anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 2 (BACH2) Antikörper

Transcriptional regulator that acts as repressor or activator. Zusätzlich bieten wir Ihnen BACH2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BACH2 12014  
BACH2 313125  
BACH2 60468 Q9BYV9
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Top anti-BACH2 Antikörper auf antikoerper-online.de

Showing 10 out of 64 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-BACH2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Thymus 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-BACH2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  293T cell lysate BACH2 is supported by BioGPS gene expression data to be expressed in HEK293T Human Tonsil 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert FACS, WB BACH2 Antibody (C-term)  western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the BACH2 antibody detected the BACH2 protein (arrow). BACH2 Antibody (C-term)  flow cytometric analysis of  MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert EIA, WB BACH2 Antibody (Center) western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the BACH2 antibody detected the BACH2 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, FACS, WB BACH2 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. BACH2 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the BACH2 antibody detected the BACH2 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Human Spleen (formalin-fixed, paraffin-embedded) stained with BACH2 antibody ABIN462219 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Tonsil (formalin-fixed, paraffin-embedded) stained with BACH2 antibody ABIN462219 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details
Maus Kaninchen Unkonjugiert IP, ELISA, WB Western Blot of Rabbit anti-Bach2 antibody. Lane 1: 293T cell lysates overexpressing Bach2-Flag. Lane 2: 293T cell lysates. Load: 20 µg per lane. Primary antibody: Bach-2 antibody at 1:1000 for overnight at 4°C. Secondary antibody: rabbit HRP secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted (native)/Observed (over-expressed) size: 91.7 kDa, ~130 kDa for Bach2. Other band(s): none. 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$389.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: BACH2 Antibody [NBP2-14345] - Staining of human lymph node shows strong cytoplasmic positivity in germinal center cells. Western Blot: BACH2 Antibody [NBP2-14345] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Anti-BACH2 antibody IHC staining of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1100167 concentration 10 ug/ml. Anti-BACH2 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details

BACH2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,


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Rat (Rattus) ,


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Weitere Antikörper gegen BACH2 Interaktionspartner

Mouse (Murine) BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 2 (BACH2) Interaktionspartner

  1. Bach2 interacts with Batf family transcription factors and controls Th2 cell development via binding to the regulatory regions in the Th2 cytokine, Batf and Batf3 (zeige BATF3 Antikörper) gene loci.

  2. The study demonstrates that Bach2 is a direct repressor of the interleukin-2 (zeige IL2 Antikörper) gene in CD4 (zeige CD4 Antikörper) T cells during the immediate early (zeige JUN Antikörper) phase of AP-driven activation, thereby playing an important role in the maintenance of immune quiescence in the steady state

  3. Results suggest that the mTOR (zeige FRAP1 Antikörper)-Bach2 cascade regulates proper cell cycle arrest in B cells as well as immunoglobulin gene rearrangement.

  4. The Bach2-C/EBPbeta (zeige CEBPB Antikörper) gene regulatory network pathway tunes multipotent progenitor commitment to myeloid and lymphoid lineages both under normal conditions and after infection.

  5. Data (including data from studies using transgenic/knockout mice) suggest that hyperactivated T-lymphocytes induce specific gene expression patterns in alveolar macrophages and dendritic cells; pulmonary alveolar proteinosis phenotype of Bach2-deficient mice is due to Bach2 deficiency in at least two types of immune cells, alveolar macrophages and dendritic cells.

  6. Data show that B-cell tumour suppressor BTB and CNC homology 2 (Bach2) was significantly downregulated by the loss of NF-kappaB (zeige NFKB1 Antikörper) subunit proto-oncogene (zeige RAB1A Antikörper) protein c (zeige PROC Antikörper)-rel (c-Rel (zeige NFkBP65 Antikörper)) .

  7. In this study silencing BACH2 in mantle cell lymphoma cells resulted in increased proliferation and enhanced tumor dispersal in hypoxic microenvironments, suggesting a tumor suppressor-like role of BACH2.

  8. this study shows that the transcription factor BACH2 promotes memory CD8 (zeige CD8A Antikörper)+ T cell generation by blocking access to genomic regulatory sites recognized by AP-1 (zeige JUN Antikörper)

  9. this study shows that B cells of lower affinity receive weaker T cell help, which results in higher expression of the transcriptional repressor Bach2 and promotes the development of memory B cells

  10. Bach2 controls homeostasis of eosinophils via restricting the production of Il-5 (zeige IL5 Antikörper) in CD4 (zeige CD4 Antikörper)(+) T cells.

Human BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 2 (BACH2) Interaktionspartner

  1. The epithelial-mesenchymal transition (EMT (zeige ITK Antikörper)) pathway was also influenced by miR (zeige MLXIP Antikörper)-130a-3p down-regulation. In conclusion, miR (zeige MLXIP Antikörper)-130a-3p could bind to BACH2, inhibit nasopharyngeal carcinoma cell abilities, and promote cell apoptosis.

  2. Ikaros (zeige IKZF1 Antikörper) regulates expression of the BCL6 (zeige BCL6 Antikörper)/BACH2 axis in acute lymphoblastic leukemia cells.

  3. Data show that BACH2 and STAT5B (zeige STAT5B Antikörper) are activated by viral insertions, generating chimeric mRNAs specifically enriched in T regulatory cells favoring their persistence.

  4. BACH2 downregulation contributes to constitutive activation of the nuclear factor-kappaB.

  5. BACH2 haploinsufficiency causing a syndrome of immune deficiency and autoimmunity is described in two families. Affected subjects had lymphocyte-maturation defects that caused immunoglobulin deficiency and intestinal inflammation.

  6. In this study silencing BACH2 in mantle cell lymphoma cells resulted in increased proliferation and enhanced tumor dispersal in hypoxic microenvironments, suggesting a tumor suppressor-like role of BACH2.

  7. we developed a CRISPR-Cas9-based tool for specific DNA methylation (zeige HELLS Antikörper) consisting of deactivated Cas9 (dCas9) nuclease (zeige DCLRE1C Antikörper) and catalytic domain of the DNA methyltransferase (zeige DNMT1 Antikörper) DNMT3A (zeige DNMT3A Antikörper) targeted by co-expression of a guide RNA to any 20 bp DNA sequence followed by the NGG trinucleotide.we demonstrated that directed DNA methylation (zeige HELLS Antikörper) of a wider promoter region of the target loci IL6ST (zeige IL6ST Antikörper) and BACH2 decreased their expression

  8. genetic association studies in population in the United Kingdom: Data suggest that an SNP in BACH2 (rs3757247) is associated with autoimmune Addison's disease and with polyglandular autoimmune syndrome type 2. These findings were replicated in a Norwegian validation cohort.

  9. The shift in the CSDs by heme binding suggested that heme binding causes Bach2(331-520) to adopt a more compact conformation. In addition, heme binding to the CP-motif could reduce the flexibility of Bach2(331-520) Consequently, the five-coordinated heme binding destabilizes Bach2(331-520), by reducing the flexibility of the polypeptide chain.

  10. The study identifies a strong association of Coeliac Disease with a network of BACH2 regulated genes, supporting emerging evidence of an important role of BACH2 in the regulation of T cell differentiation and prevention of autoimmune disease.

BACH2 Antigen-Profil

Protein Überblick

Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK (By similarity).

Genbezeichner und Symbole assoziert mit BACH2

  • BTB and CNC homology, basic leucine zipper transcription factor 2 (Bach2) Antikörper
  • BTB domain and CNC homolog 2 (Bach2) Antikörper
  • BTB domain and CNC homolog 2 (BACH2) Antikörper
  • BTB and CNC homology 1, basic leucine zipper transcription factor 2b (bach2b) Antikörper
  • BTB domain and CNC homolog 2 (bach2) Antikörper
  • bach2 Antikörper
  • BTBD25 Antikörper
  • E030004N02Rik Antikörper
  • si:dkeyp-4f12.1 Antikörper
  • si:dkeyp-4f12.2 Antikörper

Bezeichner auf Proteinebene für BACH2

BTB and CNC homolog 2 , Transcription regulator protein BACH2 (BTB and CNC homolog 2) , transcription regulator protein BACH2 , BTB and CNC homology 2 , BTB and CNC homology 1, basic leucine zipper transcription factor 2 , transcription regulator protein BACH2-like

GENE ID SPEZIES
12014 Mus musculus
313125 Rattus norvegicus
60468 Homo sapiens
421809 Gallus gallus
481923 Canis lupus familiaris
538296 Bos taurus
555350 Danio rerio
702740 Macaca mulatta
100065814 Equus caballus
100218595 Taeniopygia guttata
100351257 Oryctolagus cuniculus
100402816 Callithrix jacchus
100447938 Pongo abelii
100467178 Ailuropoda melanoleuca
100485849 Xenopus (Silurana) tropicalis
100025933 Monodelphis domestica
100554926 Anolis carolinensis
100595920 Nomascus leucogenys
100717541 Cavia porcellus
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