CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) ELISA Kits

The protein encoded by CDKAL1 is a member of the methylthiotransferase family. Zusätzlich bieten wir Ihnen CDKAL1 Antikörper (42) und CDKAL1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CDKAL1 54901 Q5VV42
CDKAL1 68916 Q91WE6
Anti-Ratte CDKAL1 CDKAL1 361243  
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Weitere ELISA Kits für CDKAL1 Interaktionspartner

Human CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) Interaktionspartner

  1. family-based GWAS of imputed SNPs revealed novel genomic variants in (or near) PTPRG (zeige PTPRG ELISA Kits), OSBPL6 (zeige OSBPL6 ELISA Kits), and PDCL3 (zeige PDCL3 ELISA Kits) that influence risk for Alzheimer's Disease. rs7609954 in the gene PTPRG (zeige PTPRG ELISA Kits), rs1347297 in the gene OSBPL6 (zeige OSBPL6 ELISA Kits), and rs1513625 near PDCL3 (zeige PDCL3 ELISA Kits). In addition, rs72953347 in OSBPL6 (zeige OSBPL6 ELISA Kits) and two SNPs in the gene CDKAL1 showed marginally significant association with LOAD (rs10456232, P-value=4.76 x 10-7; rs62400067, P-value=3.54 x 10-7).

  2. The multivariate logistic regression analysis with reference to both alleles and genotypes of CDKAL1 SNPs showed significant association, suggesting an important role for this gene in the T2DM pathophysiology. INTERPRETATION & CONCLUSIONS: A significant association was seen of all the three SNPs of CDKAL1 and CDKN2A/B genes with T2DM but none of the two SNPs of HHEX (zeige HHEX ELISA Kits).

  3. Study provides evidence that SNPs of JMJD1C and KCNQ1 (zeige KCNQ1 ELISA Kits) are prospectively associated with the risk of type 2 diabetes (T2D) in Korean population. Additionally, CDKAL1 may not be associated with T2D onset over the age of 40.

  4. Our results suggest that rs6908425 in CDKAL1 is associated with the risk of developing SAPHO in Han Chinese populations. People who carry the risk allele T of rs6908425 might be more prone to developing SAPHO syndrome.

  5. We investigated the association between 8 single-nucleotide polymorphisms (SNPs) at 3 genetic loci (CDKAL1, CDKN2A/2B and FTO (zeige FTO ELISA Kits)) with type 2 diabetes (T2D) in a Uyghur population

  6. our data suggested that CDKAL1 gene variants have a significant effect on the response to anti-TNF (zeige TNF ELISA Kits) therapies among Psoriasis patients

  7. Risk alleles for 6 loci increased glucose levels from birth to 5 years of age (ADCY5 (zeige ADCY5 ELISA Kits), ADRA2A (zeige ADRA2A ELISA Kits), CDKAL1, CDKN2A/B, GRB10 (zeige GRB10 ELISA Kits), and TCF7L2 (zeige TCF7L2 ELISA Kits)

  8. rs10946398 associated with markers of impaired insulin (zeige INS ELISA Kits) secretion

  9. We observed novel selection signals in CDKAL1 and NEGR1 (zeige NEGR1 ELISA Kits), well-known diabetes and obesity susceptibility genes

  10. study found SNP rs7754840 in CDKAL1, rs864745 in JAZF1 (zeige JAZF1 ELISA Kits), and rs35767 in IGF1 (zeige IGF1 ELISA Kits) might serve as potential susceptibility loci for type 2 diabetes in the Uyghur population

Mouse (Murine) CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) Interaktionspartner

  1. CDKAL1 may affect such compensatory mechanisms regulating glucose homeostasis through interaction with diet

  2. Knockout mice with pancreatic beta-cell-specific lack of cdkal1 show pancreatic islet hypertrophy and impaired blood glucose control.

  3. Data show that Cdkal1 is a mammalian methylthiotransferase that biosynthesizes 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) in tRNA(Lys (zeige LYZ ELISA Kits))(UUU) and that it is required for the accurate translation of AAA (zeige AAAS ELISA Kits) and AAG codons.

  4. CDKAL1 controls first-phase insulin (zeige INS ELISA Kits) exocytosis in beta cells by facilitating ATP generation, K(ATP) channel responsiveness and the subsequent activity of Ca(2 (zeige CA2 ELISA Kits)+) channels through pathways other than CDK5 (zeige CDK5 ELISA Kits)-mediated regulation

CDKAL1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes.

Genbezeichner und Symbole assoziert mit CDKAL1

  • CDK5 regulatory subunit associated protein 1 like 1 (CDKAL1) Antikörper
  • CDK5 regulatory subunit associated protein 1-like 1 (cdkal1) Antikörper
  • CDK5 regulatory subunit associated protein 1-like 1 S homeolog (cdkal1.S) Antikörper
  • threonylcarbamoyladenosine tRNA methylthiotransferase (LOC587594) Antikörper
  • CDK5 regulatory subunit associated protein 1-like 1 (Cdkal1) Antikörper
  • 1190005B03Rik Antikörper
  • 6620401C13Rik Antikörper
  • MGC76088 Antikörper
  • MGC78779 Antikörper
  • zgc:65864 Antikörper

Bezeichner auf Proteinebene für CDKAL1

CDK5 regulatory subunit-associated protein 1-like 1 , tRNA-t(6)A37 methylthiotransferase , threonylcarbamoyladenosine tRNA methylthiotransferase , CDK5 regulatory subunit associated protein 1-like 1

100052309 Equus caballus
393600 Danio rerio
394802 Xenopus (Silurana) tropicalis
420823 Gallus gallus
432014 Xenopus laevis
530159 Bos taurus
587594 Strongylocentrotus purpuratus
747778 Pan troglodytes
100024680 Monodelphis domestica
54901 Homo sapiens
488240 Canis lupus familiaris
68916 Mus musculus
361243 Rattus norvegicus
100512355 Sus scrofa
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