anti-Bicaudal C Homolog 1 (Drosophila) (BICC1) Antikörper

BICC1 encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human BICC1 BICC1 80114 Q9H694
Anti-Maus BICC1 BICC1 83675 Q99MQ1
Anti-Ratte BICC1 BICC1 361832  
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Top anti-BICC1 Antikörper auf antikoerper-online.de

Showing 10 out of 57 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of BICC1 Antibody (N-term) (ABIN390954) in HL-60 cell line lysates (35 µg/lane). BICC1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with BICC1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
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Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
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Human Kaninchen Unkonjugiert EIA, WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
$517.00
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Human Kaninchen Unkonjugiert WB 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
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Human Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
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Fledermaus Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
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Fledermaus Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
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Human Kaninchen Alkaline Phosphatase (AP) ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details

Am meisten referenzierte anti-BICC1 Antikörper

  1. Human Polyclonal BICC1 Primary Antibody für WB - ABIN1944768 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal BICC1 Primary Antibody für IHC (p), WB - ABIN390954 : Grupe, Li, Rowland, Nowotny, Hinrichs, Smemo, Kauwe, Maxwell, Cherny, Doil, Tacey, van Luchene, Myers, Wavrant-De Vrièze, Kaleem, Hollingworth, Jehu, Foy, Archer, Hamilton, Holmans, Morris, Catanese et al.: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ... in American journal of human genetics 2005 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen BICC1 Interaktionspartner

Zebrafish Bicaudal C Homolog 1 (Drosophila) (BICC1) Interaktionspartner

  1. These results demonstrate that the function of Bicc1 in the kidney is evolutionarily conserved, thus supporting the use of zebrafish as an alternative in vivo model to study the role of mammalian Bicc1 in renal cyst formation.

Human Bicaudal C Homolog 1 (Drosophila) (BICC1) Interaktionspartner

  1. genetic variants in BICC1 and RASGRF1 are closely associated with high myopia, which appears to be a potential candidate for high myopia in Chinese Han population.

  2. Our findings suggested rs17648524 (intronic RBFOX1 gene) and rs7084402 (7.5kb 5' of the BICC1 gene) showed gender-specific associations with high myopia in the Han Chinese.

  3. Suggest allelic changes in the regulation of the BICC1 gene in amygdala neurones may contribute to mood disorders.

  4. Results provide some support for the involvement of BICC1 and PCLO (zeige PCLO Antikörper) in late-life depressive disorders and preliminary evidence that these genetic variants may also influence brain structural volumes

  5. findings identify a role for increased levels of BICC1 in the pathophysiology of depressive behavior

  6. Polymorphisms in intron 2 of BICC1 are associated with its expression and bone (zeige BEST1 Antikörper) mineral density (BMD)

  7. The minor T-allele of BICC1 has a protective role against major depressive disorder and its known structural and functional brain changes.

  8. The nonsense mutation identified in BICC1 and associated with cystic renal dysplasia results in a complete loss of Wnt (zeige WNT2 Antikörper) inhibitory activity. The point mutation in the SAM (zeige TTN Antikörper) domain results in a 22% loss of activity.

Mouse (Murine) Bicaudal C Homolog 1 (Drosophila) (BICC1) Interaktionspartner

  1. Polymerization is a novel disease-relevant mechanism both to stabilize Bicc1 and to present associated mRNAs in specific silencing platforms.

  2. discovered that loss of the Pkd1 (zeige PKD1 Antikörper) gene product, polycystin-1 (PC1 (zeige PKD1 Antikörper)), whose mutation causes human autosomal dominant polycystic kidney disease (ADPKD), downregulates Bicc1 expression in vitro and in vivo

  3. Bicc1 is a novel regulator of osteoblastogenesis and bone mineral density (BMD (zeige BEST1 Antikörper))

  4. Bicc1 KH domains bind the 3' UTRs of AC6 (zeige ADCY6 Antikörper) and PKIa (zeige PKIA Antikörper) mRNAs and cognate miRNA precursors, whereas the SAM (zeige TTN Antikörper) domain loads a silencing complex with AGO2 (zeige EIF2C2 Antikörper). AC6 (zeige ADCY6 Antikörper) and PKIa (zeige PKIA Antikörper) protein levels increase in cystic Bicc1-/- mouse kidneys.

  5. lack of Bicc1 leads to disruption of normal cell-cell junctions.

  6. Data suggest that Bicc1 functions by modulating the expression of polycystin 2 (Pkd2 (zeige PKD2 Antikörper) by antagonizing the repressive activity of the miR-17 microRNA family on the 3'UTR (zeige UTS2R Antikörper) of Pkd2 (zeige PKD2 Antikörper) mRNA.

  7. Binds homoribopolymers in vitro; the third K homology domain is necessary and sufficient for in vitro Bicc1 RNA binding.

  8. Bicc1 and SamCystin (zeige ANKS6 Antikörper) interact at the protein level suggesting that they function in a common molecular pathway that when perturbed, is involved in cystogenesis.

  9. Data report that targeted inactivation of BicC randomizes left-right asymmetry by disrupting the planar alignment of motile cilia required for cilia-driven fluid flow, and that BicC can uncouple Dvl2 (zeige DVL2 Antikörper) signaling from the canonical Wnt (zeige WNT2 Antikörper) pathway.

BICC1 Antigen-Profil

Protein Überblick

This gene encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product.

Genbezeichner und Symbole assoziert mit BICC1

  • BicC family RNA binding protein 1 (BICC1) Antikörper
  • BicC family RNA binding protein 1b (bicc1b) Antikörper
  • BicC family RNA binding protein 1 (bicc1) Antikörper
  • BicC family RNA binding protein 1 (Bicc1) Antikörper
  • Bic-C Antikörper
  • Bicaudal-C Antikörper
  • BICC Antikörper
  • bicc1 Antikörper
  • bpk Antikörper
  • CYSRD Antikörper
  • jcpk Antikörper
  • x-Bic-C Antikörper
  • xBic-C Antikörper

Bezeichner auf Proteinebene für BICC1

bicaudal C homolog 1 (Drosophila) , bicaudal C homolog 1-like , bicaudal C homolog 1 , protein bicaudal C homolog 1-like , bic-C , protein bicaudal C homolog 1 , juvenile congenital polycystic kidney disease , polycystic kidney mutation of BALB/c origin

GENE ID SPEZIES
423604 Gallus gallus
450473 Pan troglodytes
537799 Bos taurus
571411 Danio rerio
733856 Xenopus (Silurana) tropicalis
701228 Macaca mulatta
100013824 Monodelphis domestica
100072191 Equus caballus
100412529 Callithrix jacchus
100466363 Ailuropoda melanoleuca
100589900 Nomascus leucogenys
80114 Homo sapiens
608626 Canis lupus familiaris
83675 Mus musculus
361832 Rattus norvegicus
100154253 Sus scrofa
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