identify a previously unrecognized master regulator of this critical immune checkpoint and highlight a potential therapeutic target to overcome immune evasion by tumour cells
Bioinformatics based on CKLF2 (zeige CKLF ELISA Kits) cDNA and protein sequences in combination with experimental validation identified CKLFSF1 (zeige CMTM1 ELISA Kits)-8 gene clusters, between the SCY (zeige CELSR1 ELISA Kits) and the TM4SF (zeige TSPAN1 ELISA Kits) gene families. The 8 family members were cloned and characterized.
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown.
CKLF-like MARVEL transmembrane domain-containing protein 6
, CKLF-like MARVEL transmembrane domain containing 6
, chemokine-like factor superfamily 6
, chemokine-like factor superfamily member 6
, chemokine-like factor super family 6