C1GALT1-Specific Chaperone 1 (C1GALT1C1) ELISA Kits

C1GALT1C1 encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. Zusätzlich bieten wir Ihnen C1GALT1-Specific Chaperone 1 Antikörper (16) und C1GALT1-Specific Chaperone 1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
C1GALT1C1 29071 Q96EU7
C1GALT1C1 59048 Q9JMG2
C1GALT1C1 302499 Q499P3
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Weitere ELISA Kits für C1GALT1-Specific Chaperone 1 Interaktionspartner

Human C1GALT1-Specific Chaperone 1 (C1GALT1C1) Interaktionspartner

  1. The data suggest that hypermethylation of the Cosmc promoter may induce the expression of Tn antigen in activated T cells.

  2. results provide new structure-function insight to Cosmc, indicate that Cosmc behaves as a modular protein and suggests points of modulation or regulation of in vivo chaperone function

  3. Data indicate that mRNA levels of both core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase (zeige GGTA1 ELISA Kits), 1 (C1GALT1 (zeige C1GALT1 ELISA Kits)) and C1GALT1-specific chaperone 1 protein (C1GALT1C1) determine the rate of secretion of galactose-deficient IgA1 (Gd-IgA1) in IgA1-producing cells.

  4. The terminal glycosylation of secreted IgA1 was altered in response to TGFbeta1 (zeige TGFB1 ELISA Kits). TGFbeta1 (zeige TGFB1 ELISA Kits) stimulation significantly decreased the mRNA levels of C1GalT1 (zeige C1GALT1 ELISA Kits) and Cosmc. TGFbeta1 (zeige TGFB1 ELISA Kits) may be key in controlling the glycosylation of IgA1, in part via the downregulation of C1GalT1 (zeige C1GALT1 ELISA Kits) and Cosmc.

  5. mutations c.393T>A and c.72A>G in the exon region of Cosmc gene in children with Henoch-Schonlein purpura (HSP) are not associated with the onset of Henoch-Schonlein purpura

  6. Data suggest that patients with IgA nephropathy exhibit higher microRNA-374b in B cells compared to controls; microRNA-374b appears to target PTEN (phosphatase and tensin homolog) and Cosmc (C1GALT1 specific chaperone 1) proteins.

  7. These results indicate that Tn antigens expression and T-synthase (zeige C1GALT1 ELISA Kits) inactivity in HT-29-Tn+ cells can be related to the absence of the Cosmc gene coding sequence in Cosmc active alleles

  8. the impact of COSMC mediated Tn antigen expression in two human pancreatic ductal adenocarcinoma cell lines on cellular oncogenic properties, were investigated.

  9. hypermethylation of Cosmc promoter region could be a key mechanism for the reduction of Cosmc mRNA expression in IgAN lymphocytes with associated increase in aberrantly glycosylated IgA1

  10. Cosmc and T-synthase (zeige C1GALT1 ELISA Kits) are transcriptionally regulated at a basal level by the specificity protein/Kruppel-like transcription factor (zeige KLF4 ELISA Kits) family of members.

Mouse (Murine) C1GALT1-Specific Chaperone 1 (C1GALT1C1) Interaktionspartner

  1. Cosmc is an essential chaperone for correct protein O-glycosylation.

  2. a somatic mutation in the chaperone gene Cosmc abolished function of a glycosyltransferase, disrupting O-glycan Core 1 synthesis & creating a tumor-specific glycopeptidic neo-epitope consisting of a monosaccharide and a specific wild-type protein sequence

C1GALT1-Specific Chaperone 1 (C1GALT1C1) Antigen-Profil

Beschreibung des Gens

This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Genbezeichner und Symbole assoziert mit C1GALT1C1

  • C1GALT1-specific chaperone 1 (c1galt1c1) Antikörper
  • C1GALT1 specific chaperone 1 (C1GALT1C1) Antikörper
  • C1GALT1 specific chaperone 1 (c1galt1c1) Antikörper
  • C1GALT1 specific chaperone 1 L homeolog (c1galt1c1.L) Antikörper
  • C1GALT1-specific chaperone 1 (C1galt1c1) Antikörper
  • 1500002I11Rik Antikörper
  • AB030184 Antikörper
  • C1GalT2 Antikörper
  • C38H2-L1 Antikörper
  • C81205 Antikörper
  • Cosmc Antikörper
  • MGC88924 Antikörper
  • MST143 Antikörper
  • RGD1311230 Antikörper
  • TNPS Antikörper
  • wu:fc17f08 Antikörper
  • wu:fc59b02 Antikörper
  • zgc:66375 Antikörper

Bezeichner auf Proteinebene für C1GALT1C1

fc59b02 , core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 2 , C1GALT1-specific chaperone 1 , Core 1 beta3-galactosyltransferase-specific molecular chaperone , C1GALT1-specific chaperone 1-like , c1GALT1-specific chaperone 1-like , C1Gal-T2 , C38H2-like protein 1 , beta 1,3-galactosyltransferase 2 , core 1 beta1,3-galactosyltransferase 2 , core 1 beta3-Gal-T2 , core 1 beta3-galactosyltransferase-specific molecular chaperone , beta1,3-galactosyltransferase 2 , mC1Gal-T2

GENE ID SPEZIES
324052 Danio rerio
422362 Gallus gallus
448225 Xenopus (Silurana) tropicalis
465837 Pan troglodytes
495031 Xenopus laevis
696662 Macaca mulatta
100397132 Callithrix jacchus
100441547 Pongo abelii
100594094 Nomascus leucogenys
29071 Homo sapiens
59048 Mus musculus
302499 Rattus norvegicus
531644 Bos taurus
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