CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) ELISA Kits

The protein encoded by CDKAL1 is a member of the methylthiotransferase family.

list all ELISA KIts Gen GeneID UniProt
Anti-Human CDKAL1 CDKAL1 54901 Q5VV42
Anti-Maus CDKAL1 CDKAL1 68916 Q91WE6
Anti-Ratte CDKAL1 CDKAL1 361243  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
Maus < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage

Weitere ELISA Kits für CDKAL1 Interaktionspartner

Human CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) Interaktionspartner

  1. More CDKAL1 variants are required to validate the association between CDKAL1 and gestational glycemic traits.

  2. Forced MT1E (zeige MT1E ELISA Kits) expression rescues both hypersensitivity of CDKAL1 mutant cells to glycolipotoxicity and pancreatic beta-cell dysfunction in vitro and in vivo.

  3. CDKAL1 gene is associated with development of type 2 diabetes. For the HHEX/IDE (zeige IDE ELISA Kits) locus, such an association is absent.

  4. family-based GWAS of imputed SNPs revealed novel genomic variants in (or near) PTPRG (zeige PTPRG ELISA Kits), OSBPL6, and PDCL3 that influence risk for Alzheimer's Disease. rs7609954 in the gene PTPRG (zeige PTPRG ELISA Kits), rs1347297 in the gene OSBPL6, and rs1513625 near PDCL3. In addition, rs72953347 in OSBPL6 and two SNPs in the gene CDKAL1 showed marginally significant association with LOAD (rs10456232, P-value=4.76 x 10-7; rs62400067, P-value=3.54 x 10-7).

  5. The multivariate logistic regression analysis with reference to both alleles and genotypes of CDKAL1 SNPs showed significant association, suggesting an important role for this gene in the T2DM pathophysiology. INTERPRETATION & CONCLUSIONS: A significant association was seen of all the three SNPs of CDKAL1 and CDKN2A/B genes with T2DM but none of the two SNPs of HHEX.

  6. Study provides evidence that SNPs of JMJD1C and KCNQ1 (zeige KCNQ1 ELISA Kits) are prospectively associated with the risk of type 2 diabetes (T2D) in Korean population. Additionally, CDKAL1 may not be associated with T2D onset over the age of 40.

  7. Our results suggest that rs6908425 in CDKAL1 is associated with the risk of developing SAPHO in Han Chinese populations. People who carry the risk allele T of rs6908425 might be more prone to developing SAPHO syndrome.

  8. We investigated the association between 8 single-nucleotide polymorphisms (SNPs) at 3 genetic loci (CDKAL1, CDKN2A/2B and FTO (zeige FTO ELISA Kits)) with type 2 diabetes (T2D) in a Uyghur population

  9. our data suggested that CDKAL1 gene variants have a significant effect on the response to anti-TNF (zeige TNF ELISA Kits) therapies among Psoriasis patients

  10. Risk alleles for 6 loci increased glucose levels from birth to 5 years of age (ADCY5 (zeige ADCY5 ELISA Kits), ADRA2A (zeige ADRA2A ELISA Kits), CDKAL1, CDKN2A/B, GRB10 (zeige GRB10 ELISA Kits), and TCF7L2 (zeige TCF7L2 ELISA Kits)

Mouse (Murine) CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) Interaktionspartner

  1. CDKAL1 may affect such compensatory mechanisms regulating glucose homeostasis through interaction with diet

  2. Knockout mice with pancreatic beta-cell-specific lack of cdkal1 show pancreatic islet hypertrophy and impaired blood glucose control.

  3. Data show that Cdkal1 is a mammalian methylthiotransferase that biosynthesizes 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) in tRNA(Lys (zeige LYZ ELISA Kits))(UUU) and that it is required for the accurate translation of AAA (zeige AAAS ELISA Kits) and AAG codons.

  4. CDKAL1 controls first-phase insulin (zeige INS ELISA Kits) exocytosis in beta cells by facilitating ATP generation, K(ATP) channel responsiveness and the subsequent activity of Ca(2 (zeige CA2 ELISA Kits)+) channels through pathways other than CDK5 (zeige CDK5 ELISA Kits)-mediated regulation

CDKAL1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes.

Genbezeichner und Symbole assoziert mit CDKAL1

  • CDK5 regulatory subunit associated protein 1 like 1 (CDKAL1) Antikörper
  • CDK5 regulatory subunit associated protein 1-like 1 (cdkal1) Antikörper
  • CDK5 regulatory subunit associated protein 1-like 1 S homeolog (cdkal1.S) Antikörper
  • threonylcarbamoyladenosine tRNA methylthiotransferase (LOC587594) Antikörper
  • CDK5 regulatory subunit associated protein 1-like 1 (Cdkal1) Antikörper
  • 1190005B03Rik Antikörper
  • 6620401C13Rik Antikörper
  • MGC76088 Antikörper
  • MGC78779 Antikörper
  • zgc:65864 Antikörper

Bezeichner auf Proteinebene für CDKAL1

CDK5 regulatory subunit-associated protein 1-like 1 , tRNA-t(6)A37 methylthiotransferase , threonylcarbamoyladenosine tRNA methylthiotransferase , CDK5 regulatory subunit associated protein 1-like 1

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