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BLCAP encodes a tumor suppressor protein that reduces cell growth by stimulating apoptosis.
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Upregulated miR (zeige MLXIP ELISA Kits)-9-3p has a positive role in human MTC (zeige MT1A ELISA Kits) progression by regulating the growth and apoptosis of cancer cells via targeting BLCAP.
Our findings reveal that A-to-I RNA editing events alter the genetically coded amino acid in BLCAP YXXQ motif, which drive the progression of cervical carcinogenesis through regulating STAT3 (zeige STAT3 ELISA Kits) signaling pathway.
data indicates that Blcap is a novel Stat3 (zeige STAT3 ELISA Kits) interaction partner and suggests a role for Blcap in the Stat3 (zeige STAT3 ELISA Kits)-mediated progression of precancerous lesions to invasive tumors of the bladder
the functional association of BLCAP and Rb1 (zeige RB1 ELISA Kits) might play important roles in proliferation and apoptosis of HeLa cells.
Data show that the RNA-edited bladder cancer associated protein (BLCAP) gene may stably promote cell proliferation.
Immunoexpression analysis and prognostic value of BLCAP in breast cancer
observed a general decrease in BLCAP-editing level in astrocytomas, bladder cancer and colorectal cancer when compared with the related normal tissues
Data show that loss of BLCAP expression is associated with tumor progression.
BLCAP may play a role not only in regulating cell proliferation but also in coordinating apoptosis and cell cycle via a novel way independent of p53 (zeige TP53 ELISA Kits) and NF-kappaB (zeige NFKB1 ELISA Kits).
Blcap is imprinted in mouse and human brain, but not in other mouse tissues.
This gene encodes a tumor suppressor protein that reduces cell growth by stimulating apoptosis. The first intron of this gene contains the neuronatin gene, which is imprinted and only expressed from the paternal allele. This gene is imprinted in brain where it is differentially expressed from different promoters. Transcription from the upstream promoter occurs preferentially on the maternal allele, and transcripts are preferentially expressed from the downstream promoter on the paternal allele. Alternative promoters and alternative splicing result in multiple transcript variants that encode the same protein.
bladder cancer-associated protein
, blcap protein
, bladder cancer associated protein
, bladder cancer 10 kDa protein
, bladder cancer related protein (10kD)
, bladder cancer associated protein homolog
, Blcapbladder cancer associated protein homolog
, bladder cancer related protein