Ankyrin Repeat Domain 27 (VPS9 Domain) Proteine (ANKRD27)

May be a Rab21 guanine exchange factor and regulate endosome dynamics.. Zusätzlich bieten wir Ihnen ANKRD27 Antikörper (25) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ANKRD27 84079 Q96NW4
ANKRD27 245886 Q3UMR0
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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ANKRD27 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27) Interaktionspartnern

Human Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27) Interaktionspartner

  1. VARP regulates endosomal trafficking and and retromer-mediated endosome-to-plasma membrane sorting of transmembrane proteins by binding to rab GTP-Binding Proteins and R-SNARE VAMP7 [review].

  2. Eosinophilic esophagitis was associate with increased expression of ANKRD27.

  3. VAMP7-SNARE motif is trapped between Varp and the VAMP7 longin domain, and hence Varp kinetically inhibits the ability of VAMP7 to form SNARE complexes

  4. Varp physically interacts with Rab38, and preferentially binds to the active GTP-bound form of Rab38 both in vitro and in vivo.

  5. show that TI-VAMP interacts with the Vps9 domain and ankyrin-repeat-containing protein Varp, a guanine nucleotide exchange factor of the small GTPase Rab21, through a specific domain herein called the interacting domain.

Mouse (Murine) Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27) Interaktionspartner

  1. RACK1 competes with Rab40C for binding to the ANKR2 domain of Varp and regulates dendrite outgrowth through stabilization of Varp in mouse melanocytes

  2. both the Rab32/38 binding activity and VAMP7 binding activity of Varp are essential for trafficking of Tyrp1 in melanocytes but activation of Rab21 by the VPS9 domain is not necessary for Tyrp1 trafficking

  3. Varp is a potential Rab21 guanine nucleotide exchange factor and might regulate endosome dynamics in vivo

  4. Varp functions as the Rab32/38 effector that controls trafficking of Tyrp1 in melanocytes.

ANKRD27 Protein Überblick

Protein Überblick

May be a Rab21 guanine exchange factor and regulate endosome dynamics.

Genbezeichner und Symbole assoziert mit ANKRD27

  • ankyrin repeat domain 27 (ANKRD27)
  • ankyrin repeat domain 27 (VPS9 domain) (Ankrd27)
  • AA408090 Protein
  • BC016493 Protein
  • D330003H11Rik Protein
  • Varp Protein

Bezeichner auf Proteinebene für ANKRD27

VPS9 domain-containing protein , VPS9-ankyrin-repeat protein , Vps9 domain and ankyrin-repeat-containing protein , ankyrin repeat domain-containing protein 27 , VPS9-ankyrin repeat-containing protein , mFLJ00040 protein

GENE ID SPEZIES
84079 Homo sapiens
245886 Mus musculus
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