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The protein encoded by CD96 belongs to the immunoglobulin superfamily. Zusätzlich bieten wir Ihnen CD96 Antikörper (89) und CD96 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
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Lower CD96 expression was also observed in human IL-9(+) compared with IFN-gamma(+) T cells
Blocking CD96 or TIGIT with mAbs has been shown to improve tumor control in mice.
CD96 and CD123 are expressed in bone marrow cells of patients with myelodysplastic syndromes
In the present study we analyzed the expression of four cell surface antigens relevant to human hematopoiesis-CD90, CD96, CD117, and CD123-in bone marrow from pediatric acute myeloid leukemia patients and normal control subjects.
down-regulation of CD96 is an important aspect of HIV-1 pathogenesis and differential expression is related to cell effector functions and HIV-1 disease course.
CD96 could serve as a target structure for effector cell-mediated lysis.
The positive expression of CD96 on bone marrow hematopoietic stem cells in patients with acute leukemia may be associated with primary drug resistance, relapse and progression.
CD96 promotes natural killer (NK) cell adhesion to target cells expressing the poliovirus receptor (PVR), stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells.
CD96 is a cell surface marker present on many acute myeloid leukemia leukemic stem cells
CD96-driven adhesion to CD155 may be crucial in developmental processes
The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
T cell activation, increased late expression
, T-cell surface protein tactile
, cell surface antigen CD96
, t cell-activated increased late expression protein
, CD96 antigen