anti-Arylsulfatase A (ARSA) Antikörper

The protein encoded by ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus ARSA ARSA 11883 P50428
Anti-Human ARSA ARSA 410 P15289
Anti-Ratte ARSA ARSA 315222  
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Top anti-Arylsulfatase A Antikörper auf antikoerper-online.de

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ARSA Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ARSA Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>COLO205 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Maus Ziege Unkonjugiert ELISA, WB ABIN238536 (0.5µg/ml) staining of Mouse Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-ARSA Picoband antibody, Western blotting All lanes: Anti ARSA  at 0.5ug/ml Lane 1: Rat Testis Tissue Lysate at 50ug Lane 2: Rat Pancreas Tissue Lysate at 50ug Lane 3: Rat Skeletal Muscle Tissue Lysate at 50ug Lane 4: Mouse Kidney Tissue Lysate at 50ug Lane 5: MCF-7 Whole Cell Lysate at 40ug Predicted bind size: 54KD Observed bind size: 54KD Anti-ARSA Picoband antibody,IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Arylsulfatase A staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Arylsulfatase A expression in HEK293T (A), mouse kidney (B), rat kidney (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from Jurkat/COLO cells, using ARSA Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using ARSA Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: H1299 B: Hela 10% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Maus Kaninchen Unkonjugiert IP, ELISA, WB 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$218.90
Details
Human Kaninchen Unkonjugiert WB ARSA Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ARSA antibody detected the ARSA protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details

Am meisten referenzierte anti-Arylsulfatase A Antikörper

  1. Mouse (Murine) Polyclonal Arylsulfatase A Primary Antibody für ELISA, WB - ABIN238536 : Sevin, Benraiss, Van Dam, Bonnin, Nagels, Verot, Laurendeau, Vidaud, Gieselmann, Vanier, De Deyn, Aubourg, Cartier: Intracerebral adeno-associated virus-mediated gene transfer in rapidly progressive forms of metachromatic leukodystrophy. in Human molecular genetics 2005 (PubMed)
    Show all 5 Pubmed References

Weitere Antikörper gegen Arylsulfatase A Interaktionspartner

Mouse (Murine) Arylsulfatase A (ARSA) Interaktionspartner

  1. Multipotential Neural precursors deficient in arylsulfatase A show a higher ratio of long versus short fatty acid sulfatides, reduction in PDGFRa (zeige PDGFRA Antikörper), decreased AKT (zeige AKT1 Antikörper) phosphorylation, and increased exosomal shedding of PDGFRa (zeige PDGFRA Antikörper).

  2. Sperm arylsulfatase A binds to mZP2 and mZP3 glycoproteins in a nonenzymatic manner.

  3. Sulfogalactosylglycerolipid was a physiological substrate of Sertoli lysosomal arylsulfatase A

  4. study provides the first proof of cognitive deficit and impaired synaptic plasticity in an MLD (zeige MBP Antikörper) mouse model.

  5. ArsA plays a role as a novel component of the extracellular matrix which could be very useful for clarifying the mechanisms underlying some of the syndromes caused by functional deficiency of the Ars (zeige SLURP1 Antikörper) genes.

  6. Data demonstrate a delay in myelin formation in ASA-deficient mice at 2 weeks of age, as a consequence of inability to degrade sulfatide.

  7. Since high cholesterol levels are important for myelination, and various cellular processes, like vesicular trafficking and signal transduction, reduced cholesterol levels might be an important factor in the molecular pathology of MLD (zeige MBP Antikörper).

  8. ASA-deficient [ASA(-/-)] mice overexpressing the sulfatide synthesizing enzymes causes hyperexcitability and axonal degeneration in a mouse model of metachromatic leukodystrophy

  9. The increasing sulfatide storage in ASA(-/-) mice leads to neurological symptoms and morphological alterations that are reminiscent of human MLD (zeige MBP Antikörper).

  10. Safety of Arsa overexpression for gene therapy of metachromatic leukodystrophy was evaluated.

Human Arylsulfatase A (ARSA) Interaktionspartner

  1. The novel p.L113P mutation in a Pakistani family with late infantile MLD has a pathogenic and destructive effect on the protein structure and function of ARSA.

  2. siblings exhibited compound heterozygous variants {[c.302G>T]+[c.1344dupC]} in the ARSA gene, and both of the variants have been reported as disease-causing mutations previouslyfa

  3. First report of arylsulfatase A pseudodeficiency (ASA-PD) allele and haplotype frequencies in a North African population, reveals relatively high prevalence of the ASA-PD allele in the Tunisian population with an intermediate genetic structure between Africans, Middle-eastern and Europeans most probably linked to the particular geographic location of Tunisia and the several population incursions throughout its history

  4. an extensive review of all the ARSA-causative variants published in the literature to date, accounting for a total of 200 ARSA allele types (review)

  5. Data indicate a significant correlation between the mutation of c.622delC(p.His208Metfs*46) in the arylsulfatase A (ARSA) gene and the phenotype OF metachromatic leukodystrophy.

  6. Sixteen novel mutations that cause metachromatic leukodystrophy have been identified in the arylsulfatase A gene.

  7. Studied brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor (zeige INSR Antikörper).

  8. HSPA2 (zeige HSPA2 Antikörper) regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition, such as arylsulfatase A and SPAM1 (zeige SPAM1 Antikörper).

  9. The interaction between SPAM1 (zeige SPAM1 Antikörper), ARSA and HSPA2 (zeige HSPA2 Antikörper) in a multimeric complex mediating sperm-egg interaction.

  10. This is the first report that human adipocytes express functional DAR (zeige ATP2A2 Antikörper) and ARSA, suggesting a regulatory role for peripheral DA in adipose functions.

Pig (Porcine) Arylsulfatase A (ARSA) Interaktionspartner

Arylsulfatase A (ARSA) Antigen-Profil

Protein Überblick

The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Genbezeichner und Symbole assoziert mit anti-Arylsulfatase A (ARSA) Antikörper

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Bezeichner auf Proteinebene für anti-Arylsulfatase A (ARSA) Antikörper

arylsulfatase A , Arylsulfatase A , cerebroside-sulfatase , ASA

GENE ID SPEZIES
458946 Pan troglodytes
541416 Danio rerio
716500 Macaca mulatta
1791590 Rhodopirellula baltica SH 1
1791953 Rhodopirellula baltica SH 1
1795188 Rhodopirellula baltica SH 1
1796341 Rhodopirellula baltica SH 1
1796692 Rhodopirellula baltica SH 1
1797062 Rhodopirellula baltica SH 1
100012344 Monodelphis domestica
100195737 Salmo salar
11883 Mus musculus
410 Homo sapiens
315222 Rattus norvegicus
474457 Canis lupus familiaris
396973 Sus scrofa
505514 Bos taurus
426863 Gallus gallus
100351118 Oryctolagus cuniculus
447252 Xenopus laevis
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