anti-BCL2-Associated Athanogene 3 (BAG3) Antikörper

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. Zusätzlich bieten wir Ihnen BAG3 Kits (18) und BAG3 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BAG3 9531 O95817
BAG3 29810 Q9JLV1
BAG3 293524  
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Top anti-BAG3 Antikörper auf antikoerper-online.de

Showing 10 out of 142 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-BAG3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: HT1080 cell lysate BAG3 is supported by BioGPS gene expression data to be expressed in HT1080 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Human Ziege Unkonjugiert ELISA, IHC, WB Antibody (0.1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.62
Details
Human Ziege Unkonjugiert ELISA, IHC, WB ABIN1686794 (0.1 µg/mL) staining of Human Pancreas lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.62
Details
Human Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (fro), IHC (p), IP, SimWes, WB Simple Western: BAG3 Antibody [NBP2-27398] - Simple Western lane view shows a specific band for BAG3 in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Immunohistochemistry-Frozen: BAG3 Antibody [NBP2-27398] - Frozen mouse muscle tissue section stained for BAG-3 expression using NBP2-27398 at 1:2000. The tissue section was fixed in 3.8% paraformaldehyde prior to staining. BAG-3 localizes with Z-disk proteins. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of BAG3 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- Bag3 Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis of extracts from 293, using BAG3 (Phospho-Tyr457) Antibody. ABIN6271653 at 1/200 staining Human kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$450.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: BAG3 Antibody [NBP2-15543] - Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using antibody at 1:100 dilution. Western Blot: BAG3 Antibody [NBP2-15543] - BAG3 antibody detects BAG3 protein by Western blot analysis. A. 50 ug mouse heart lysate/extract 7. 5 % SDS-PAGEBAG3 antibody dilution: 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of BAG3 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with Western blot analysis of BAG3 expression in K562 (A), HEK293T (B), Hela (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details

Am meisten referenzierte anti-BAG3 Antikörper

  1. Human Polyclonal BAG3 Primary Antibody für ICC, IF - ABIN4282959 : Goldman, Chen, Roesly, Hill, Tome, Dvorak, Bernstein, Dvorak: Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis. in American journal of physiology. Gastrointestinal and liver physiology 2011 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal BAG3 Primary Antibody für ELISA, WB - ABIN564108 : Youn, Lee, Lim, Yoon, Lim, Jung, Yeum, Park, Youn, Lee, Lee, Ikawa, Okabe, Tsujimoto, Lee: Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus. in American journal of physiology. Endocrinology and metabolism 2008 (PubMed)

  3. Human Polyclonal BAG3 Primary Antibody für IHC, IHC (p) - ABIN4282955 : Nymoen, Hetland Falkenthal, Holth, Ow, Ivshina, Tropé, Kuznetsov, Staff, Davidson: Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma. in Gynecologic oncology 2015 (PubMed)

Weitere Antikörper gegen BAG3 Interaktionspartner

Zebrafish BCL2-Associated Athanogene 3 (BAG3) Interaktionspartner

  1. This study therefore identifies both BAG3 reduction and autophagy promotion as potential therapies for FLNC (zeige FLNC Antikörper)(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  2. findings showed that the P209L mutation causes BAG3 to aggregate; proposed that the gradual loss of available BAG3(wt) and BAG3(P209L) proteins results in insufficiency leading to myofibrillar disintegration

Human BCL2-Associated Athanogene 3 (BAG3) Interaktionspartner

  1. The HSF1-BAG3-Mcl-1 signal axis is critical for protection of mutant KRAS colon cancer cells from AUY922-induced apoptosis.

  2. The Hsp70 (zeige HSP70 Antikörper)-Bag3 complex therefore functions as an important signaling node that senses proteotoxicity and triggers multiple pathways that control cell physiology, including activation of protein aggregation.

  3. study revealed oncogenic roles of BAG3 in chondrosarcoma and provided mechanisms that the BAG3-modulated the expression of RUNX2 (zeige RUNX2 Antikörper) through upregulation of beta-catenin (zeige CTNNB1 Antikörper).

  4. BAG3 interacted with CXCR4 (zeige CXCR4 Antikörper) mRNA and promoted its expression via its coding and 3'-untranslational regions.

  5. HSPB2 (zeige HSPB2 Antikörper) competes with HSPB8 (zeige HSPB8 Antikörper) for binding to BAG3. In contrast, HSPB3 (zeige HSPB3 Antikörper) negatively regulates HSPB2 (zeige HSPB2 Antikörper) association with BAG3.

  6. Silencing of HSPB8 markedly decreased the mitotic levels of BAG3 in HeLa cells, supporting its crucial role in BAG3 mitotic functions. The results support a role for the HSPB8-BAG3 chaperone complex in quality control of actin-based structure dynamics that are put under high tension, notably during cell cytokinesis.

  7. Our findings suggest that high levels of BIS expression might confer stem-cell-like properties on cancer cells through STAT3 (zeige STAT3 Antikörper) stabilization

  8. modulation of proteostasis is a distinct biological function of sAPPalpha and does not require surface-bound holo-APP (zeige APP Antikörper).

  9. higher levels of BAG3 were observed in hypertensive patients compared to healthy controls, and even higher levels in hypertensive diabetic patients compared to healthy subjects.

  10. BAG3 directly stabilizes hexokinase 2 (zeige HK2 Antikörper) mRNA and promotes aerobic glycolysis in pancreatic cancer cells.

Mouse (Murine) BCL2-Associated Athanogene 3 (BAG3) Interaktionspartner

  1. Thus, BAG3 is critical for the protein turnover of small HSPs via activation of autophagy in the heart.

  2. BAG3 plays a relevant role in regulating SNCA clearance via macroautophagy, and the heat shock protein 70 (zeige HSP70 Antikörper)-BAG3-sequestosome 1 (zeige SQSTM1 Antikörper) complex may be involved in this process.

  3. BAG3 directly stabilizes hexokinase 2 (zeige HK2 Antikörper) mRNA and promotes aerobic glycolysis in pancreatic cancer cells.

  4. BAG3 expression is required for neuronal differentiation and migration.

  5. interaction between BAG3 and HSP70 (zeige HSP70 Antikörper) is essential for BAG3 to stabilize small heat shock proteins and maintain cardiomyocyte protein homeostasis

  6. The spatial regulation of mTORC1 exerted by BAG3 apparently provides the basis for a simultaneous induction of autophagy and protein synthesis to maintain the proteome under mechanical strain.

  7. Genetic variation in BAG3 plays an important role in the prevention of ischemic tissue necrosis.

  8. The aim of this study was to investigate the possible hemodynamic effects of BAG3 performing both in vitro and in vivo experiments.

  9. Our findings that BAG3 is localized at the sarcolemma and t-tubules while modulating myocyte contraction and action potential duration through specific interaction with the beta1-adrenergic receptor and L-type Ca(2 (zeige CA2 Antikörper)+) channel provide novel insight into the role of BAG3 in cardiomyopathies and increased arrhythmia risks in heart failure.

  10. molecular association of MyHC (zeige MYH13 Antikörper) and BIS is necessary for MyHC (zeige MYH13 Antikörper) stabilization in skeletal muscle.

BAG3 Antigen-Profil

Protein Überblick

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Genbezeichner und Symbole assoziert mit BAG3

  • BCL2 associated athanogene 3 L homeolog (bag3.L) Antikörper
  • BCL2-associated athanogene 3 (bag3) Antikörper
  • BCL2 associated athanogene 3 (BAG3) Antikörper
  • BCL2 associated athanogene 3 (bag3) Antikörper
  • BCL-2-associated athanogene 3 (BAG3) Antikörper
  • BCL2-associated athanogene 3 (Bag3) Antikörper
  • Bcl2-associated athanogene 3 (Bag3) Antikörper
  • AA407278 Antikörper
  • ATBAG3 Antikörper
  • BAG-3 Antikörper
  • BAG3 Antikörper
  • bag3-A Antikörper
  • BCL-2-associated athanogene 3 Antikörper
  • Bis Antikörper
  • CAIR-1 Antikörper
  • MFM6 Antikörper
  • mg638 Antikörper
  • MGC53113 Antikörper
  • T28J14.160 Antikörper
  • T28J14_160 Antikörper
  • zgc:100859 Antikörper

Bezeichner auf Proteinebene für BAG3

BCL2-associated athanogene 3 , BAG family molecular chaperone regulator 3 , BAG family molecular chaperone regulator 3-like , BCL2-binding athanogene 3 , bcl-2-binding protein Bis , docking protein CAIR-1 , BAG-3 , Bcl-2-binding protein Bis , Bcl-2-interacting death suppressor , bcl-2-associated athanogene 3

GENE ID SPEZIES
379174 Xenopus laevis
445139 Danio rerio
450778 Pan troglodytes
714420 Macaca mulatta
100145358 Xenopus (Silurana) tropicalis
100228262 Taeniopygia guttata
100481230 Ailuropoda melanoleuca
830613 Arabidopsis thaliana
9531 Homo sapiens
29810 Mus musculus
293524 Rattus norvegicus
486916 Canis lupus familiaris
782633 Bos taurus
423931 Gallus gallus
100156989 Sus scrofa
100358030 Oryctolagus cuniculus
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