BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) ELISA Kits

BACH1 encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). Zusätzlich bieten wir Ihnen BACH1 Antikörper (113) und BACH1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus BACH1 BACH1 12013 P97302
BACH1 571 O14867
Anti-Ratte BACH1 BACH1 304127  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Human 9.375 pg/mL 37.5-2400 pg/mL Typical standard curve 96 Tests 15 bis 18 Tage
$910.56
Details

Weitere ELISA Kits für BACH1 Interaktionspartner

Zebrafish BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) Interaktionspartner

  1. Bach1 regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 inhibition based on its level in each tissue.

  2. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

Mouse (Murine) BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) Interaktionspartner

  1. we can conclude that miR-27a-5p is relevant to liver Ischemia-reperfusion (I/R) injury and overexpression of miR-27a-5p may alleviate apoptosis in hypoxia/reoxygenation injury by targeting Bach1 in vitro.

  2. Bach1 inhibition alleviates oxidative-stress-induced osteoblast apoptosis and dysfunction by enhancing Nrf2/ARE signaling activation, findings that suggest a critical role for the Bach1/Nrf2/ARE regulation axis in osteoporosis progression.

  3. heme binding to the intrinsically disordered region of Bach1

  4. disordered-ordered transition such as "coupled folding and binding" is not involved in the Bach1-heme system.

  5. Decreasing malondialdehyde levels via nuclear factor (erythroidderived 2)like 2 protein/BTB and CNC homology 1 mediated antioxidant effect.

  6. overexpression of miR-98-5p inhibited Bach1 expression while suppression of miR-98-5p promoted Bach1 expression in neurons.

  7. Anemia of inflammation and myelodysplastic syndrome might involve reduced activity of Bach 1 and Bach2.

  8. Theraputic effects of Pirfenidone for induced pulmonary fibrosis were involved in Nrf2/Bach1 equilibrium which regulated the capacity of oxidative stress.

  9. Data suggest that Abcb10 silencing results in alteration in heme biosynthesis transcriptional profile due to repression by transcriptional regulator Bach1. (Abcb10 = ATP-binding cassette, sub-family B [MDR-TAP], member 10; Bach1 = BTB and CNC homology 1, basic leucine zipper transcription factor 1)

  10. This study showed that RANKL favors osteoclastogenesis via attenuation of Nrf2-mediated antioxidant enzyme expression by competing with Bach1 nuclear accumulation.

  11. this study provides new insight into the function of iron and Bach1 in erythroblast maturation by using efficacious regimens that can induce severe ID.

  12. miR-196a, which binds to the 3'-untranslated region of the transcriptional repressor BTB and CNC homology 1 (Bach1) and regulates its expression, and subsequently leads to higher levels of lung HO-1 mRNA.

  13. Bach1 siRNA exerts protective effects against bleomycin-induced pulmonary fibrosis in mice.

  14. These results suggest that Bach1 and Bach2 work in a complementary manner to maintain the normal function of the AMs and surfactant homeostasis in the lung.

  15. By integrating the chromatin immunoprecipitation and next-generation sequencing data with a comparative analysis of gene expression in Bach1-deficient and wild type immortalized mouse embryonic fibroblasts (iMEFs), study found 35 new genes whose expression was repressed by BACH1. Known functions of some of these genes suggested a role of BACH1 in adipocyte differentiation, which was verified using iMEFs.

  16. Bach1 deficiency reduces the severity of osteoarthritis-like changes. This may be due to maintenance of cartilage homeostasis and joint health by antioxidant effects

  17. Bach1 suppresses angiogenesis after ischemic injury and impairs Wnt/beta-catenin signaling by disrupting the interaction between beta-catenin and TCF4 and by recruiting histone deacetylase 1 to the promoter of TCF4-targeted genes.

  18. Bach1 deficiency and accompanying overexpression of HO-1 did not influence aging or p53 deficiency-driven tumorigenesis.

  19. Our results suggest that Bach2 functions with Bach1 and EBF1 to promote B cell development by repressing myeloid genes in common lymphoid progenitor cells

  20. HO-1 induction after ischemia was associated to down-regulation of transcriptional repressor Bach-1, and induction of HO-1 when HO enzymatic activity was inhibited was related to worst outcome after brain ischemia.

Human BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) Interaktionspartner

  1. results suggested that the IL-16 rs859, CYP19A1 rs4646, and BACH1 rs372883 polymorphisms have potential roles in the genetic susceptibility to IgAN in Chinese Han population.

  2. Study identified Bach1 as a key regulator that controls multiple factors essential for epithelial ovarian cancer (EOC) metastasis and growth. Bach1 promotes EMT gene expression by recruiting HMGA2 in EOC cells to promote EMT and ovarian cancer metastasis.

  3. BACH1 gene expression inversely correlates with electron transport chain gene expression in tumours from patients with breast cancer and in other tumour types; mitochondrial metabolism can be exploited by targeting BACH1 to sensitize breast cancer and potentially other tumour tissues to mitochondrial inhibitors

  4. The authors found substantially lower BACH1 expression in PDAC compared with normal pancreatic tissues and the rs372883T allele had significantly lower BACH1 levels than the rs372883C allele in both tumor and normal tissues.

  5. This is the first study to explore the relationship between tagSNPs of BACH1 and ATDH in a Chinese cohort. Based on this cohort, genetic polymorphisms of BACH1 may be associated with susceptibility to ATDH in the Chinese population.

  6. Nfr2 and Bach1 expression are altered in colorectal carcinoma but in different ways

  7. Anemia of inflammation and myelodysplastic syndrome might involve reduced activity of Bach 1 and Bach2

  8. In conclusion, these findings highlight the central role of Bach1 in HO-1-dependent neuronal response to oxidative stress.

  9. BACH1 performs stabilization of mitotic spindle orientation together with HMMR and CRM1 in mitosis, and that the cell cycle-specific phosphorylation switches the transcriptional and mitotic functions of BACH1.

  10. BACH1 is overexpressed in prostate cancer

  11. BACH1 may inhibit the progression of colorectal cancer through BACH1/CXCR4 pathway.

  12. BACH1 overexpression impaired the association between p53 and SP1 via competitive binding p53, and antagonized the impact of p53 on MGMT expression.

  13. In light of a pivotal role of NRF2 and BACH1 in response to oxidative stress and regulation of HO-1, we examined if smoke-induced HO-1 expression is modulated through the NRF2/BACH1 axis. We demonstrated that smoke causes significant nuclear translocation of NRF2, but only a slight decrease in nuclear BACH1.

  14. these findings suggested that increased miR-155 expression in activated monocytes leads to enhanced phagocytic activity via BACH-1 regulation in beta-thalassemia/HbE.

  15. The electrophilic character of quinones ensure their conjugation with Bach1, which is important for the downregulation of Bach1 and the upregulation of Nrf2 signaling.

  16. Our results suggest that the bach1-specific small interfering RNA effectively decrease CXCR4 receptor, matrix metalloproteinase-9 expression and breast adenocarcinoma cells invasive, also increased the expression of tumor-suppressive microRNA-203 and miR-145

  17. BACH1 down-regulation in HT29 colon cancer cells had no effect on cell growth but did inhibit cell migration by decreasing metastasis-related genes expression.

  18. This study indicates that the expression of BACH1 could be elevated as a compensatory mechanism to decrease the globin chain imbalance as well as to reduce the oxidative stress found in hemoglobin E/beta-thalassemia.

  19. A short while ago some studies suggested that BACH1 is involved in cancers, especially breast cancer. This factor is mentioned as a novel master regulator which adjusts several genes involved in bone metastasis of breast cancer, especially CXCR4 and MMP1, two main genes in the enhancement of cancer cell migration and invasion to distant organs. [Review]

  20. Bach1 suppresses cell proliferation and induces cell-cycle arrest and apoptosis.

BACH1 Antigen-Profil

Beschreibung des Gens

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.

Genbezeichner und Symbole assoziert mit BACH1

  • BTB domain and CNC homolog 1 (BACH1) Antikörper
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 b (bach1b) Antikörper
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (bach1) Antikörper
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (Bach1) Antikörper
  • BTB domain and CNC homolog 1 (Bach1) Antikörper
  • 6230421P05Rik Antikörper
  • AI323795 Antikörper
  • BACH-1 Antikörper
  • BACH1 Antikörper
  • zgc:112205 Antikörper

Bezeichner auf Proteinebene für BACH1

BTB and CNC homology 1 transcription factor , BTB and CNC homology 1, basic leucine zipper transcription factor 1 , basic leucine zipper transcription factor 1 , transcription regulator protein BACH1-like , BTB and CNC homolog 1 , transcription regulator protein BACH1 , HA2303 , basic region leucine zipper transcriptional regulator BACH1

GENE ID SPEZIES
418488 Gallus gallus
487718 Canis lupus familiaris
531350 Bos taurus
100523514 Sus scrofa
553688 Danio rerio
705817 Macaca mulatta
745234 Pan troglodytes
100053654 Equus caballus
100125783 Xenopus (Silurana) tropicalis
100353797 Oryctolagus cuniculus
100385069 Callithrix jacchus
100448413 Pongo abelii
100464674 Ailuropoda melanoleuca
100549402 Meleagris gallopavo
100595281 Nomascus leucogenys
12013 Mus musculus
571 Homo sapiens
304127 Rattus norvegicus
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