CD59a Antigen (CD59A) ELISA Kits

Potent inhibitor of the complement membrane attack complex (MAC) action. Zusätzlich bieten wir Ihnen CD59a Antigen Antikörper (8) und CD59a Antigen Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CD59A 12509 O55186
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
  96 Tests 2 bis 3 Tage

Weitere ELISA Kits für CD59a Antigen Interaktionspartner

Mouse (Murine) CD59a Antigen (CD59A) Interaktionspartner

  1. Data (including data from studies using knockout mice) suggest that CD59a, CD59b, and ApoE are involved in development of diabetes-induced atherosclerosis; here, deficiency of CD59a/CD59b (in ApoE deficient mice) accelerates development of atherosclerosis in mice with type 1 diabetes. (CD59a = CD59a antigen; CD59b = CD59b antigen; ApoE = apolipoprotein E)

  2. Varicella-zoster virus infection upregulates host CD59 expression in a tissue-specific manner.

  3. This study support a role of Cd59a in controlling the innate immune status of the RPE-choroidal complex and emphasizes the particular vulnerability of this ocular compartment to the dysregulation of alternative complement pathway during aging

  4. results implicate CD59 as an important modulator of the immune response in NMO, and provide a novel animal model of NMO that closely recapitulates human NMO pathology.

  5. Soluble forms of CD59 (sCD59) have been investigated in mouse laser-induced choroidal neovascularization, a model for "wet" age related macular degeneration.

  6. both CD59 and C-PC could inhibit the progress of atherosclerosis, and the anti-atherosclerotic effects of C-PC might be fulfilled by promoting CD59 expression, preventing smooth muscle cell proliferation and the apoptosis of endothelial cells

  7. CD59a inhibits systemic autoimmunity in MRL/lpr mice through a complement-independent mechanism.

  8. While the connection between CFH deficiency and failure to upregulate CD59a remains unknown, these results suggest that expression of CD59 is tissue-specific and that neuroretinal regulation depends on CFH.

  9. Actively immunized experimental autoimmune myasthenia gravis mice deficient in either CD55 or CD59 showed significant differences in adaptive immune responses and worsened disease outcome associated with increased levels of serum cytokines, modified production of acetylcholine receptor antibodies, and more complement deposition at the neuromuscular junction.

  10. HBx can up-regulate CD59 and Crry expression in podocytes through activating the P38 pathway.

  11. CD59 has a role in growth of the choroidal neovascular complex in mice

  12. This study that CD59a protects against ischemic brain damage, but depending on the gender and the stroke model used.

  13. Complement regulator CD59 protects against angiotensin II-induced abdominal aortic aneurysms in mice.

  14. Genomic structure, functional comparison, and tissue distribution of mouse Cd59a and Cd59b.

  15. Results of studies of autoantibody-mediated nephritis in CD59a knockout mice show that the activity of CD59 becomes clearly apparent in the absence of decay-accelerating factor, and thus the activities of both regulators are essential.

  16. CD59 acts synergistically with CD55 to inhibit complement-mediated renal ischemia-reperfusion injury.

  17. CD59a deficiency exacerbates ischemia-reperfusion injury in mice

  18. CD59a is the physiologically relevant regulator of membrane attack complex assembly in the majority of mouse tissues.

  19. Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis.

  20. Reported the mapping of promoter regions of both mouse Cd59a and Cd59b genes and identified that each Cd59 gene expresses two different tissue-specific transcripts that differ at their 5'ends.

CD59a Antigen (CD59A) Antigen-Profil

Beschreibung des Gens

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity).

Genbezeichner und Symbole assoziert mit CD59a Antigen (CD59A) ELISA Kits

  • CD59a antigen (Cd59a) Antikörper
  • AA987121 Antikörper
  • Cd59 Antikörper
  • protectin Antikörper

Bezeichner auf Proteinebene für CD59a Antigen (CD59A) ELISA Kits

CD59 antigen , CD59A glycoprotein , MAC-IP , MAC-inhibitory protein , MACIF , membrane attack complex inhibition factor

12509 Mus musculus
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