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BACE1 Proteine

(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].

23 Treffer

BACE1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7273905
 
BACE1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7273904
 
BACE1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7273906
 
BACE1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Produktnummer ABIN7121998
 
BACE1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Produktnummer ABIN1346345
 
BACE1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Produktnummer ABIN7320444
 
BACE1 Spezies: Human Wirt: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE.
Pubmed 2 Referenzen
Produktnummer ABIN2180626
 
BACE1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505103
 
BACE1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Produktnummer ABIN7391801
 
BACE1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Produktnummer ABIN7411204
 
BACE1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7575117
 
BACE1 Spezies: Human Wirt: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Produktnummer ABIN7607491
 
BACE1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Produktnummer ABIN7391804
 
BACE1 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Produktnummer ABIN7391807
 
BACE1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7318053
 
BACE1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7318054
 
BACE1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7318055
 
BACE1 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
Produktnummer ABIN7596290
 
BACE1 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Produktnummer ABIN3008460
 
BACE1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715129
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Enzyme Activity Assay (EAA)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Cow
    • Guinea Pig
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Yeast
    • Baculovirus infected Insect Cells
    • Mammalian Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 22-457
    • AA 170-428
    • AA 181-366
    • AA 190-430
    • AA 22-429
    • AA 22-460
    • AA 22-501
    • AA 46-152
    • Transcript Variant A
  • Konjugat
    • His tag
    • Unkonjugiert
    • Fc Tag
    • His tag,GST tag
    • GST tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Hersteller
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • Abbexa
    • OriGene

Aktuelle Publikationen für unsere BACE1 Proteine

Mycroft-West, Devlin, Cooper, Procter, Miller, Fernig, Guerrini, Guimond, Lima, Yates, Skidmore: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." in: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).

Peters-Libeu, Campagna, Mitsumori, Poksay, Spilman, Sabogal, Bredesen, John: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." in: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).

Aliase für BACE1 Proteine

beta-secretase 1 (BACE1) Proteine
beta-site APP cleaving enzyme 1 (Bace1) Proteine
beta-secretase 1 (Bace1) Proteine
beta-site APP-cleaving enzyme 1 (bace1) Proteine
ASP2 Proteine
BACE Proteine
Bace Proteine
BACE1 Proteine
C76936 Proteine
HSPC104 Proteine
MGC145931 Proteine
zgc:77409 Proteine
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