C-Type Lectin Domain Family 4, Member D (CLEC4D) ELISA Kits

CLEC4D encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.

list all ELISA KIts Gen GeneID UniProt
Anti-Human CLEC4D CLEC4D 338339 Q8WXI8
Anti-Maus CLEC4D CLEC4D 17474 Q9Z2H6
Anti-Ratte CLEC4D CLEC4D 362432 Q69FH1
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Top CLEC4D ELISA Kits auf antikoerper-online.de

Showing 2 out of 3 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Human
  96 Tests Anmelden zum Anzeigen 31 bis 41 Tage
$790.05
Details

Weitere ELISA Kits für CLEC4D Interaktionspartner

Human C-Type Lectin Domain Family 4, Member D (CLEC4D) Interaktionspartner

  1. Results show the molecular mechanism of glycolipid recognition through C-type lectin (zeige MBL2 ELISA Kits) receptors, which may provide clues to rational design for effective adjuvants.

  2. CLECSF8 functions as an activation receptor on myeloid cells and associates with a novel adaptor molecule

  3. Cross-linking of the receptor leads to a rapid internalization suggesting that CLECSF8 constitutes and endocytic receptor.

Mouse (Murine) C-Type Lectin Domain Family 4, Member D (CLEC4D) Interaktionspartner

  1. MCL (macrophage C-type lectin) plays a crucial role in killing bacteria during Escherichia coli-induced peritonitis. MCL-deficient mice with E. coli-induced sepsis showed lower survival rates and reduced bacterial clearance when compared with control mice, despite similar levels of proinflammatory cytokine production.

  2. activation of CLRs Dectin-2 (zeige CLEC6A ELISA Kits) and Dectin-3 by fungi infections triggers them for ubiquitination and degradation in a Syk (zeige SYK ELISA Kits)-dependent manner.

  3. The authors report that microbial stimulation triggers Mincle (Clec4e (zeige CLEC4E ELISA Kits)) expression through the myeloid differentiation primary response gene 88 (MyD88 (zeige MYD88 ELISA Kits)) pathway; a process that does not require MCL (Clecsf8, Clec4d). Conversely, they show that MCL is constitutively expressed but retained intracellularly until Mincle (zeige CLEC4E ELISA Kits) is induced, whereupon the receptors form heterodimers which are translocated to the cell surface.

  4. Data show that Mincle (zeige CLEC4E ELISA Kits), the inducible receptor for mycobacterial cord factor, is the key switch for the transition of macrophages from cytokine expression to high nitric oxide production.

  5. MCL regulates the development of vaccine-induced Th17 cells and protective immunity against lethal experimental infection with Blastomyces dermatitidis.

  6. major contributor to activation of innate immunity against M. bovis in experimental model, mirrors Mincle (zeige CLEC4E ELISA Kits) expression

  7. Clecsf8-/- mice exhibit higher bacterial burdens and increased mortality upon Mycobacterium tuberculosis infection.

  8. These results suggest that MCL positively regulates Mincle (zeige CLEC4E ELISA Kits) expression through protein-protein interaction via its stalk region, thereby magnifying Mincle (zeige CLEC4E ELISA Kits)-mediated signaling.

  9. Trehalose 6,6'-dimycolate-induced Mincle expression is dependent on Dectin-3-mediated NF-kappaB activation through the CARD9-BCL10-MALT1 complex.

  10. Compared to their respective homodimers, Dectin-3 and Dectin-2 (zeige CLEC6A ELISA Kits) heterodimers bound alpha-mannans more effectively, leading to potent inflammatory responses against fungal infections.

CLEC4D Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Genbezeichner und Symbole assoziert mit CLEC4D

  • C-type lectin domain family 4 member D (CLEC4D) Antikörper
  • C-type lectin domain family 4 member D (LOC611536) Antikörper
  • C-type lectin domain family 4, member d (Clec4d) Antikörper
  • C-type lectin domain family 4, member D (Clec4d) Antikörper
  • CLEC-6 Antikörper
  • CLEC4D Antikörper
  • CLEC6 Antikörper
  • Clecsf8 Antikörper
  • Mcl Antikörper
  • Mpcl Antikörper

Bezeichner auf Proteinebene für CLEC4D

C-type lectin domain family 4, member D , C-type lectin domain family 4 member D , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8 , C-type lectin receptor , C-type lectin superfamily member 8 , C-type lectin-like receptor 6 , macrophage C-type lectin , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8 , C-type lectin, superfamily member 8 , macrophage-restricted C-type lectin

GENE ID SPEZIES
473405 Pan troglodytes
611536 Canis lupus familiaris
616646 Bos taurus
338339 Homo sapiens
17474 Mus musculus
362432 Rattus norvegicus
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