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Plays a role in B-cell proliferation and differentiation.. Zusätzlich bieten wir Ihnen CD72 Antikörper (160) und CD72 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.
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CD72 appears to specifically inhibit B cell response to the endogenous TLR7 (zeige TLR7 Proteine) ligand Sm/RNP (zeige RNPC3 Proteine).
CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcepsilonRIalpha.
CD5 (zeige CD5 Proteine) and CD72 play a critical role in maintaining regulatory T and B cell homeostasis
These results strongly suggest that the Cd72(c) is a crucial modifier gene that regulates Fas(lpr (zeige FAS Proteine))-induced autoimmune disease due to its reduced activity of B cell signal regulation.
Cd72 polymorphism affects susceptibility to lupus phenotypes.
Inhibitory coreceptors CD72 and CD22 (zeige CD22 Proteine) are responsible for setting the requirement of CD40 (zeige CD40 Proteine) signaling for survival and proliferation of antigen-stimulated spleen B cells.
results strongly suggest that the apoptosis preventing signal evoked by CD72 ligation is delivered through the pathway of NF-kappaB (zeige NFKB1 Proteine), c-Myc (zeige MYC Proteine), p27(Kip1 (zeige CDKN1B Proteine)) and cyclin (zeige PCNA Proteine)
Strength of B-cell antigen receptor signals is strictly tuned by the interaction of CD100 (zeige SEMA4D Proteine) with CD72; this interaction is essential for maintaining immunological homeostasis as well as generating a proper immune response.
CD72 plays a dominant role as a negative regulator of BCR (zeige BCR Proteine) signaling in primary mature B lymphocytes.
CD72 is required to maintain B cell anergy and functions as a regulator of peripheral B cell tolerance
Interferon-alpha (zeige IFNA Proteine)-induced CD100 (zeige SEMA4D Proteine) expression on naive CD8 (zeige CD8A Proteine)(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.
Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis
CD72 expression on activated B cells of SLE patients was significantly lower than that of normal controls. sema3A (zeige SEMA3A Proteine) enhanced CD72 expression of B cells, but it was still lower in SLE patients than in normal individuals.
data demonstrated aberrant expression of CD72 exists on B cells of myasthenia gravis and multiple sclerosis patients and expression level of CD72 molecule has a significantly negative correlation with anti-AchR antibody levels in myasthenia gravis
CD72 mRNA expression level correlates with Sema4D (zeige SEMA4D Proteine) expression in peripheral blood mononuclear cells in immune thrombocytopenia.
CD100 (zeige SEMA4D Proteine), CD72 and CD45 (zeige PTPRC Proteine) were expressed in placenta and exhibited different mRNA and protein levels in normal pregnancy and miscarriage. Protein levels were highly dysregulated around 10 weeks of gestation in first and second miscarriage placentas.
CD100 (zeige SEMA4D Proteine)-CD72 interaction can be the mechanism by which NK cell communicate with B cells.
Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine (zeige CCL1 Proteine) production.
results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B-232Thr, possibly by increasing the AS isoform of CD72
CD72 is a key molecule in regulating mature B cell differentiation; CD72 signaling reduces the expression of X-box binding protein 1 (zeige XBP1 Proteine) in B cells
Plays a role in B-cell proliferation and differentiation.
B-cell differentiation antigen CD72
, lymphocyte antigen 32
, CD72 antigen