anti-CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Antikörper

CD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. Zusätzlich bieten wir Ihnen CD244 Proteine (27) und CD244 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CD244 51744 Q9BZW8
CD244 64025 Q9JLM2
CD244 18106 Q07763
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Top anti-CD244 Antikörper auf antikoerper-online.de

Showing 10 out of 128 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert FACS   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$116.64
Details
Human Ziege PE FACS Detection of 2B4/CD244/SLAMF4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$293.25
Details
Human Ziege Unkonjugiert IP, ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Rat Serum; Lane2: Rat Kidney Tissue. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$360.00
Details
Maus Ziege Biotin FACS, IHC, WB   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
$446.20
Details
Maus Ziege Unkonjugiert CyTOF, FACS, IHC, WB   100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Ziege Unkonjugiert Agon, CyTOF, ELISA (Capture), FACS, IHC, WB 2B4/CD244/SLAMF4 in Human Spleen. 2B4/CD244/SLAMF4 was detected in immersion fixed paraffin-embedded sections of human spleen using Goat Anti-Human 2B4/CD244/SLAMF4 Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to splenocytes. Detection of 2B4/CD244/SLAMF4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Ziege Unkonjugiert IP, ELISA 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert IHC (p) A549 cells probed with Rabbit Anti-CD244 Polyclonal Antibody (ABIN740730) at 1:50 for 60 minutes followed by incubation with Goat Anti-Rabbit IgG FITC conjugated secondary at 1:100 (green) for 40 minutes compared to control cells (blue). Paraformaldehyde-fixed, paraffin embedded human kidney, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CD244 Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C, followed by a conjugated secondary for 90 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details

CD244 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CD244 Antikörper

  1. Human Monoclonal CD244 Primary Antibody für FACS - ABIN2689111 : Mathew, Garni-Wagner, Land, Takashima, Stoneman, Bennett, Kumar: Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal CD244 Primary Antibody für FACS - ABIN2479431 : Gluckman, Jolivet, Scrobohaci, Devergie, Traineau, Bourdeau-Esperou, Lehn, Faure, Drouet: Use of prostaglandin E1 for prevention of liver veno-occlusive disease in leukaemic patients treated by allogeneic bone marrow transplantation. in British journal of haematology 1990 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal CD244 Primary Antibody für FACS, IP - ABIN2479426 : Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CD244 Primary Antibody für FACS, IP - ABIN2479430 : Raziorrouh, Schraut, Gerlach, Nowack, Grüner, Ulsenheimer, Zachoval, Wächtler, Spannagl, Haas, Diepolder, Jung: The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function. in Hepatology (Baltimore, Md.) 2010 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal CD244 Primary Antibody für FACS - ABIN2479428 : Bengsch, Martin, Thimme: Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation. in Journal of hepatology 2014 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal CD244 Primary Antibody für Agon, CyTOF - ABIN5012830 : Roda-Navarro, Vales-Gomez, Chisholm, Reyburn: Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal CD244 Primary Antibody für IHC (p) - ABIN740730 : Peiffer, Wang, Zimmerman, Ransom, Carmella, Kuo, Chen, Oshima, Huang, Hecht, Stoner: Dietary Consumption of Black Raspberries or Their Anthocyanin Constituents Alters Innate Immune Cell Trafficking in Esophageal Cancer. in Cancer immunology research 2016 (PubMed)

  8. Mouse (Murine) Polyclonal CD244 Primary Antibody für FACS, IHC - ABIN4898999 : Cao, Wagers, Karsunky, Zhao, Reeves, Wong, Stevenson, Weissman, Contag: Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. in Blood 2008 (PubMed)

  9. Mouse (Murine) Polyclonal CD244 Primary Antibody für CyTOF, FACS - ABIN4899297 : Wahle, Paraiso, Kendig, Lawrence, Chen, Wu, Kerr: Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)

  10. Human Polyclonal CD244 Primary Antibody für FACS - ABIN4895306 : Mattiola, Pesant, Tentorio, Molgora, Marcenaro, Lugli, Locati, Mavilio: Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

Weitere Antikörper gegen CD244 Interaktionspartner

Human CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Interaktionspartner

  1. The present study provides further insights into the role of the 2B4-CD48 (zeige CD48 Antikörper) interaction in the fine regulation of CD8 (zeige CD8A Antikörper)(+) T-cell effector function upon antigenic stimulation.

  2. Data show that 2B4 not only can bind to CD48 (zeige CD48 Antikörper) in trans but also interacts with CD48 (zeige CD48 Antikörper) in cis (zeige CISH Antikörper) by using the same binding interface. Also, the results demonstrated that constitutive phosphorylation of 2B4 occurs only in the presence of CD48 (zeige CD48 Antikörper), and that cis (zeige CISH Antikörper) binding is sufficient to induce substantial levels of baseline phosphorylation.

  3. 2B4 expression is increased on CD4 (zeige CD4 Antikörper)+ T cells in septic patients

  4. Self-iNKR(-) NK cells in X-linked lymphoproliferative disease 1 patients are functional even in resting conditions, suggesting a role of the inhibitory 2B4/CD48 (zeige CD48 Antikörper) pathway in the education process during NK-cell maturation.

  5. our results provide strong evidence that CD244 co-operates with c-Kit (zeige KIT Antikörper) to regulate leukemogenesis through SHP-2 (zeige PTPN11 Antikörper)/p27 (zeige PAK2 Antikörper) signaling.

  6. SLAMF4 gene and surface protein expression was down-regulated in CD8 (zeige CD8A Antikörper)+ T cells from SLE patients compared with that in cells obtained from healthy donors. SLAMF4+ effector memory cells produced more granzyme B and perforin (zeige PRF1 Antikörper) than SLAMF4- cells.

  7. GSK-3 undergoes inhibitory phosphorylation at regulatory serine residues by the engagement of NKG2D (zeige KLRK1 Antikörper) and 2B4, either individually or in combination.

  8. Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8 (zeige CD8A Antikörper)+ T Cell Hyporesponsiveness to Alloantigen

  9. CD8 (zeige CD8A Antikörper)(+) T cells require 2B4 for Epstein-Barr virus-specific immune control, because 2B4 blockade after CD8 (zeige CD8A Antikörper)(+) T-cell depletion did not further aggravate symptoms of the infection.

  10. CD244 expression/signaling in tuberculosis correlates with high levels of a long noncoding RNA (lncRNA)-BC050410 [named as lncRNA-AS-GSTT1(1 (zeige GSTT1 Antikörper)-72) or lncRNA-CD244] in the CD244(+)CD8 (zeige CD8A Antikörper)(+) T-cell subpopulation.

Mouse (Murine) CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Interaktionspartner

  1. 2B4 expression is increased on CD4 (zeige CD4 Antikörper)+ T cells in septic animals

  2. 2B4 dampens T-independent B cell responses.

  3. DCs from CD244(-/-) mice elicited increased NK cell activation in vitro. These data add CD244 to a growing list of immuno-modulatory receptors found on DCs.

  4. Data show that enforced expression of inhibitor of differentiation protein Id3 (zeige ID3 Antikörper) specifically increased the persistence of Cd244 protein 2B4(+) virus-specific CD8 (zeige CD8A Antikörper)(+) T cells.

  5. Molecular dynamic simulation explains unbinding and unfolding of CD48 (zeige CD48 Antikörper)-2B4 protein complexes.

  6. Signaling via SLAMF4 controls expansion of cytotoxic CD8alphabeta(+) IELs, which regulate the reversible depletion of lamina propria phagocytes and inflammation in the small intestine.

  7. CD244 (2B4) has a regulatory effect on mast cells and eosinophils in murine allergic inflammation.

  8. NKG2D (zeige KLRK1 Antikörper) ligation relieves 2B4-mediated NK-cell self-tolerance in mice.

  9. blockade of CD28 (zeige CD28 Antikörper) signals in the presence of preserved CTLA-4 (zeige CTLA4 Antikörper) signals results in the unique up-regulation of 2B4 on primary CD8 (zeige CD8A Antikörper)(+) effectors, and that this 2B4 expression plays a critical functional role in controlling antigen-specific T8 cell responses

  10. In the absence of SAP (zeige APCS Antikörper), signaling through the SLAM (zeige SLAMF1 Antikörper) family members Ly108 (zeige SLAMF6 Antikörper) and 2B4 resulted in increased recruitment of the SHP-1 (zeige PTPN6 Antikörper) phosphatase, associated with altered SHP-1 (zeige PTPN6 Antikörper) localization and decreased activation of Src (zeige SRC Antikörper) kinases at the synapse.

CD244 Antigen-Profil

Protein Überblick

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CD244

  • CD244 molecule (CD244) Antikörper
  • CD244 molecule (Cd244) Antikörper
  • CD244 natural killer cell receptor 2B4 (Cd244) Antikörper
  • 2B4 Antikörper
  • C9.1 Antikörper
  • CD244 Antikörper
  • F730046O15Rik Antikörper
  • Ly90 Antikörper
  • NAIL Antikörper
  • NKR2B4 Antikörper
  • Nmrk Antikörper
  • SLAMF4 Antikörper

Bezeichner auf Proteinebene für CD244

CD244 molecule, natural killer cell receptor 2B4 , natural killer cell receptor 2B4 , NK cell activation inducing ligand NAIL , NK cell activation-inducing ligand , NK cell type I receptor protein 2B4 , SLAM family member 4 , h2B4 , signaling lymphocytic activation molecule 4 , CD244 natural killer cell receptor 2B4 , NKR2B4 , non MHC restricted killing associated , non-MHC restricted killing associated , transmembrane NK cell receptor 2B4 , NK cell receptor 2B4

GENE ID SPEZIES
488644 Canis lupus familiaris
513468 Bos taurus
100594419 Nomascus leucogenys
51744 Homo sapiens
64025 Rattus norvegicus
18106 Mus musculus
Ausgewählte Anbieter für anti-CD244 (CD244) Antikörper
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