BACE1 Proteine
(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
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BACE1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
BACE1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
BACE1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
BACE1
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
BACE1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
BACE1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 97 % as determined by SDS-PAGE
Active
1 image
BACE1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>98 % as determined by SDS-PAGE.
1 image
2 Referenzen
BACE1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
BACE1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
BACE1
Spezies: Human
Wirt: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
BACE1
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
BACE1
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
BACE1
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS, EAA
Active
BACE1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
BACE1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
BACE1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Active
BACE1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
BACE1
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
BACE1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
BACE1
Spezies: Meerschweinchen
Wirt: Hefe
Recombinant
> 90 %
ELISA
Aktuelle Publikationen für unsere BACE1 Proteine
: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." in: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." in: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).
Aliase für BACE1 Proteine
beta-secretase 1 (BACE1) Proteinebeta-site APP cleaving enzyme 1 (Bace1) Proteine
beta-secretase 1 (Bace1) Proteine
beta-site APP-cleaving enzyme 1 (bace1) Proteine
ASP2 Proteine
BACE Proteine
Bace Proteine
BACE1 Proteine
C76936 Proteine
HSPC104 Proteine
MGC145931 Proteine
zgc:77409 Proteine
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- Baculoviral IAP Repeat-Containing 5 Proteine
- Baculoviral IAP Repeat-Containing 7 Proteine
- BAD Proteine
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- BAG1 Proteine
- BAG2 Proteine
- BAG3 Proteine
- BAG4 Proteine
- BAG5 Proteine
- BAHD1 Proteine
- BAI1 Proteine
- BAI1-Associated Protein 2-Like-1 Proteine
- BAI2 Proteine
- BAI3 Proteine
- BAIAP2 Proteine
- BAIAP2L2 Proteine
- BAIAP3 Proteine
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