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The protein encoded by CD96 belongs to the immunoglobulin superfamily. Zusätzlich bieten wir Ihnen CD96 Antikörper (89) und CD96 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.
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Blockade of CD96 completely restored the expansion an (zeige IL9 Proteine)d inflammatory properties o (zeige IFNG Proteine)f CD96(high) Th9 cells
These results suggest a function of the CD96/CD155 (zeige PVR Proteine)-adhesion system in T cell biology.
CD96-driven adhesion to CD155 (zeige PVR Proteine) may be crucial in developmental processes
Lower CD96 expression was also observed in human IL-9 (zeige IL9 Proteine)(+) compared with IFN-gamma (zeige IFNG Proteine)(+) T cells
Blocking CD96 or TIGIT (zeige TIGIT Proteine) with mAbs has been shown to improve tumor control in mice.
CD96 and CD123 (zeige IL3RA Proteine) are expressed in bone marrow cells of patients with myelodysplastic syndromes
In the present study we analyzed the expression of four cell surface antigens relevant to human hematopoiesis-CD90 (zeige THY1 Proteine), CD96, CD117, and CD123 (zeige IL3RA Proteine)-in bone marrow from pediatric acute myeloid leukemia (zeige BCL11A Proteine) patients and normal control subjects.
down-regulation of CD96 is an important aspect of HIV-1 pathogenesis and differential expression is related to cell effector functions and HIV-1 disease course.
CD96 could serve as a target structure for effector cell-mediated lysis.
The positive expression of CD96 on bone marrow hematopoietic stem cells in patients with acute leukemia may be associated with primary drug resistance, relapse and progression.
CD96 promotes natural killer (NK) cell adhesion to target cells expressing the poliovirus receptor (PVR (zeige PVR Proteine)), stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR (zeige PVR Proteine) from target cells.
CD96 is a cell surface marker present on many acute myeloid leukemia (zeige BCL11A Proteine) leukemic stem cells
The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
T cell activation, increased late expression
, T-cell surface protein tactile
, cell surface antigen CD96
, t cell-activated increased late expression protein
, CD96 antigen