anti-Basigin (Ok Blood Group) (BSG) Antikörper

The protein encoded by BSG is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Zusätzlich bieten wir Ihnen CD147 Kits (68) und CD147 Proteine (38) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BSG 682 P35613
BSG 12215 P18572
BSG 25246 P26453
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Top anti-CD147 Antikörper auf antikoerper-online.de

Showing 10 out of 531 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Maus Unkonjugiert FACS, IHC (p)   0.1 mg 6 bis 8 Tage
$269.50
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of CD147/Emmprin using anti-CD147/Emmprin antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human placenta tissue lysates,  Lane 2: JURKAT whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-CD147/Emmprin antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CD147/Emmprin at approximately 55KD. The expected band size for CD147/Emmprin is at 42KD. IHC analysis of CD147/Emmprin using anti-CD147/Emmprin antibody . CD147/Emmprin was detected in paraffin-embedded section of human lung cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-CD147/Emmprin Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert WB Anti-CD147 antibody, Western blotting WB: Human Fibroma Cell Lysate 100 μg 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert FACS, WB Anti- CD147 Picoband antibody, Western blotting All lanes: Anti CD147  at 0.5ug/ml Lane 1: Human Placenta Tissue Lysate at 50ug Lane 2: JURKAT Whole Cell Lysate at 40ug Lane 3: U20S Whole Cell Lysate at 40ug Predicted bind size: 42KD Observed bind size: 42KD Anti- CD147 Picoband antibody, Western blotting All lanes: Anti CD147  at 0.5ug/ml WB: Recombinant Human CD147 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg 4 bis 6 Tage
$280.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-BSG Antibody Titration: 0.125 ug/ml Positive Control: 721_B Whole Cell 100 μL 2 bis 3 Tage
$289.00
Details
Hund Kaninchen Unkonjugiert WB WB Suggested Anti-BSG Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-BSG  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert FACS, IF, IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$522.50
Details
Human Maus Unkonjugiert IF, IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$522.50
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of CD147 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CD147 expression in A431 (A), HeLa (B), Raw264.7 (C), mouse heart (D) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Maus FITC FACS, IHC (p), IP, WB Surface staining of human peripheral blood with anti-human CD147 (MEM-M6/1) FITC. 100 Tests 5 bis 7 Tage
$428.84
Details

Am meisten referenzierte anti-CD147 Antikörper

  1. Human Monoclonal CD147 Primary Antibody für FACS - ABIN5500581 : Choi, Yu, Smuga-Otto, Salvagiotto, Rehrauer, Vodyanik, Thomson, Slukvin: Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. in Stem cells (Dayton, Ohio) 2009 (PubMed)
    Show all 9 Pubmed References

  2. Rat (Rattus) Monoclonal CD147 Primary Antibody für CyTOF, FACS - ABIN4889984 : Fossum, Mallett, Barclay: The MRC OX-47 antigen is a member of the immunoglobulin superfamily with an unusual transmembrane sequence. in European journal of immunology 1991 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal CD147 Primary Antibody für FACS, IP - ABIN533486 : Tang, Nakada, Rafferty, Laraio, McCabe, Millar, Cunningham, Snyder, Bugelski, Yan: Regulation of vascular endothelial growth factor expression by EMMPRIN via the PI3K-Akt signaling pathway. in Molecular cancer research : MCR 2006 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal CD147 Primary Antibody für CyTOF, FACS - ABIN5500590 : Lathia, Gallagher, Myers, Li, Vasanji, McLendon, Hjelmeland, Huang, Rich: Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. in PLoS ONE 2011 (PubMed)
    Show all 5 Pubmed References

  5. Mouse (Murine) Polyclonal CD147 Primary Antibody für CyTOF, FACS - ABIN4899651 : Ramo, Cashman, Kumar-Singh: Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE. in Investigative ophthalmology & visual science 2008 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal CD147 Primary Antibody für FACS, IHC (p) - ABIN238486 : Xu, Hemler: Metabolic activation-related CD147-CD98 complex. in Molecular & cellular proteomics : MCP 2005 (PubMed)
    Show all 11 Pubmed References

  7. Human Monoclonal CD147 Primary Antibody für BI, IHC (fro) - ABIN2689942 : Olivier, Rybicki, Bouhassira: Differentiation of human embryonic stem cells into bipotent mesenchymal stem cells. in Stem cells (Dayton, Ohio) 2006 (PubMed)
    Show all 4 Pubmed References

  8. Human Monoclonal CD147 Primary Antibody für FACS, IHC (p) - ABIN535271 : Schmidt, Bültmann, Fischel, Gillitzer, Cullen, Walch, Jost, Ungerer, Tolley, Lindemann, Gawaz, Schömig, May: Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes. in Circulation research 2008 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal CD147 Primary Antibody für FACS, WB - ABIN3043762 : Lu, Lv, Kim, Ha, Kim: Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma. in Oncology letters 2012 (PubMed)
    Show all 3 Pubmed References

  10. Human Polyclonal CD147 Primary Antibody für WB - ABIN3043170 : Zhang, Yang, Liu, Liu, Teng, Zhang, Yin, Liu et al.: iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of ... in Oncology letters 2017 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen CD147 Interaktionspartner

Cow (Bovine) Basigin (Ok Blood Group) (BSG) Interaktionspartner

  1. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2; MMP-14) in endometrial stromal cells; progesterone-rich conditions stimulate expression of EMMPRIN in endometrium.

  2. The selective S-nitrosylation of EMMPRIN and GOLPH3 at the Golgi apparatus in endothelial cells results from the physical proximity to eNOS-derived nitric oxide.

Human Basigin (Ok Blood Group) (BSG) Interaktionspartner

  1. Lewis y antigen and CD147 were significantly upregulated in ovarian tumors.

  2. Overexpression of CD147 impaired the interaction between CAS and E-cad and triggered the release of beta catenin from the CAS/E-cad/beta catenin complex, which in turn led to Epithelial-to-Mesenchymal Transition and endometrial adenocarcinoma.

  3. Study verified the target action association between TCSF and miR146a5p with high throughput data analysis and experimental results in nonsmall cell lung cancer (NSCLC). Protein level of TCSF in cancerous lung tissues was upregulated in NSCLC tissues. In vitro experiment in A549 cell line revealed that miR-146a-5p had a role in cell viability, proliferation and apoptosis by regulating the target gene TCSF.

  4. Higher CD147 expression was found in EGFR-TKI-sensitive non-small cell lung cancer (NSCLC) cell lines than in relatively resistant NSCLC cell lines.

  5. In lung specimens, CD147 and MUC5AC expression levels were increased in chronic obstructive pulmonary disease patients. Increased CD147 levels induced by cigarette smoke extract could stimulate MUC5AC secretion through the MMP9 and p38 MAPK signaling pathway in human bronchial epithelial cells.

  6. This study analyzed the direct interaction between CAIV and the two Monocarboxylate transporters (MCTs) chaperones basigin (CD147) and embigin (GP70). In human CD147, binding of CAIV was mediated by the negatively charged Glu-73.

  7. Plasma CyP A and CD147 can serve as indicators of renal disease progression in type 2 diabetes patients

  8. PKM2 and other key regulators of Warburg effect positively correlate with CD147 (EMMPRIN) gene expression and predict survival in multiple myeloma.

  9. In periodontitis, EMMPRIN regulates MMP-2, 9 expressions, the activation of Wnt/beta-catenin signaling pathway downregulates the EMMPRIN/MMP-2, 9 routes and the blockade of EMMPRIN attenuates Wnt/beta-catenin signaling pathway.

  10. Overexpression of EMMPRIN was associated with lymphatic metastasis and advanced stage of non-small cell lung cancer

  11. Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion by Plasmodium falciparum.

  12. Results demonstrated that CD147 serves a key role in melanoma cell apoptosis, which may be mediated via IGFBP2 and the PTEN/PI3K/AKT signaling pathway. In addition, the expression of IGFBP2 and CD147 was upregulated and exhibited a positive association in melanoma clinical tissues.

  13. findings suggest that the OK/BSG expression levels on RBCs might be related to P. falciparum invasion

  14. Silencing of CD147 in endothelial cells inhibited Human cytomegalovirus entry but not entry into fibroblasts.

  15. ectopic CD147-polarized distribution on basolateral membrane promotes hepatocyte depolarization by activation of the CD147-integrin alpha5beta1-E-cadherin ubiquitination-partitioning defective 3 decrease and beta-catenin translocation signaling cascade, replenishing a molecular pathway in hepatic carcinogenesis

  16. CD147 and the beta2-adrenergic receptor form hetero-oligomeric complexes.Actinin-4 directly binds to the cytosolic tail of CD147 and governs the assembly of CD147-beta2-adrenergic receptor complexes in highly ordered clusters at bacterial adhesion sites.

  17. Plasma sCD147 levels are elevated in breast cancer patients. Soluble CD147 is also associated with tumour size, lymph node metastasis, high recurrent risk, and chemoresistance.

  18. overexpression of CD147 may promote OSF progression.

  19. these findings show that CD147 is a novel and key mediator of IL-22-induced psoriatic alterations in the epidermis and might be a therapeutic target in patients with psoriasis.

  20. Data indicate that CD147 promotes breast cancer cell proliferation, metastasis, and invasion by modulating matrix metalloproteinase 9 (MMP-9) and vascular endothelial growth factor (VEGF) expression.

Mouse (Murine) Basigin (Ok Blood Group) (BSG) Interaktionspartner

  1. The present study reveals the positive correlation of CypA/CD147 signaling and osteoclast-related MMP-9 expression in mice inflammatory periapical lesions progression. Therefore, intervention of CypA/CD147 signaling could probably provide a potential therapeutic target for attenuating inflammatory bone resorption.

  2. the feedback loop of the "EMMPRIN/NF-kappaB" pathway plays an important role in atherosclerotic plaques via modulation of autophagy in macrophages.

  3. The fibroblast-specific deletion of Basigin did not influence the growth, fertility and the general condition of the mice. No obvious differences were found in the size, morphology, and histological structure of the major organs, including heart, liver, spleen, lung and kidney, between the knockout mice and the control mice. The deletion of Basigin in fibroblasts did not induce apoptosis in the tissues of the major organs

  4. ectopic CD147-polarized distribution on basolateral membrane promotes hepatocyte depolarization by activation of the CD147-integrin alpha5beta1-E-cadherin ubiquitination-partitioning defective 3 decrease and beta-catenin translocation signaling cascade, replenishing a molecular pathway in hepatic carcinogenesis

  5. CD147 deletion in hepatic stellate cells alleviated CCl4-induced liver fibrosis and inhibited HSCs activation. Overexpression of CD147 upregulated the secretion of CXCL1.

  6. A new molecular mechanism for high angiogenic capacity, whereby microglia cells release basigin via up-regulation of PI3K-AKT and IGF-1 pathway to induce angiogenesis is unveiled.

  7. EMMPRIN inhibited bFGF-induced IL-6 secretion by reducing the p65 subunit phosphorylation, it might be concluded that bFGF and EMMPRIN crosstalk in their respective signaling pathways.

  8. protein-protein interaction studies on TRAF6 and BSG to get molecular level insights of the reactions.

  9. This study has highlighted basigin as a common essential molecule for various stimuli-induced impairment of retinal vascular barrier, which can be a target for strategies to establish a curative treatment of diabetic retinopathy

  10. Deletion of N-linked glycosylation at Asn152 on CD147 significantly suppressed in situ tumor metastasis in hepatocellular carcinoma.

  11. MCT1 and Basigin variant-2, but not Basigin variant-1, are expressed within the mouse pineal gland.

  12. this study provided a new mechanistic concept that CD147 can be a target for lymphocyte lineage reprogramming.

  13. these results suggested that CD147 plays a key role in reducing extrinsic apoptosis in spermatocytes, but not spermatogonia, through modulating NFkappaB signaling pathway.

  14. results establish neuroplastin and basigin as obligatory auxiliary subunits of native Plasma Membrane Calcium Atpases and key regulators of intracellular Ca2+ concentration.

  15. Data show that caveolin-3 binds to low glycosylated extracellular matrix metalloproteinase inducer (LG-EMMPRIN) in cardiac cells and in the hearts of healthy mice.

  16. These results suggest that basigin has a functional role as a binding partner with MCT2 in testicular and epididymal spermatozoa.

  17. both caveolin-1 and EMMPRIN mRNA levels increased gradually with progression of developmental stages, and peaked at day two postnatal. The current finding suggests that both caveolin-1 and EMMPRIN take part in mouse tooth development, especially in the differentiation and organization of odontogenic tissues.

  18. knockdown of CD147 on Hepa1-6 cells resulted in significantly increased T cells chemotaxis induced by CypA both in vivo and in vitro.

  19. These findings indicate that TGF-beta1-CD147 loop plays a key role in regulating the HSC activation and combination of TGF-beta receptor inhibitor and anti-CD147 antibody might be promised to reverse fibrogenesis.

  20. Decreased CD147 expression inhibited osteoclast formation and bone resorption, inhibited RANKL-induced nuclear translocation of the nuclear factor of activated T cells NFATc1.

Rabbit Basigin (Ok Blood Group) (BSG) Interaktionspartner

  1. CD147 is required for the expression of MCT1 and MCT4 in the corneal endothelium. Silencing CD147 slows lactate efflux, resulting in stromal lactate accumulation and corneal edema.

CD147 (BSG) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit BSG

  • basigin (Ok blood group) (BSG) Antikörper
  • basigin (Bsg) Antikörper
  • basigin (Ok blood group) (Bsg) Antikörper
  • basigin (bsg) Antikörper
  • basigin (Ok blood group) S homeolog (bsg.S) Antikörper
  • 5A11 Antikörper
  • 5F7 Antikörper
  • AI115436 Antikörper
  • AI325119 Antikörper
  • basignin Antikörper
  • bsg Antikörper
  • CD147 Antikörper
  • CE9 Antikörper
  • EMMPRIN Antikörper
  • HT-7 Antikörper
  • HT7 Antikörper
  • M6 Antikörper
  • OK Antikörper
  • Ox47R Antikörper
  • prso03 Antikörper
  • RPE7 Antikörper
  • TCSF Antikörper
  • wu:fb26a05 Antikörper
  • wu:fo98e12 Antikörper

Bezeichner auf Proteinebene für BSG

basigin , CD147 antigen , OK blood group antigen , collagenase stimulatory factor , extracellular matrix metalloproteinase inducer , leukocyte activation antigen M6 , tumor cell-derived collagenase stimulatory factor , 5A11/Basigin , HT7 antigen , basic immunoglobulin superfamily , gp 42 , membrane glycoprotein gp42 , neurothelin , gp42/basigin/OX-47/HT7 , Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian) , Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian) , OX-47 antigen , glycoprotein CE9 , 5A11 antigen , blood-brain barrier HT7 antigen , 5A11/Basigin-2 , cd147 , basigin (Ok blood group) S homeolog

GENE ID SPEZIES
508716 Bos taurus
682 Homo sapiens
12215 Mus musculus
100009229 Oryctolagus cuniculus
100141312 Sus scrofa
25246 Rattus norvegicus
770363 Gallus gallus
476758 Canis lupus familiaris
100720467 Cavia porcellus
337692 Danio rerio
100689246 Cricetulus griseus
734661 Xenopus laevis
Ausgewählte Anbieter für anti-CD147 (BSG) Antikörper
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